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123 条记录 (耗时 0.037 秒)

    NOVEL COMPOUNDS
    6.
    发明申请
    NOVEL COMPOUNDS 审中-公开
    新型化合物

    公开(公告)号：US20100256105A1

    公开(公告)日：2010-10-07

    申请号：US12749919

    申请日：2010-03-30

    申请人： Frank Burkamp ,  Peter Hansen

    发明人： Frank Burkamp ,  Peter Hansen

    IPC分类号： A61K31/58 ,  C07J71/00 ,  A61P11/06 ,  A61P11/02

    CPC分类号： A61K31/58 ,  C07J71/0047

    摘要： The present invention provides compounds of formula (I) wherein n, p, R1, R2, X1, X2, X3, X4, X5, R3a, R3b, R4, R5 and R6 are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them and their use in therapy.

    摘要翻译： 本发明提供式（I）化合物，其中n，p，R1，R2，X1，X2，X3，X4，X5，R3a，R3b，R4，R5和R6如说明书中所定义， ，含有它们的药物组合物及其在治疗中的用途。

    NOVEL COMBINATIONS
    7.
    发明申请
    NOVEL COMBINATIONS 审中-公开
    新的组合

    公开(公告)号：US20100261690A1

    公开(公告)日：2010-10-14

    申请号：US12749888

    申请日：2010-03-30

    申请人： Frank Burkamp ,  Peter Hansen

    发明人： Frank Burkamp ,  Peter Hansen

    IPC分类号： A61K31/58 ,  A61P11/00

    CPC分类号： A61K45/06 ,  A61K9/0075 ,  A61K31/58 ,  A61K2300/00

    摘要： The invention provides a pharmaceutical product comprising, in combination, (1) a named glucocorticosteroid receptor agonist and (2) a β2 adrenoreceptor agonist, a dual β2 adrenoreceptor agonist/M3 receptor antagonist, a muscarinic antagonist, a p38 kinase inhibitor, a neutrophil elastase inhibitor, a phosphodiesterase PDE4 inhibitor, an IKK2 kinase inhibitor or a non-steroidal glucocorticoid receptor agonist, and the use of said product in treating respiratory diseases.

    摘要翻译： 本发明提供一种药物产品，其组合包含（1）命名的糖皮质激素受体激动剂和（2）肾上腺素受体激动剂，双重肾上腺素受体激动剂/ M3受体拮抗剂，毒蕈碱拮抗剂，p38激酶抑制剂 ，嗜中性粒细胞弹性蛋白酶抑制剂，磷酸二酯酶PDE4抑制剂，IKK2激酶抑制剂或非甾体糖皮质激素受体激动剂，以及所述产品在治疗呼吸系统疾病中的用途。

    Single and multiple cell battery with built-in controller
    8.
    发明授权
    Single and multiple cell battery with built-in controller 有权
    单电池和多节电池，内置控制器

    公开(公告)号：US09397370B2

    公开(公告)日：2016-07-19

    申请号：US11726101

    申请日：2007-03-21

    申请人： Dragan Danilo Nebrigic ,  Milan Marcel Jevtitch ,  Vladimir Gartstein ,  William Thomas Mllam ,  James Vig Sherrill ,  Nicholas Busko ,  Peter Hansen

    发明人： Dragan Danilo Nebrigic ,  Milan Marcel Jevtitch ,  Vladimir Gartstein ,  William Thomas Mllam ,  James Vig Sherrill ,  Nicholas Busko ,  Peter Hansen

    IPC分类号： H01M6/00 ,  H01M10/42 ,  H01M10/44

    CPC分类号： H01M10/42 ,  H01M10/44

    摘要： Single and multiple cell batteries are provided with built-in controllers that monitor the cell or cells and provide a safety disconnect when certain monitored conditions are detected by the controller. Preferred single and multiple cell batteries have their cell or cells within a container having a positive terminal and a negative terminal. The built-in controller monitors the cell or cells for each of the following conditions: over temperature, short-circuit, overcharge, and over-discharge and the controller provides a safety disconnect when one of the monitored conditions exist. A multiple cell battery includes a built-in controller that monitors the temperature of the cells and provides a safety disconnect that electronically disconnects all of the cells when at least one of the cells exceeds a predetermined temperature, or a controller that monitors the state of charge of each of the cells and individually controls the charge cycle of each of the cells, or a controller that monitors the temperature of the cells and to provides a safety disconnect when at least one of the cells exceeds a predetermined temperature.

    摘要翻译： 提供单电池和多电池电池，内置控制器，用于监控电池或电池，并在控制器检测到某些监控条件时提供安全断开。 优选的单电池和多电池电池将其电池或电池放在具有正极端子和负极端子的容器内。 内置控制器可监控以下每种情况下的电池或电池：过温，短路，过充电和过放电，并且当存在受监控条件之一时，控制器提供安全断开。 多单元电池包括内置的控制器，其监视电池的温度，并提供安全断开器，当电池中的至少一个电池超过预定温度时电子断开所有电池，或监视充电状态的控制器 并且单独地控制每个电池的充电循环，或者当至少一个电池超过预定温度时监视电池的温度并提供安全断开的控制器。

    Integrated Digital Discriminator For a Silicon Photomultiplier
    10.
    发明申请
    Integrated Digital Discriminator For a Silicon Photomultiplier 有权
    硅光电倍增管的集成数字鉴相器

    公开(公告)号：US20140029715A1

    公开(公告)日：2014-01-30

    申请号：US13556331

    申请日：2012-07-24

    申请人： Peter Hansen ,  Michael E. Casey ,  Stefan B. Siegel

    发明人： Peter Hansen ,  Michael E. Casey ,  Stefan B. Siegel

    IPC分类号： G06M15/00 ,  H01J40/00

    CPC分类号： G01J1/44 ,  G01T1/248 ,  G01T1/2985 ,  H03K3/037 ,  H03K5/135 ,  H03K2005/00078

    摘要： Apparatuses and methods are provided that minimize the effects of dark-current pulses. For example, in one embodiment of the invention, a method is provided where a first pixel is struck (i.e., a primary pixel). Pixels struck within a fixed time frame after the primary pixel is struck are referred to as secondary pixels. After a short fixed time frame has expired, the number of primary and secondary pixels is added. If the count exceeds a threshold, the primary pixel was activated by the first (or early) photon from a true gamma event. If the threshold is not met then it is likely the primary pixel generated a dark pulse that should be ignored.

    摘要翻译： 提供了使暗电流脉冲的影响最小化的装置和方法。 例如，在本发明的一个实施例中，提供了一种方法，其中第一像素被撞击（即，主像素）。 在主要像素被击打之后的固定时间帧内撞击的像素被称为次要像素。 在短的固定时间段到期后，添加主要和次要像素的数量。 如果计数超过阈值，则主像素由来自真实伽马事件的第一（或早）光子激活。 如果阈值不满足，则主要像素可能产生应忽略的暗脉冲。