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公开(公告)号：US20080000828A1
公开(公告)日：2008-01-03
申请号：US10588695
申请日：2005-02-15
申请人： Friedbert Wechs , Arne Gehlen , Bodo Harten , Richard Kruger , Oliver Schuster
发明人： Friedbert Wechs , Arne Gehlen , Bodo Harten , Richard Kruger , Oliver Schuster
IPC分类号： B01D63/02 , B01D39/14 , B01D67/00 , B01D69/00 , B01D69/02 , B01D69/08 , B29C47/00 , B29C47/02
CPC分类号： B01D69/08 , B01D67/0013 , B01D67/0088 , B01D67/0095 , B01D67/0097 , B01D69/02 , B01D71/64 , B01D71/68 , B01D2323/02 , B01D2323/12 , B01D2323/36 , B01D2325/14 , B01D2325/20
摘要： A hydrophilic, semipermeable hollow-fibre membrane for blood treatment, with an integrally asymmetric structure based on a synthetic polymer. The hollow-fibre membrane possesses on its inner surface a porous separating layer and an open-pored supporting layer adjoining the separating layer, and has an ultrafiltration rate in albumin solution of 25 to 60 ml/(h·m2·mmHg). The hollow-fibre membrane is free from pore-stabilising additives, and has a minimum sieving coefficient for cytochrome c of 0.8 and maximum sieving coefficient for albumin of 0.005. Method for the preparation of such membranes based on coagulation induced by a non-solvent, whereby a spinning solution of a synthetic first polymer and possibly a hydrophilic second polymer is extruded into a hollow fibre through the annular slit of a hollow-fibre die with simultaneous extrusion of a coagulation medium as the interior filler through the central opening of the hollow-fibre die, the interior filler initiating coagulation in the interior of the hollow fibre as a result of which a separating layer on the inner surface of the hollow-fibre membrane is formed as well as the membrane structure, the method being characterised in that the interior filler contains a polyelectrolyte with negative fixed charges.
摘要翻译： 用于血液处理的亲水性半透性中空纤维膜，具有基于合成聚合物的整体不对称结构。 中空纤维膜在其内表面具有邻接分离层的多孔分离层和开孔支撑层，并且在白蛋白溶液中的超滤速率为25至60ml /（hm 2 / .mmHg）。 中空纤维膜不含孔稳定添加剂，细胞色素c的筛分系数最小为0.8，白蛋白筛分系数为0.005。 基于由非溶剂引起的凝结制备这种膜的方法，由此将合成的第一聚合物和可能的亲水性第二聚合物的纺丝溶液通过中空纤维模具的环形狭缝挤出成中空纤维，同时 通过中空纤维模头的中心开口挤出凝固介质作为内部填料，内部填料在中空纤维内部引发凝结，由此在中空纤维膜的内表面上形成分离层 形成膜结构，该方法的特征在于内部填充物含有具有负固定电荷的聚电解质。
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2.发明授权公开(公告)号：US07811507B2
公开(公告)日：2010-10-12
申请号：US10588696
申请日：2005-02-15
CPC分类号： B01D71/68 , B01D67/0011 , B01D67/0016 , B01D67/0088 , B01D67/0095 , B01D67/0097 , B01D69/02 , B01D69/08 , B01D2323/02 , B01D2323/12 , B01D2323/36 , B01D2325/14 , B01D2325/20 , Y10T428/2975
摘要： A hydrophilic semipermeable hollow-fibre membrane for blood treatment, with an integrally asymmetric structure based on a synthetic polymer. The hollow-fiber membrane possess on its inner surface a separating layer and an adjoining open-pored supporting layer, and has an ultrafiltration rate in albumin solution of 5 to ≦25 ml/(h·m2·mmHg). The hollow fiber membrane is free from pore-stabilizing additives and has a maximum sieving coefficient for albumin of 0.005 and a sieving coefficient of cytochrome c that satisfies the equation SCcc≧5·10−5·UFRAlb3−0.004·UFRAlb2+0.1081·UFRAlb−0.25.
摘要翻译： 一种用于血液处理的亲水性半透性中空纤维膜，具有基于合成聚合物的整体不对称结构。 中空纤维膜的内表面具有分离层和邻接的开孔支撑层，并且在白蛋白溶液中具有5至＆lt; llE; 25ml /（h·m 2·mmHg）的超滤速率。 中空纤维膜不含孔稳定添加剂，白蛋白的最大筛分系数为0.005，细胞色素c的筛分系数满足公式SCcc≥5·10-5·UFRAlb3-0.004·UFRAlb2 + 0.1081·UFRAlb- 0.25。
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公开(公告)号：US08302781B2
公开(公告)日：2012-11-06
申请号：US10588695
申请日：2005-02-15
CPC分类号： B01D69/08 , B01D67/0013 , B01D67/0088 , B01D67/0095 , B01D67/0097 , B01D69/02 , B01D71/64 , B01D71/68 , B01D2323/02 , B01D2323/12 , B01D2323/36 , B01D2325/14 , B01D2325/20
摘要： A hydrophilic, semipermeable hollow-fiber membrane for blood treatment, with an integrally asymmetric structure based on a synthetic polymer. The hollow-fiber membrane possesses on its inner surface a porous separating layer and an open-pored supporting layer adjoining the separating layer, and has an ultrafiltration rate in albumin solution of 25 to 60 ml/(h·m2·mmHg). The hollow-fiber membrane is free from pore-stabilizing additives, and has a minimum sieving coefficient for cytochrome c of 0.8 and maximum sieving coefficient for albumin of 0.005. Method for the preparation of such membranes based on coagulation induced by a non-solvent, whereby a spinning solution of a synthetic first polymer and possibly a hydrophilic second polymer is extruded into a hollow fiber through the annular slit of a hollow-fiber die with simultaneous extrusion of a coagulation medium as the interior filler through the central opening of the hollow-fiber die, the interior filler initiating coagulation in the interior of the hollow fiber as a result of which a separating layer on the inner surface of the hollow-fiber membrane is formed as well as the membrane structure, the method being characterized in that the interior filler contains a polyelectrolyte with negative fixed charges.
摘要翻译： 用于血液处理的亲水性半透性中空纤维膜，具有基于合成聚合物的整体不对称结构。 中空纤维膜在其内表面具有邻接分离层的多孔分离层和开孔支撑层，并且在白蛋白溶液中的超滤速率为25至60ml /（h·m 2·mmHg）。 中空纤维膜不含孔稳定添加剂，细胞色素c的筛分系数最小为0.8，白蛋白筛分系数为0.005。 基于由非溶剂引起的凝结制备这种膜的方法，由此将合成的第一聚合物和可能的亲水性第二聚合物的纺丝溶液通过中空纤维模具的环形狭缝挤出成中空纤维，同时 通过中空纤维模头的中心开口挤出凝固介质作为内部填料，内部填料在中空纤维内部引发凝结，由此在中空纤维膜的内表面上形成分离层 形成膜结构，该方法的特征在于内部填充物含有具有负固定电荷的聚电解质。
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公开(公告)号：US08651284B2
公开(公告)日：2014-02-18
申请号：US12637268
申请日：2009-12-14
CPC分类号： B01D71/68 , B01D67/0011 , B01D67/0016 , B01D67/0088 , B01D67/0095 , B01D67/0097 , B01D69/02 , B01D69/08 , B01D2323/02 , B01D2323/12 , B01D2323/36 , B01D2325/14 , B01D2325/20 , Y10T428/2975
摘要： A hydrophilic semipermeable hollow-fiber membrane for blood treatment, with an integrally asymmetric structure based on a synthetic polymer. The hollow-fiber membrane possesses on its inner surface a separating layer and an adjoining open-pored supporting layer, and has an ultrafiltration rate in albumin solution of 5 to 25 ml/(h·m2·mmHg). The hollow-fiber membrane is free from pore-stabilizing additives and has a maximum sieving coefficient for albumin of 0.005 and a sieving coefficient for cytochrome c that satisfies the equation SCCC≧5·10−5·UFRAlb3−0.004·UFRAlb2+1.081·UFRAlb−0.25.
摘要翻译： 一种用于血液处理的亲水性半透性中空纤维膜，具有基于合成聚合物的整体不对称结构。 中空纤维膜的内表面具有分离层和相邻的开孔支撑层，并且在白蛋白溶液中具有5至25ml /（h·m 2·mmHg）的超滤速率。 中空纤维膜不含孔稳定添加剂，白蛋白的最大筛分系数为0.005，细胞色素c的筛分系数满足方程式SCCC> = 5·10-5·UFRAlb3-0.004·UFRAlb2 + 1.081· UFRAlb-0.25。
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公开(公告)号：US20100089820A1
公开(公告)日：2010-04-15
申请号：US12637268
申请日：2009-12-14
CPC分类号： B01D71/68 , B01D67/0011 , B01D67/0016 , B01D67/0088 , B01D67/0095 , B01D67/0097 , B01D69/02 , B01D69/08 , B01D2323/02 , B01D2323/12 , B01D2323/36 , B01D2325/14 , B01D2325/20 , Y10T428/2975
摘要： A hydrophilic semipermeable hollow-fibre membrane for blood treatment, with an integrally asymmetric structure based on a synthetic polymer. The hollow-fibre membrane possesses on its inner surface a separating layer and an adjoining open-pored supporting layer, and has an ultrafiltration rate in albumin solution of 5 to 25 ml/(h·m2·mmHg). The hollow-fibre membrane is free from pore-stabilising additives and has a maximum sieving coefficient for albumin of 0.005 and a sieving coefficient for cytochrome c that satisfies the equation SCCC≧5·10−5·UFRAlb3−0.004·UFRAlb2+1.081·UFRAlb−0.25 A method for producing such membranes by a coagulation process induced by a non-solvent, in which a spinning solution comprising a synthetic first polymer and possibly a hydrophilic second polymer is extruded through the annular slit of a hollow-fibre die to give a hollow fibre, and a coagulation medium that initiates coagulation in the interior of the hollow fibre is simultaneously extruded through the central opening of the hollow-fibre die, the coagulation medium initiating coagulation in the interior of the hollow fibre for formation of a separating layer on the inner surface of the hollow fibre and formation of the membrane structure, the method being characterised in that the interior filler contains a polyelectrolyte with negative fixed charges.
摘要翻译： 一种用于血液处理的亲水性半透性中空纤维膜，具有基于合成聚合物的整体不对称结构。 中空纤维膜的内表面具有分离层和相邻的开孔支撑层，并且在白蛋白溶液中具有5至25ml /（h·m 2·mmHg）的超滤速率。 中空纤维膜没有孔稳定添加剂，白蛋白的最大筛分系数为0.005，细胞色素c的筛分系数满足方程式SCCC≥5·10-5·UFRAlb3-0.004·UFRAlb2 + 1.081·UFRAlb -0.25通过由非溶剂诱导的凝结过程制造这种膜的方法，其中包含合成的第一聚合物和可能的亲水性第二聚合物的纺丝溶液通过中空纤维模头的环形狭缝挤出，得到 中空纤维和在中空纤维内部引起凝结的凝固介质同时挤出通过中空纤维模头的中心开口，凝固介质在中空纤维内部起始凝结以形成分离层， 中空纤维的内表面和膜结构的形成，其特征在于，内部填料含有具有n的聚电解质 特惠固定费用。
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6.发明申请Electronic control device of an electrical drive system with redundant disconnection device 有权具有冗余断路装置的电力驱动系统的电子控制装置公开(公告)号：US20090091285A1
公开(公告)日：2009-04-09
申请号：US12227479
申请日：2007-04-12
申请人： Ulrich Hahn , Richard Kruger , Rolf-Dieter Pavlik
发明人： Ulrich Hahn , Richard Kruger , Rolf-Dieter Pavlik
IPC分类号： G05B19/4063 , G05B9/02
CPC分类号： G05B23/0289 , G05B9/02 , G05B19/4063 , G05B2219/34454 , G05B2219/34465
摘要： In normal mode, a central unit of an electronic control device receives desired and actual values for determining desired current values which are transmitted to an electronic drive unit. The central unit of the electronic drive unit receives the desired current values for determining drive signals for circuit breakers. In monitoring mode, the central unit of the electronic control device checks whether an connected electric motor is in a safe state. If not, the control device transmits disconnection signals to a disconnection device and to the drive unit. The central unit of the electronic control device generates checking information for the drive unit. In the monitoring mode, the central unit of the drive unit checks whether a disconnection signal is transmitted to the central unit and whether the checking information is correct.
摘要翻译： 在正常模式下，电子控制装置的中央单元接收用于确定发送到电子驱动单元的期望电流值的期望值和实际值。 电子驱动单元的中央单元接收用于确定断路器的驱动信号的期望电流值。 在监视模式下，电子控制装置的中央单元检查连接的电动机是否处于安全状态。 如果不是，则控制装置向断开装置和驱动单元发送断开信号。 电子控制装置的中央单元生成驱动单元的检查信息。 在监视模式下，驱动单元的中央单元检查断开信号是否发送到中央单元，以及检查信息是否正确。
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