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1.Cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors 有权
标题翻译: 环状尿素衍生物,其制备方法及其作为激酶抑制剂的药物用途公开(公告)号:US07935819B2
公开(公告)日:2011-05-03
申请号:US12173380
申请日:2008-07-15
申请人: Frank Halley , Youssef El-Ahmad , Victor Certal , Corinne Venot , Anne Dagallier , Hartmut Strobel , Kurt Ritter , Sven Ruf
发明人: Frank Halley , Youssef El-Ahmad , Victor Certal , Corinne Venot , Anne Dagallier , Hartmut Strobel , Kurt Ritter , Sven Ruf
IPC分类号: C07D239/02
CPC分类号: C07D401/14 , C07D401/06 , C07D403/06 , C07D403/14
摘要: Compounds of formula (I): wherein Ra, Rb, R, X1 and X2 are as defined in the disclosure, pharmaceutical compositions comprising said compounds, processes for making and methods of using the same are provided.
摘要翻译: 式(I)化合物:其中Ra,Rb,R,X1和X2如本公开所定义,提供包含所述化合物的药物组合物,制备方法和使用方法。
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2.Novel Cyclic Urea Derivatives, Preparation Thereof and Pharmaceutical Use Thereof as Kinase Inhibitors 有权
标题翻译: 新型环状尿素衍生物,其制备方法及其药物用途作为激酶抑制剂公开(公告)号:US20090082379A1
公开(公告)日:2009-03-26
申请号:US12173380
申请日:2008-07-15
申请人: Frank HALLEY , Youssef El-Ahmad , Victor Certal , Corinne Venot , Anne Dagallier , Hartmut Strobel , Kurt Ritter , Sven Ruf
发明人: Frank HALLEY , Youssef El-Ahmad , Victor Certal , Corinne Venot , Anne Dagallier , Hartmut Strobel , Kurt Ritter , Sven Ruf
IPC分类号: A61K31/506 , C07D401/14 , C07D403/06 , C07D401/06 , C12N5/00 , A61P35/00 , A61K31/444 , C07D403/14 , A61P43/00
CPC分类号: C07D401/14 , C07D401/06 , C07D403/06 , C07D403/14
摘要: Compounds of formula (I): wherein Ra, Rb, R, X1 and X2 are as defined in the disclosure, pharmaceutical compositions comprising said compounds, processes for making and methods of using the same are provided.
摘要翻译: 式(I)化合物:其中Ra,Rb,R,X1和X2如本公开所定义,提供包含所述化合物的药物组合物,制备方法和使用方法。
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