公开(公告)号：US20210106521A1

公开(公告)日：2021-04-15

申请号：US16599629

申请日：2019-10-11

Applicant: Fertin Pharma A/S

Inventor： Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen ,  Kent Albin Nielsen ,  Rikke Pranger-Rasmussen

IPC: A61K9/00 ,  A61K31/465 ,  A61K47/26 ,  A61K47/32

Abstract: A water-dissolvable compressed oral nicotine lozenge is disclosed, the oral nicotine lozenge comprising a first module and a second module, the first and the second modules being fused by compression, the first module being a lozenge module comprising at least one sugar alcohol and the second module being an FDT-module comprising at least one sugar alcohol and nicotine. Also, a method of manufacturing a water-dissolvable compressed oral nicotine lozenge is disclosed.

公开(公告)号：US20240000706A1

公开(公告)日：2024-01-04

申请号：US18364862

申请日：2023-08-03

Applicant: Fertin Pharma A/S

Inventor： Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen ,  Kent Albin Nielsen ,  Rikke Pranger-Rasmussen

IPC: A61K9/00 ,  A61K31/465 ,  A61K47/26 ,  A61K47/32

CPC classification number: A61K9/0056 ,  A61K47/32 ,  A61K47/26 ,  A61K31/465

Abstract: A water-dissolvable compressed oral nicotine lozenge is disclosed, the oral nicotine lozenge comprising a first module and a second module, the first and the second modules being fused by compression, the first module being a lozenge module comprising at least one sugar alcohol and the second module being an FDT-module comprising at least one sugar alcohol and nicotine. Also, a method of manufacturing a water-dissolvable compressed oral nicotine lozenge is disclosed.

公开(公告)号：US20230181478A1

公开(公告)日：2023-06-15

申请号：US17644182

申请日：2021-12-14

Applicant: Fertin Pharma A/S

Inventor： Kent Albin Nielsen ,  Rikke Pranger-Rasmussen ,  Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen

IPC: A61K9/20 ,  A61K31/4439

CPC classification number: A61K9/2086 ,  A61K31/4439 ,  A61K9/2018 ,  A61K9/2009 ,  A61K9/2013

Abstract: A water-dissolvable nicotine tablet is disclosed, the nicotine tablet comprising at least a first compressed module and a second compressed module, wherein the first compressed module is an FDT-module and comprises nicotine, alkaline pH regulating agent, and disintegrant, and, wherein the second compressed module is a lozenge-module and comprises acidic pH regulating agent. Also, a method of manufacturing a nicotine tablet is disclosed.

公开(公告)号：US12194149B2

公开(公告)日：2025-01-14

申请号：US18464911

申请日：2023-09-11

Applicant: Fertin Pharma A/S

Inventor： Kent Albin Nielsen ,  Rikke Pranger-Rasmussen ,  Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen

IPC: A61K9/20 ,  A61K31/4439

Abstract: A water-dissolvable nicotine tablet is disclosed, the nicotine tablet comprising at least a first compressed module and a second compressed module, wherein the first compressed module is an FDT-module and comprises nicotine, alkaline pH regulating agent, and disintegrant, and, wherein the second compressed module is a lozenge-module and comprises acidic pH regulating agent. Also, a method of manufacturing a nicotine tablet is disclosed.

公开(公告)号：US11759419B2

公开(公告)日：2023-09-19

申请号：US16599629

申请日：2019-10-11

Applicant: Fertin Pharma A/S

Inventor： Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen ,  Kent Albin Nielsen ,  Rikke Pranger-Rasmussen

IPC: A61K9/00 ,  A61K31/465 ,  A61K47/26 ,  A61K47/32

CPC classification number: A61K9/0056 ,  A61K31/465 ,  A61K47/26 ,  A61K47/32

Abstract: A water-dissolvable compressed oral nicotine lozenge is disclosed, the oral nicotine lozenge comprising a first module and a second module, the first and the second modules being fused by compression, the first module being a lozenge module comprising at least one sugar alcohol and the second module being an FDT-module comprising at least one sugar alcohol and nicotine. Also, a method of manufacturing a water-dissolvable compressed oral nicotine lozenge is disclosed.

公开(公告)号：US20250082569A1

公开(公告)日：2025-03-13

申请号：US18883730

申请日：2024-09-12

Applicant: Fertin Pharma A/S

Inventor： Rune Faurby Carlsson ,  Kent Albin Nielsen ,  Rikke Pranger-Rasmussen ,  Bruno Provstgaard Nielsen ,  Helle Martinussen

IPC: A61K9/00 ,  A24B15/16 ,  A61K9/20 ,  A61K9/24 ,  A61K31/465

Abstract: An orally disintegrating nicotine tablet for fast nicotine craving relief is disclosed, the tablet comprising nicotine, disintegrant, and at least one sugar alcohol, wherein the tablet comprises less than 0.4% by weight of flavor. A further orally disintegrating nicotine tablet and an oral nicotine tablet is disclosed.

公开(公告)号：US20240000713A1

公开(公告)日：2024-01-04

申请号：US18464911

申请日：2023-09-11

Applicant: Fertin Pharma A/S

Inventor： Kent Albin Nielsen ,  Rikke Pranger-Rasmussen ,  Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen

IPC: A61K9/20 ,  A61K31/4439

CPC classification number: A61K9/2086 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2018 ,  A61K31/4439

Abstract: A water-dissolvable nicotine tablet is disclosed, the nicotine tablet comprising at least a first compressed module and a second compressed module, wherein the first compressed module is an FDT-module and comprises nicotine, alkaline pH regulating agent, and disintegrant, and, wherein the second compressed module is a lozenge-module and comprises acidic pH regulating agent. Also, a method of manufacturing a nicotine tablet is disclosed.

公开(公告)号：US11786473B2

公开(公告)日：2023-10-17

申请号：US17644182

申请日：2021-12-14

Applicant: Fertin Pharma A/S

Inventor： Kent Albin Nielsen ,  Rikke Pranger-Rasmussen ,  Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen

IPC: A61K9/20 ,  A61K31/4439

CPC classification number: A61K9/2086 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2018 ,  A61K31/4439

Abstract: A water-dissolvable nicotine tablet is disclosed, the nicotine tablet comprising at least a first compressed module and a second compressed module, wherein the first compressed module is an FDT-module and comprises nicotine, alkaline pH regulating agent, and disintegrant, and, wherein the second compressed module is a lozenge-module and comprises acidic pH regulating agent. Also, a method of manufacturing a nicotine tablet is disclosed.