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公开(公告)号：US10731118B2
公开(公告)日：2020-08-04
申请号：US15363562
申请日：2016-11-29
Applicant: GE Healthcare Bio-Sciences AB
Inventor： Ralph Stankowski , Asa Lundstrom , Andreas Castan , Michael Miller , Yvette Klingberg
Abstract: Provided is a bioreactor assembly that includes a plurality of cultivation bags at least one flexible temperature control bag having a thermostating fluid, and a tray adapted to rock back and forth around at least one axis. The flexible temperature control bag is mounted on the tray and the cultivation bags are located on the flexible temperature control bag.
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公开(公告)号：US20170073624A1
公开(公告)日：2017-03-16
申请号：US15363562
申请日：2016-11-29
Applicant: GE Healthcare Bio-Sciences AB
Inventor： Ralph Stankowski , Asa Lundstrom , Andreas Castan , Michael Miller , Yvette Klingberg
Abstract: The invention discloses a bioreactor assembly comprising: a) a plurality of cultivation bags; b) at least one flexible temperature control bag comprising a thermostating fluid, and; c) a tray adapted to rock back and forth around at least one axis, wherein the flexible temperature control bag is mounted on the tray and the cultivation bags are located on the flexible temperature control bag.
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Patent Agency Ranking
公开(公告)号：US10450540B2
公开(公告)日：2019-10-22
申请号：US15306691
申请日：2015-04-27
Applicant: GE Healthcare Bio-Sciences AB
Inventor： Klaus Gebauer , Andreas Castan , Camilla Estmer-Nilsson , Thomas Falkman , Anders Wilen , Michael Miller , Ralph Stankowski
Abstract: The invention discloses a flexible bag assembly for cultivation of cells, comprising one or more bags forming a plurality of cultivation compartments, wherein a drain port in at least a first cultivation compartment is adapted to be fluidically connected with a second cultivation compartment upon opening of a valve means. It also discloses a bioreactor with the bag assembly mounted on a rocking tray and a method of cultivating cells in the assembly.
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公开(公告)号：US20170044477A1
公开(公告)日：2017-02-16
申请号：US15306691
申请日：2015-04-27
Applicant: GE Healthcare Bio-Sciences AB
Inventor： Klaus Gebauer , Andreas Castan , Camilla Estmer-Nilsson , Thomas Falkman , Anders Wilen , Michael Miller , Ralph Stankowski
CPC classification number: C12M23/14 , C12M23/26 , C12M23/34 , C12M23/58 , C12M27/16 , C12M41/24 , C12Q3/00
Abstract: The invention discloses a flexible bag assembly for cultivation of cells, comprising one or more bags forming a plurality of cultivation compartments, wherein a drain port in at least a first cultivation compartment is adapted to be fluidically connected with a second cultivation compartment upon opening of a valve means. It also discloses a bioreactor with the bag assembly mounted on a rocking tray and a method of cultivating cells in the assembly.
Abstract translation: 本发明公开了一种用于培养细胞的柔性袋组件，包括形成多个培养隔室的一个或多个袋，其中至少第一栽培室中的排出口适于在打开第二培养室时与第二培养室流体连接 阀门装置。 它还公开了一种生物反应器，其中袋组件安装在摆动托盘上，以及在组件中培养细胞的方法。
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公开(公告)号：US20180346864A1
公开(公告)日：2018-12-06
申请号：US15760022
申请日：2016-09-12
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor： Eric Faldt , Ralph Stankowski
Abstract: A filter holding device (1; 41; 75; 81) arranged for providing at least one filter (7; 43a, 43b; 85) inside a flexible bag (3; 71), said filter holding device comprising attaching means (19a-d, 21a-d; 79; 83) for attaching the filter holding device to an inner surface of the flexible bag such that the at least one filter held by the filter holding device is provided at a distance from the inner surface of the flexible bag.
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公开(公告)号：US20170183127A1
公开(公告)日：2017-06-29
申请号：US15313467
申请日：2015-06-10
Applicant: GE Healthcare Bio-Sciences AB
Inventor： Ralph Stankowski , Michael Miller
CPC classification number: B65D31/10 , B65D33/02 , B65D33/16 , B65D75/008
Abstract: The invention discloses a plastic bag comprising: at least one longitudinal end weld (112), wherein the end weld comprises an elongate transversely-oriented weld (114) bounded by a first pair (116) and a second pair (118) of coterminous oblique welds (116a, 116b, 118a, 118b) extending along an oblique angle from the first (114a) and second (114b) ends of transversely-oriented weld (114), respectively, such that each pair of oblique welds (116a, 116b, 118a, 118b) forms a first (120a) and second (120b) apex, respectively, adjacent its respective end (114a, 114b) of the transversely-oriented weld (114), a first (122) and second (124) planar gusset attached to the bag (110) along or within the first (116a, 116b) and second (118a, 118b) pair of oblique welds so as to overlie the first (120a) and second (120b) apex, respectively.
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公开(公告)号：US20200087605A1
公开(公告)日：2020-03-19
申请号：US16586272
申请日：2019-09-27
Applicant: GE Healthcare Bio-Sciences AB
Inventor： Klaus Gebauer , Andreas Castan , Camilla Estmer-Nilsson , Thomas Falkman , Anders Wilen , Michael Miller , Ralph Stankowski
Abstract: The invention discloses a flexible bag assembly for cultivation of cells, comprising one or more bags forming a plurality of cultivation compartments, wherein a drain port in at least a first cultivation compartment is adapted to be fluidically connected with a second cultivation compartment upon opening of a valve means. It also discloses a bioreactor with the bag assembly mounted on a rocking tray and a method of cultivating cells in the assembly.
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