公开(公告)号：US20240000706A1

公开(公告)日：2024-01-04

申请号：US18364862

申请日：2023-08-03

Applicant: Fertin Pharma A/S

Inventor： Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen ,  Kent Albin Nielsen ,  Rikke Pranger-Rasmussen

IPC: A61K9/00 ,  A61K31/465 ,  A61K47/26 ,  A61K47/32

CPC classification number: A61K9/0056 ,  A61K47/32 ,  A61K47/26 ,  A61K31/465

Abstract: A water-dissolvable compressed oral nicotine lozenge is disclosed, the oral nicotine lozenge comprising a first module and a second module, the first and the second modules being fused by compression, the first module being a lozenge module comprising at least one sugar alcohol and the second module being an FDT-module comprising at least one sugar alcohol and nicotine. Also, a method of manufacturing a water-dissolvable compressed oral nicotine lozenge is disclosed.

公开(公告)号：US20230181478A1

公开(公告)日：2023-06-15

申请号：US17644182

申请日：2021-12-14

Applicant: Fertin Pharma A/S

Inventor： Kent Albin Nielsen ,  Rikke Pranger-Rasmussen ,  Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen

IPC: A61K9/20 ,  A61K31/4439

CPC classification number: A61K9/2086 ,  A61K31/4439 ,  A61K9/2018 ,  A61K9/2009 ,  A61K9/2013

Abstract: A water-dissolvable nicotine tablet is disclosed, the nicotine tablet comprising at least a first compressed module and a second compressed module, wherein the first compressed module is an FDT-module and comprises nicotine, alkaline pH regulating agent, and disintegrant, and, wherein the second compressed module is a lozenge-module and comprises acidic pH regulating agent. Also, a method of manufacturing a nicotine tablet is disclosed.

公开(公告)号：US11351103B2

公开(公告)日：2022-06-07

申请号：US15783151

申请日：2017-10-13

Applicant: Johnson & Johnson Consumer Inc. ,  Fertin Pharma A/S

Inventor： Anthony R. Geonnotti ,  Patricia L. Golas ,  Helle Wittorff ,  Heidi Ziegler Bruun ,  Dorthe Shackinger Boesen

IPC: A61K8/60 ,  A61Q11/00 ,  A61K9/20 ,  A61K8/02 ,  A61K9/00

Abstract: Provided are methods of providing at least one oral care benefit by introducing a tablet into the oral cavity to generate a fluid and forcing at least a portion of fluid generated around the oral cavity, for example, by swishing, rinsing, washing, etc., to provide an oral care benefit.

公开(公告)号：US20210106521A1

公开(公告)日：2021-04-15

申请号：US16599629

申请日：2019-10-11

Applicant: Fertin Pharma A/S

Inventor： Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen ,  Kent Albin Nielsen ,  Rikke Pranger-Rasmussen

IPC: A61K9/00 ,  A61K31/465 ,  A61K47/26 ,  A61K47/32

Abstract: A water-dissolvable compressed oral nicotine lozenge is disclosed, the oral nicotine lozenge comprising a first module and a second module, the first and the second modules being fused by compression, the first module being a lozenge module comprising at least one sugar alcohol and the second module being an FDT-module comprising at least one sugar alcohol and nicotine. Also, a method of manufacturing a water-dissolvable compressed oral nicotine lozenge is disclosed.

公开(公告)号：US20180140521A1

公开(公告)日：2018-05-24

申请号：US15783151

申请日：2017-10-13

Applicant: Johnson & Johnson Consumer Inc. ,  Fertin Pharma A/S

Inventor： Anthony R. Geonnotti ,  Patricia L. Golas ,  Helle Wittorff ,  Heidi Ziegler Bruun ,  Dorthe Shackinger Boesen

IPC: A61K8/34 ,  A61Q11/00 ,  A61K8/02 ,  A61K8/92

CPC classification number: A61K8/345 ,  A61K8/02 ,  A61K8/0216 ,  A61K8/022 ,  A61K8/60 ,  A61K8/922 ,  A61K2800/92 ,  A61Q11/00

Abstract: Provided are methods of providing at least one oral care benefit by introducing a tablet into the oral cavity to generate a fluid and forcing at least a portion of fluid generated around the oral cavity, for example, by swishing, rinsing, washing, etc., to provide an oral care benefit.

公开(公告)号：US20240000713A1

公开(公告)日：2024-01-04

申请号：US18464911

申请日：2023-09-11

Applicant: Fertin Pharma A/S

Inventor： Kent Albin Nielsen ,  Rikke Pranger-Rasmussen ,  Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen

IPC: A61K9/20 ,  A61K31/4439

CPC classification number: A61K9/2086 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2018 ,  A61K31/4439

Abstract: A water-dissolvable nicotine tablet is disclosed, the nicotine tablet comprising at least a first compressed module and a second compressed module, wherein the first compressed module is an FDT-module and comprises nicotine, alkaline pH regulating agent, and disintegrant, and, wherein the second compressed module is a lozenge-module and comprises acidic pH regulating agent. Also, a method of manufacturing a nicotine tablet is disclosed.

公开(公告)号：US11786473B2

公开(公告)日：2023-10-17

申请号：US17644182

申请日：2021-12-14

Applicant: Fertin Pharma A/S

Inventor： Kent Albin Nielsen ,  Rikke Pranger-Rasmussen ,  Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen

IPC: A61K9/20 ,  A61K31/4439

CPC classification number: A61K9/2086 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2018 ,  A61K31/4439

Abstract: A water-dissolvable nicotine tablet is disclosed, the nicotine tablet comprising at least a first compressed module and a second compressed module, wherein the first compressed module is an FDT-module and comprises nicotine, alkaline pH regulating agent, and disintegrant, and, wherein the second compressed module is a lozenge-module and comprises acidic pH regulating agent. Also, a method of manufacturing a nicotine tablet is disclosed.

公开(公告)号：US11406630B2

公开(公告)日：2022-08-09

申请号：US16065986

申请日：2018-06-25

Applicant: Fertin Pharma A/S

Inventor： Heidi Ziegler Bruun

IPC: A61K31/465 ,  A61K47/22 ,  A61K47/38 ,  A61K9/00 ,  A47L9/28 ,  A24B15/16 ,  A61K47/12 ,  A61K47/32

Abstract: A pouch designed for administration of an active ingredient in the oral cavity is disclosed, the pouch containing a matrix composition including a combination of nicotine and a water-soluble composition.

公开(公告)号：US11096412B2

公开(公告)日：2021-08-24

申请号：US16894114

申请日：2020-06-05

Applicant: Fertin Pharma A/S

Inventor： My Ly Lao Stahl ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen ,  Bine Hare Jakobsen

IPC: A24B15/16 ,  A24B13/00 ,  A24B15/30 ,  A24B15/40 ,  A24B15/32 ,  A24B15/42

Abstract: A nicotine pouch composition is disclosed, the pouch composition comprising free-base nicotine and having a water content of at least 15% by weight of said pouch composition. Furthermore, an oral nicotine pouch product comprising the pouch composition and a method for manufacturing the oral nicotine pouch product is disclosed.

公开(公告)号：US12194149B2

公开(公告)日：2025-01-14

申请号：US18464911

申请日：2023-09-11

Applicant: Fertin Pharma A/S

Inventor： Kent Albin Nielsen ,  Rikke Pranger-Rasmussen ,  Dorthe Schackinger Boesen ,  Heidi Ziegler Bruun ,  Bruno Provstgaard Nielsen

IPC: A61K9/20 ,  A61K31/4439

Abstract: A water-dissolvable nicotine tablet is disclosed, the nicotine tablet comprising at least a first compressed module and a second compressed module, wherein the first compressed module is an FDT-module and comprises nicotine, alkaline pH regulating agent, and disintegrant, and, wherein the second compressed module is a lozenge-module and comprises acidic pH regulating agent. Also, a method of manufacturing a nicotine tablet is disclosed.