公开(公告)号：US20180127459A1

公开(公告)日：2018-05-10

申请号：US15564224

申请日：2016-04-04

Applicant: GE HEALTHCARE BIOPROCESS R&D AB

Inventor： Martin Hall ,  Mikael Berg ,  Ida Eklind ,  Sandeep Kristiansson

IPC: C07K1/18 ,  C07K14/755 ,  A61P7/00 ,  B01D15/36

CPC classification number: C07K1/18 ,  A61K38/00 ,  A61P7/00 ,  B01D15/363 ,  C07K14/755

Abstract: The present invention relates to the field of chromatography. More closely, the invention relates to a chromatographic method for purification of Factor VIII and von Willebrand factor from a cryoprecipitate of plasma. The chromatographic method is performed on a matrix comprising an inner porous core and outer porous lid surrounding said core.