公开(公告)号：US20210403449A1

公开(公告)日：2021-12-30

申请号：US17468447

申请日：2021-09-07

Applicant: Fudan University

Inventor： Fener CHEN ,  Chunlin ZHUANG ,  Li DING

IPC: C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D401/14 ,  C07D239/48 ,  A61P31/18

Abstract: This application provides a biphenyl diaryl pyrimidine derivative with an aromatic heterocyclic structure, a pharmaceutically-acceptable salt, a stereoisomer, a hydrate and a solvate thereof, where the biphenyl diaryl pyrimidine derivative is shown in formula (I). This application also provides a pharmaceutical composition containing the biphenyl diaryl pyrimidine derivative, or a pharmaceutically-acceptable salt, a stereoisomer, a hydrate and a solvate thereof, and a pharmaceutically-acceptable carrier. This application further provides a method of treating AIDS by administering a therapeutically effective amount of the pharmaceutical composition to a patient in need.

公开(公告)号：US20160049287A1

公开(公告)日：2016-02-18

申请号：US14829454

申请日：2015-08-18

Applicant: FUDAN UNIVERSITY

Inventor： Chuanfan DING ,  Li DING

IPC: H01J49/42 ,  H01J49/06

CPC classification number: H01J49/4225 ,  H01J49/004 ,  H01J49/065 ,  H01J49/4235

Abstract: The invention “Ion Trap Array (ITA)” pertains generally to the field of ion storage and analysis technologies, and particularly to the ion storing apparatus and mass spectrometry instruments which separate ions by its character such as mass-to-charge ratio. The aim of this invention is providing an apparatus for ion storage and analysis comprising at least two or more rows of parallel placed electrode array wherein each electrode array includes at least two or more parallel bar-shaped electrodes, by applying different phase of alternating current voltages on different bar electrodes to create alternating electric fields inside the space between two parallel electrodes of different rows of electrode arrays, multiple linear ion trapping fields paralleled constructed in the space between the different rows of electrode arrays which are open to adjacent each other without a real barrier. This invention also provides a method for ion storage and analysis involving with the trapping, cooling and mass-selected analyzing of ions by this apparatus mentioned which constructs multiple conjoint linear ion trapping fields in the space between the different rows of electrode arrays

Abstract translation: 本发明“离子阱阵列（ITA）”一般涉及离子存储和分析技术领域，特别涉及离子存储装置和质谱仪器，它们通过诸如质荷比的特性分离离子。 本发明的目的是提供一种用于离子存储和分析的装置，其包括至少两行或多行平行放置的电极阵列，其中每个电极阵列包括至少两个或更多个平行的棒状电极，通过施加不同相位的交流电压 在不同的棒电极上在不同行电极阵列的两个平行电极之间的空间内部产生交替电场，多个线性离子俘获场平行地构造在电极阵列的不同行之间的空间中，这些空间彼此相邻而没有实际 屏障。 本发明还提供一种离子存储和分析的方法，其涉及通过所述装置进行的捕获，冷却和质量选择的离子分析，其构造了在不同行电极阵列之间的空间中的多个联合线性离子捕获场