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公开(公告)号:US10760041B2
公开(公告)日:2020-09-01
申请号:US14915808
申请日:2014-08-27
Applicant: GE Healthcare Bio-Sciences AB
Inventor: Karl Liderfelt , Eric Faldt , Andreas Castan
Abstract: The invention discloses a flexible bag for cell cultivation, comprising a cultivation compartment and at least one dialysis compartment, wherein the dialysis compartment(s) is/are delimited from the cultivation compartment by one or more dialysis membranes and is/are fluidically connected to a first and a second port in the bag.
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公开(公告)号:US20150061282A1
公开(公告)日:2015-03-05
申请号:US14385307
申请日:2013-03-25
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor: Eric Faldt , Klaus Gebauer
CPC classification number: A61M39/105 , A61M39/16 , A61M39/18 , F16L39/00 , F16L2201/44
Abstract: The invention relates to a An aseptic connector comprising a first connection unit (102; 202; 302; 402; 502) provided with a first terminal end surface (104; 204; 304; 404; 504) and a second connection unit (106; 206; 306; 406; 506) provided with a second terminal end surface (108; 208; 308; 408; 508); said first and second terminal end surfaces are each provided with at least one first and second opening (110, 112; 210, 212; 310, 312; 410, 412; 510, 512), which openings are orientated to substantially coincide when said first and second connection units are connected to each other; said first and second openings are sealed by at least one film (114; 214; 314; 414; 514) arranged on said first and second connection units, so that the contact between the film and each connection unit is aseptic; said at least one film is adapted to be mated with a corresponding film on the other connection unit when said first and second connection units are connected to each other; and said mated films are adapted to be pulled out together two and two after mating such that corresponding first and second openings in said first and second terminal end surfaces are mated aseptically. At least two first ports (116; 216; 316; 416; 516) are arranged on the first connection unit, which first ports have fluid connection with the at least one first opening (110; 210; 310; 410; 510) in the first terminal end surface; and in that at least one second port (118; 218; 318; 418; 518) is arranged on the second connection unit, which the at least one second port has a fluid connection with the at least one second opening (112; 212; 312; 412; 512) in the second terminal end surface.
Abstract translation: 本发明涉及一种无菌连接器,包括设置有第一终端表面(104; 204; 304; 404; 504)的第一连接单元(102; 202; 402; 502)和第二连接单元(106; 设置有第二终端表面(108; 208; 308; 408; 508); 所述第一和第二终端表面各自设置有至少一个第一和第二开口(110,112; 210,212; 310,312; 410,412; 510,512),当所述第一和第二开口 并且第二连接单元彼此连接; 所述第一和第二开口由布置在所述第一和第二连接单元上的至少一个薄膜(114; 214; 314; 414; 514)密封,使得薄膜和每个连接单元之间的接触是无菌的; 当所述第一和第二连接单元彼此连接时,所述至少一个胶片适于与另一连接单元上的相应胶片配合; 并且所述配合膜适于在配合之后一两个地拉出,使得所述第一和第二终端表面中的对应的第一和第二开口被无菌地配合。 至少两个第一端口(116; 216; 316; 416; 516)被布置在所述第一连接单元上,所述第一端口具有与所述第一端口中的所述至少一个第一开口(110; 210; 310; 410; 510) 第一终端面; 并且至少一个第二端口(118; 218; 318; 418; 518)布置在所述第二连接单元上,所述至少一个第二端口具有与所述至少一个第二开口(112; 212; 312; 412; 512)。
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公开(公告)号:US20180346864A1
公开(公告)日:2018-12-06
申请号:US15760022
申请日:2016-09-12
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor: Eric Faldt , Ralph Stankowski
Abstract: A filter holding device (1; 41; 75; 81) arranged for providing at least one filter (7; 43a, 43b; 85) inside a flexible bag (3; 71), said filter holding device comprising attaching means (19a-d, 21a-d; 79; 83) for attaching the filter holding device to an inner surface of the flexible bag such that the at least one filter held by the filter holding device is provided at a distance from the inner surface of the flexible bag.
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公开(公告)号:US20170281921A1
公开(公告)日:2017-10-05
申请号:US15625401
申请日:2017-06-16
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor: Eric Faldt , Klaus Gebauer
CPC classification number: A61M39/105 , A61M39/16 , A61M39/18 , F16L39/00 , F16L2201/44
Abstract: The invention relates to a An aseptic connector comprising a first connection unit (102; 202; 302; 402; 502) provided with a first terminal end surface (104; 204; 304; 404; 504) and a second connection unit (106; 206; 306; 406; 506) provided with a second terminal end surface (108; 208; 308; 408; 508); said first and second terminal end surfaces are each provided with at least one first and second opening (110, 112; 210, 212; 310, 312; 410, 412; 510, 512), which openings are orientated to substantially coincide when said first and second connection units are connected to each other; said first and second openings are sealed by at least one film (114; 214; 314; 414; 514) arranged on said first and second connection units, so that the contact between the film and each connection unit is aseptic; said at least one film is adapted to be mated with a corresponding film on the other connection unit when said first and second connection units are connected to each other; and said mated films are adapted to be pulled out together two and two after mating such that corresponding first and second openings in said first and second terminal end surfaces are mated aseptically. At least two first ports (116; 216; 316; 416; 516) are arranged on the first connection unit, which first ports have fluid connection with the at least one first opening (110; 210; 310; 410; 510) in the first terminal end surface; and in that at least one second port (118; 218; 318; 418; 518) is arranged on the second connection unit, which the at least one second port has a fluid connection with the at least one second opening (112; 212; 312; 412; 512) in the second terminal end surface.
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公开(公告)号:US20170013825A1
公开(公告)日:2017-01-19
申请号:US15125871
申请日:2015-02-19
Applicant: GE Healthcare Bio-Sciences AB
Inventor: Eric Faldt
CPC classification number: A01N1/021 , A01N1/0268 , B01L3/50825 , B01L2200/141 , B01L2300/042 , B01L2300/044 , B01L2300/0832 , F25D3/08 , F25D2303/0842 , G01N1/42
Abstract: The present invention relates to a product and method for cell preservation, such as cell banking of any type of cells for subsequent scientific or medical use. More closely, the invention relates to a product and a method for cryopreservation of cells using vacuum tubes provided with freeze media/cryopreservation liquid.
Abstract translation: 本发明涉及用于细胞保存的产品和方法,例如用于随后的科学或医学用途的任何类型的细胞的细胞库。 更详细地说,本发明涉及使用提供有冷冻介质/冷冻保存液体的真空管冷冻保存细胞的产品和方法。
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公开(公告)号:US20150041009A1
公开(公告)日:2015-02-12
申请号:US14385516
申请日:2013-03-28
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor: Klaus Gebauer , Ekta Mahajan , Eric Faldt
IPC: F16K11/10
CPC classification number: F16K11/10 , A61M5/1408 , A61M2039/242 , B01D15/14 , F16K15/144 , F16K15/145 , F16K15/148 , F16K27/0209 , Y10T137/7838 , Y10T137/789 , Y10T137/87684 , G01N2030/328 , G01N2030/6056
Abstract: The present invention relates to a device (1) for delivery of fluid, said device comprising at least two fluid ducts (12-17) of flexible material, each of which in one end can be connected to a fluid source and in the opposite end is connected to a manifold (18) having an inlet end and an outlet end, each of said fluid ducts (12-17) comprising a pinch valve (19) for closing and opening the duct. According to the invention a check valve (20) is disposed in at least one of said fluid ducts (12-17) in the end thereof connected to the manifold (18).
Abstract translation: 本发明涉及一种用于输送流体的装置(1),所述装置包括至少两个柔性材料的流体管道(12-17),每个流体管道的一端可以连接到流体源并且在相对端 连接到具有入口端和出口端的歧管(18),每个所述流体管道(12-17)包括用于关闭和打开管道的夹紧阀(19)。 根据本发明,止回阀(20)设置在连接到歧管(18)的端部中的至少一个所述流体管道(12-17)中。
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公开(公告)号:US11846635B2
公开(公告)日:2023-12-19
申请号:US16470677
申请日:2017-12-21
Applicant: GE Healthcare Bio-Sciences AB
Inventor: Ola Lind , Klaus Gebauer , Eric Faldt , Nils Norrman , Ronnie Palmgren , Jesper Hedberg , Niklas Jungnelius , Karl Liderfelt , Anita Solbrand
IPC: G01N33/543 , C12M3/00 , C12M3/06 , C12M1/00 , C12M1/34 , C12N13/00 , B03C5/00 , B03C5/02 , B01D21/00 , B03C1/30 , B03C1/01 , B03C1/28
CPC classification number: G01N33/54326 , B01D21/0009 , B03C1/30 , B03C5/00 , B03C5/02 , C12M23/48 , C12M27/16 , C12M29/00 , C12M41/44 , C12M45/07 , C12M47/04 , C12M47/10 , C12N13/00 , G01N33/5436 , B03C1/01 , B03C1/288 , B03C2201/26 , G01N2333/31
Abstract: The invention discloses an immunoglobulin-binding magnetic bead, comprising a porous matrix and one or more magnetic particles embedded in said matrix, wherein said matrix comprises a porous polymer and at least 10 mg/ml Fc-binding proteinaceous ligands covalently coupled to said porous polymer.
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公开(公告)号:US10094481B2
公开(公告)日:2018-10-09
申请号:US14385516
申请日:2013-03-28
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor: Klaus Gebauer , Ekta Mahajan , Eric Faldt
Abstract: The present invention relates to a device (1) for delivery of fluid, said device comprising at least two fluid ducts (12-17) of flexible material, each of which in one end can be connected to a fluid source and in the opposite end is connected to a manifold (18) having an inlet end and an outlet end, each of said fluid ducts (12-17) comprising a pinch valve (19) for closing and opening the duct. According to the invention a check valve (20) is disposed in at least one of said fluid ducts (12-17) in the end thereof connected to the manifold (18).
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公开(公告)号:US20160194589A1
公开(公告)日:2016-07-07
申请号:US14915808
申请日:2014-08-27
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor: Karl Liderfelt , Eric Faldt , Andreas CASTAN
IPC: C12M1/00
CPC classification number: C12M23/14 , B01D63/02 , B01D2313/20 , C12M23/26 , C12M23/34 , C12M29/04 , C12M29/16
Abstract: The invention discloses a flexible bag for cell cultivation, comprising a cultivation compartment and at least one dialysis compartment, wherein the dialysis compartment(s) is/are delimited from the cultivation compartment by one or more dialysis membranes and is/are fluidically connected to a first and a second port in the bag.
Abstract translation: 本发明公开了一种用于细胞培养的柔性袋,包括培养室和至少一个透析室,其中透析室通过一个或多个透析膜与培养室隔开,并且流体连接到 第一个和第二个口袋在袋子里。
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公开(公告)号:US20190339261A1
公开(公告)日:2019-11-07
申请号:US16470677
申请日:2017-12-21
Applicant: GE Healthcare Bio-Sciences AB
Inventor: Ola Lind , Klaus Gebauer , Eric Faldt , Nils Norrman , Ronnie Palmgren , Jesper Hedberg , Niklas Jungnelius , Karl Liderfelt , Anita Solbrand
IPC: G01N33/543 , C12M1/00 , C12M3/00 , C12M3/06 , C12M1/34
Abstract: The invention discloses an immunoglobulin-binding magnetic bead, comprising a porous matrix and one or more magnetic particles embedded in said matrix, wherein said matrix comprises a porous polymer and at least 10 mg/ml Fc-binding proteinaceous ligands covalently coupled to said porous polymer.
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