公开(公告)号：US20210292823A1

公开(公告)日：2021-09-23

申请号：US16894664

申请日：2020-06-05

申请人： Feng Zhang ,  Jonathan Gootenberg ,  Omar Abudayyeh ,  Julia Joung ,  Alim Ladha ,  Han Altae-Tran ,  Guilhem Faure

发明人： Feng Zhang ,  Jonathan Gootenberg ,  Omar Abudayyeh ,  Julia Joung ,  Alim Ladha ,  Han Altae-Tran ,  Guilhem Faure

IPC分类号： C12Q1/6844 ,  B01L7/00 ,  B01L3/00

摘要： Systems and methods for rapid diagnostics related to the use of isothermal amplification reagents for detection of microbial species, including coronavirus, and methods of use, are provided.

公开(公告)号：US20210292824A1

公开(公告)日：2021-09-23

申请号：US16894670

申请日：2020-06-05

申请人： Feng Zhang ,  Jonathan Gootenberg ,  Omar Abudayyeh ,  Julia Joung ,  Alim Ladha ,  Han Altae-Tran ,  Guilhem Faure

发明人： Feng Zhang ,  Jonathan Gootenberg ,  Omar Abudayyeh ,  Julia Joung ,  Alim Ladha ,  Han Altae-Tran ,  Guilhem Faure

IPC分类号： C12Q1/6844 ,  C12N9/22 ,  C12Q1/6806

摘要： Systems and methods for rapid diagnostics related to the use of CRISPR effector systems and optimized guide sequences for detection of coronavirus, including multiplex lateral flow diagnostic devices and methods of use, are provided.

公开(公告)号：US20210292721A1

公开(公告)日：2021-09-23

申请号：US16894678

申请日：2020-06-05

申请人： Feng Zhang ,  Jonathan Gootenberg ,  Omar Abudayyeh ,  Julia Joung ,  Alim Ladha ,  Han Altae-Tran ,  Guilhem Faure

发明人： Feng Zhang ,  Jonathan Gootenberg ,  Omar Abudayyeh ,  Julia Joung ,  Alim Ladha ,  Han Altae-Tran ,  Guilhem Faure

IPC分类号： C12N9/22 ,  C12N9/12 ,  C12N9/78

摘要： Engineered or non-naturally occurring systems and compositions comprising a novel Cas12b and a guide molecule. Also provided include methods of use the systems and compositions, including in treating and diagnosing diseases.