公开(公告)号：US20210002669A1

公开(公告)日：2021-01-07

申请号：US16956942

申请日：2018-12-21

Applicant: GENENTECH, INC.

Inventor： Chi Kin Domingos Ng ,  Yongping Guo Crawford ,  Amy Shen ,  Meixia Zhou ,  Bradley R. Snedecor ,  Shahram Misaghi ,  Albert Eric Gao

IPC: C12N15/90 ,  C07K16/00

Abstract: The presently disclosed subject matter relates to targeted integration (TI) host cells suitable for the expression of recombinant proteins, as well as methods of producing and using said TI host cells.

公开(公告)号：US12129480B2

公开(公告)日：2024-10-29

申请号：US16956942

申请日：2018-12-21

Applicant: GENENTECH, INC.

Inventor： Chi Kin Domingos Ng ,  Yongping Guo Crawford ,  Amy Shen ,  Meixia Zhou ,  Bradley R. Snedecor ,  Shahram Misaghi ,  Albert Eric Gao

IPC: C12N15/90 ,  C07K16/00

CPC classification number: C12N15/907 ,  C07K16/00 ,  C12N15/90 ,  C07K2317/51 ,  C07K2317/515 ,  C12N2800/30 ,  C12N2800/90 ,  C12N2840/00

Abstract: The presently disclosed subject matter relates to targeted integration (TI) host cells suitable for the expression of recombinant proteins, as well as methods of producing and using said TI host cells.