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公开(公告)号：US09969761B2
公开(公告)日：2018-05-15
申请号：US14258247
申请日：2014-04-22
摘要： The present invention relates to a method for improving stability of non fluoridated sugar derivatives, and in particular glucose derivatives such as 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-β-D-mannopyranose which are used as precursors for production of radiofluoridated sugar derivatives for use in in vivo imaging procedures such as positron emission tomography (PET). The method comprises storing the non fluoridated sugar derivative in an organic solvent. The resultant formulations of the non fluoridated sugar derivative and cassettes for automated synthesis apparatus comprising the same are also claimed.
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公开(公告)号：US10134496B2
公开(公告)日：2018-11-20
申请号：US15104373
申请日：2014-12-19
摘要： Methods and devices for directing a waste fluid from a radiopharmaceutical synthesis system to a waste vessel are provided. In one example, the method includes serially connecting a primary waste vessel to a secondary waste vessel with a fluid conduit, including a waste valve connected to the fluid conduit extending between the primary waste vessel and secondary waste vessel; opening the waste valve so as to allow fluid communication between cavities of the primary and secondary waste vessels; drawing a low pressure in both waste vessels; closing the waste valve so as to fluidically isolate the secondary waste vessel from the primary waste vessel, discharging the waste fluid through a pump valve into the primary waste vessel, and opening the waste valve to evacuate the waste fluid from the primary waste vessel into the secondary waste vessel.
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公开(公告)号：US20160314866A1
公开(公告)日：2016-10-27
申请号：US15104373
申请日：2014-12-19
摘要： The present invention relates to methods and devices for evacuating the contents of a primary waste vessel to a secondary waste vessel, desirably between production runs of an automated synthesis device.
摘要翻译： 本发明涉及用于将主废料容器的内容物抽出到二次废料容器的方法和装置，理想地在自动合成装置的生产运行之间。
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