公开(公告)号：US09014991B2

公开(公告)日：2015-04-21

申请号：US13171548

申请日：2011-06-29

申请人： Frederik R. van de Voort ,  David Pinchuk

发明人： Frederik R. van de Voort ,  David Pinchuk

IPC分类号： C11B3/12 ,  G01N21/35 ,  G06F19/00 ,  G01N1/40 ,  G01N21/27 ,  G01N21/3554 ,  G01N21/3577 ,  G01N33/28

CPC分类号： G01N1/4055 ,  C11B3/12 ,  G01N1/4005 ,  G01N21/274 ,  G01N21/3554 ,  G01N21/3577 ,  G01N33/2847 ,  G01N2021/3595 ,  G06F19/00

摘要： A system and method for quantitatively characterizing moisture content of an at least partially hydrophobic fluid sample. The method includes providing a dry solution of an aprotic solvent, adding at least a part of the fluid sample to the solvent to produce an extract-sample, performing infrared spectroscopic testing on the extract-sample to generate absorbance data representing at least one absorbance characteristic of the extracted sample, and generating moisture data for the sample based on the extracted sample data. The system includes a cell for holding and evaluating an extracted sample, an infrared spectrometer for measuring infrared absorbance characteristics of the extracted samples, a computer equipped with software for analyzing data outputted by the infrared spectrometer and utilizing an empirical model to derive at least one calibration equation relating data representing the absorbance characteristics of the extract-sample to unit moisture concentration, and converting the unit moisture concentration to a measure of moisture content of the sample. The method also utilizes D2O to characterize moisture content of the extraction solvent, and compensate for both moisture content of the extraction solvent and matrix effects stemming from miscibility of the hydrophobic fluid in the extraction solvent.

摘要翻译： 一种用于定量表征至少部分疏水的流体样品的水分含量的系统和方法。 该方法包括提供非质子溶剂的干溶液，将至少一部分流体样品加入到溶剂中以产生提取样品，对提取物样品进行红外光谱测试以产生表示至少一种吸光度特征的吸光度数据 并且基于所提取的样本数据生成样本的水分数据。 该系统包括用于保存和评估提取的样品的单元，用于测量提取的样品的红外吸收特性的红外光谱仪，配备有用于分析由红外光谱仪输出的数据的软件的计算机，并利用经验模型来导出至少一个校准 将表示提取物样品的吸收特性的数据与单位水分浓度相关联的方程，并将单位水分浓度转换成样品的水分含量的量度。 该方法还利用D2O来表征提取溶剂的含水量，并补偿萃取溶剂的水分含量和基于疏水性液体在萃取溶剂中的混溶性的基质效应。

公开(公告)号：US20110320135A1

公开(公告)日：2011-12-29

申请号：US13171548

申请日：2011-06-29

申请人： Frederik R. van de Voort ,  David Pinchuk

发明人： Frederik R. van de Voort ,  David Pinchuk

IPC分类号： G01N19/10 ,  G01N7/02

CPC分类号： G01N1/4055 ,  C11B3/12 ,  G01N1/4005 ,  G01N21/274 ,  G01N21/3554 ,  G01N21/3577 ,  G01N33/2847 ,  G01N2021/3595 ,  G06F19/00

摘要： A system and method for quantitatively characterizing moisture content of an at least partially hydrophobic fluid sample. The method includes providing a dry solution of an aprotic solvent, adding at least a part of the fluid sample to the solvent to produce an extract-sample, performing infrared spectroscopic testing on the extract-sample to generate absorbance data representing at least one absorbance characteristic of the extracted sample, and generating moisture data for the sample based on the extracted sample data. The system includes a cell for holding and evaluating an extracted sample, an infrared spectrometer for measuring infrared absorbance characteristics of the extracted samples, a computer equipped with software for analyzing data outputted by the infrared spectrometer and utilizing an empirical model to derive at least one calibration equation relating data representing the absorbance characteristics of the extract-sample to unit moisture concentration, and converting the unit moisture concentration to a measure of moisture content of the sample. The method also utilizes D2O to characterize moisture content of the extraction solvent, and compensate for both moisture content of the extraction solvent and matrix effects stemming from miscibility of the hydrophobic fluid in the extraction solvent.

摘要翻译： 一种用于定量表征至少部分疏水的流体样品的水分含量的系统和方法。 该方法包括提供非质子溶剂的干溶液，将至少一部分流体样品加入到溶剂中以产生提取样品，对提取物样品进行红外光谱测试以产生表示至少一种吸光度特征的吸光度数据 并且基于所提取的样本数据生成样本的水分数据。 该系统包括用于保存和评估提取的样品的单元，用于测量提取的样品的红外吸收特性的红外光谱仪，配备有用于分析由红外光谱仪输出的数据的软件的计算机，并利用经验模型来导出至少一个校准 将表示提取物样品的吸收特性的数据与单位水分浓度相关联的方程，并将单位水分浓度转换成样品的水分含量的量度。 该方法还利用D2O来表征提取溶剂的含水量，并补偿萃取溶剂的水分含量和基于疏水性液体在萃取溶剂中的混溶性的基质效应。

公开(公告)号：US20110318844A1

公开(公告)日：2011-12-29

申请号：US13171566

申请日：2011-06-29

申请人： Frederik R. van de Voort ,  David Pinchuk

发明人： Frederik R. van de Voort ,  David Pinchuk

IPC分类号： G01N31/16

CPC分类号： G01N21/274 ,  G01N21/278 ,  G01N21/3577 ,  G01N31/16 ,  G01N2021/3595

摘要： A system and method of quantitatively characterizing base content of a hydrophobic fluid. The method includes providing a base neutralizing solution including an alcohol (preferably selected from the group consisting of 1-propanol, ethanol, methanol, and mixtures thereof), and mixing the solution with known amounts of a base to produce a number of calibration mixtures. Infrared spectroscopic testing is performed on the calibration mixtures to derive corresponding spectrum data. The spectrum data is processed to solve for a calibration equation that relates a spectral property measurable at a predetermined wavelength to a measure of base concentration per unit volume. The base neutralizing solution is also mixed with the hydrophobic fluid to produce a sample-extract. Infrared spectroscopic testing is performed on the sample-extract to derive corresponding spectrum data. The spectrum data for the sample-extract is processed to measure the spectral property of the calibration equation. The measured spectral property of the sample-extract is input to the calibration equation in order to output a measure of base concentration per unit volume for the sample-extract. A measure of base content of the hydrophobic fluid can be derived from the base concentration per unit volume for the sample-extract. The measure of base content of the hydrophobic fluid sample is derived without splitting of the hydrophobic fluid sample. The system includes a cell for holding and evaluating an extracted sample, an infrared spectrometer for measuring infrared absorption characteristics of the extracted samples, a computer equipped with software for analyzing data outputted by the infrared spectrometer.

摘要翻译： 定量表征疏水性液体的基础含量的系统和方法。 该方法包括提供包含醇（优选选自1-丙醇，乙醇，甲醇及其混合物）的碱的中和溶液，并将该溶液与已知量的碱混合以产生许多校准混合物。 对校准混合物进行红外光谱测试以得到相应的光谱数据。 处理光谱数据以求解将在预定波长可测量的光谱特性与每单位体积的碱浓度的量度相关联的校准方程式。 碱性中和溶液也与疏水性流体混合以产生样品提取物。 对样品提取物进行红外光谱测试以得到相应的光谱数据。 处理样品提取物的光谱数据以测量校准方程的光谱性质。 将样品提取物的测量光谱性质输入到校准方程中，以输出样品提取物的每单位体积的碱浓度的量度。 疏水性液体的碱含量的测量可以从样品提取物的每单位体积的碱浓度得到。 疏水性流体样品的基础含量的测量是在不分裂疏水性液体样品的情况下得到的。 该系统包括用于保存和评估提取的样本的单元，用于测量提取的样本的红外吸收特性的红外光谱仪，配备有用于分析由红外光谱仪输出的数据的软件的计算机。