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公开(公告)号:US20050244973A1
公开(公告)日:2005-11-03
申请号:US10845773
申请日:2004-05-14
申请人: Frank Andel , Hans Bitter , Mikhail Belov , Michael Brown , Alfred Greenquist , Jonathan Heller , Alexander Sassi , John Stults , Kathy Stults
发明人: Frank Andel , Hans Bitter , Mikhail Belov , Michael Brown , Alfred Greenquist , Jonathan Heller , Alexander Sassi , John Stults , Kathy Stults
IPC分类号: G01N33/48 , G01N33/574
CPC分类号: G01N33/57434 , Y10T436/24
摘要: The present invention provides methods for diagnosing cancers, such as prostate cancer. Also, methods for evaluating the prostate cancer state of a patient are described herein. These methods involve the detection, analysis, and classification of biological patterns in biological samples. The biological patterns are obtained using, for example, mass spectrometry systems, antibody based techniques, or nucleic acid based techniques. The present invention also includes therapeutic and prophylactic agents that target the biomarkers described herein. Also, the present invention provides methods for the treatment of prostate cancer using the markers described herein or agents that mimic the properties of these markers.
摘要翻译: 本发明提供了诊断癌症的方法,例如前列腺癌。 此外,本文描述了用于评估患者的前列腺癌状态的方法。 这些方法涉及生物样品中生物样本的检测,分析和分类。 使用例如质谱系统,基于抗体的技术或基于核酸的技术获得生物学模式。 本发明还包括靶向本文所述的生物标志物的治疗和预防剂。 此外,本发明提供了使用本文所述的标记物治疗前列腺癌的方法或模拟这些标记的性质的试剂。
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公开(公告)号:US20070009970A1
公开(公告)日:2007-01-11
申请号:US11178245
申请日:2005-07-08
申请人: Jonathan Heller , Michael Brown , David de Valpine , Hans Bitter , Kathy Stults , Isabelle Guyon , Robert Tibshirani
发明人: Jonathan Heller , Michael Brown , David de Valpine , Hans Bitter , Kathy Stults , Isabelle Guyon , Robert Tibshirani
IPC分类号: G01N33/574 , G06F19/00
CPC分类号: G01N33/57434 , G01N33/6848
摘要: The present invention provides methods for diagnosing cancers, such as prostate cancer. Also, methods for evaluating the prostate cancer state of a patient are described herein. These methods involve the detection, analysis, and classification of biological patterns in biological samples. The biological patterns are obtained using, for example, mass spectrometry systems, antibody based techniques, or nucleic acid based techniques. The present invention also includes therapeutic and prophylactic agents that target the biomarkers described herein. Also, the present invention provides methods for the treatment of prostate cancer using the markers described herein or agents that mimic the properties of these markers.
摘要翻译: 本发明提供了诊断癌症的方法,例如前列腺癌。 此外,本文描述了用于评估患者的前列腺癌状态的方法。 这些方法涉及生物样品中生物样本的检测,分析和分类。 使用例如质谱系统,基于抗体的技术或基于核酸的技术获得生物学模式。 本发明还包括靶向本文所述的生物标志物的治疗和预防剂。 此外,本发明提供了使用本文所述的标记物治疗前列腺癌的方法或模拟这些标记的性质的试剂。
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