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公开(公告)号：US11725050B2
公开(公告)日：2023-08-15
申请号：US16903300
申请日：2020-06-16
申请人： Genentech, Inc.
发明人： Philip E. Hass , Meredith Hazen , Yi-Chun Hsiao , Rajita Khosla , Gerald R. Nakamura , Dhaya Seshasayee , Menno Van Lookeren Campagne , Hongkang Xi , Wenwu Zhai , Jack Bevers, III , Nancy Chiang
CPC分类号： C07K16/244 , A61K39/3955 , C07K16/22 , C07K16/40 , C12N15/63 , A61K2039/507 , C07K2317/14 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/53 , C07K2317/54 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要： The invention provides interleukin-33 (IL-33) antibodies and methods of using the same.
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2.发明授权公开(公告)号：US11136365B2
公开(公告)日：2021-10-05
申请号：US16196823
申请日：2018-11-20
申请人： Genentech, Inc.
发明人： Justin Scheer , Wenjun Ouyang , Richard Vandlen , Philip E. Hass , Eric Gary Stefanich , Ganesh A. Kolumam , Xiaoting Wang , Jed Ross , Nicholas Van Bruggen
摘要： The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号：US10093730B2
公开(公告)日：2018-10-09
申请号：US14937778
申请日：2015-11-10
申请人： Genentech, Inc.
发明人： Philip E. Hass , Meredith Hazen , Yi-Chun Hsiao , Rajita Khosla , Gerald R. Nakamura , Dhaya Seshasayee , Menno Van Lookeren Campagne , Hongkang Xi , Wenwu Zhai , Jack Bevers, III , Nancy Chiang
摘要： The invention provides interleukin-33 (IL-33) antibodies and methods of using the same.
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公开(公告)号：US10087227B2
公开(公告)日：2018-10-02
申请号：US15369236
申请日：2016-12-05
申请人： Genentech, Inc.
发明人： Justin Scheer , Wenjun Ouyang , Richard Vandlen , Philip E. Hass , Eric Gary Stefanich , Xiaoting Wang
摘要： The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号：US11999787B2
公开(公告)日：2024-06-04
申请号：US17208292
申请日：2021-03-22
申请人： Genentech, Inc.
发明人： Minhong Yan , Gu Zhang , Nicholas John Agard , Danielle Marie Dicara , Philip E. Hass , Julie Q. Hang , Erin L. Christensen , Robert Paul Morse , Sarah Sanowar , Vittal Shivva
IPC分类号： C07K16/28 , A61K9/00 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/60 , A61K47/68 , A61P27/02
CPC分类号： C07K16/2863 , A61K9/0048 , A61K39/3955 , A61K45/06 , A61K47/60 , A61K47/6849 , A61P27/02 , A61K2039/505 , A61K2039/54 , C07K2317/24 , C07K2317/55 , C07K2317/565 , C07K2317/75 , C07K2317/92
摘要： The invention provides Tie-2 antibodies and fragments thereof and conjugates and methods of using the same.
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公开(公告)号：US10723795B2
公开(公告)日：2020-07-28
申请号：US16119667
申请日：2018-08-31
申请人： Genentech, Inc.
发明人： Philip E. Hass , Meredith Hazen , Yi-Chun Hsiao , Rajita Khosla , Gerald R. Nakamura , Dhaya Seshasayee , Menno Van Lookeren Campagne , Hongkang Xi , Wenwu Zhai , Jack Bevers, III , Nancy Chiang
摘要： The invention provides interleukin-33 (IL-33) antibodies and methods of using the same.
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公开(公告)号：US10584155B2
公开(公告)日：2020-03-10
申请号：US15801867
申请日：2017-11-02
申请人： Genentech, Inc.
发明人： Justin Scheer , Wenjun Ouyang , Richard Vandlen , Philip E. Hass , Eric Gary Stefanich , Ganesh A. Kolumam , Xiaoting Wang , Jed Ross , Nicholas Van Bruggen , Wyne P. Lee
摘要： The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号：US20190177387A1
公开(公告)日：2019-06-13
申请号：US16196743
申请日：2018-11-20
申请人： Genentech, Inc.
发明人： Justin Scheer , Wenjun Ouyang , Richard Vandlen , Philip E. Hass , Eric Gary Stefanich , Ganesh A. Kolumam , Xiaoting Wang , Jed Ross , Nicholas Van Bruggen , Wyne P. Lee
摘要： The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号：US10160793B2
公开(公告)日：2018-12-25
申请号：US14214161
申请日：2014-03-14
申请人： Genentech, Inc.
发明人： Justin Scheer , Wenjun Ouyang , Richard Vandlen , Philip E. Hass , Eric Gary Stefanich , Xiaoting Wang
摘要： The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.
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公开(公告)号：US20240327528A1
公开(公告)日：2024-10-03
申请号：US18609758
申请日：2024-03-19
申请人： Genentech, Inc.
发明人： Minhong Yan , Gu Zhang , Nicholas John Agard , Danielle Marie DiCara , Philip E. Hass , Julie Q. Hang , Erin L. Christensen , Robert Paul Morse , Sarah Sanowar , Vittal Shivva
IPC分类号： C07K16/28 , A61K9/00 , A61K39/00 , A61K39/395 , A61K45/06 , A61K47/60 , A61K47/68 , A61P27/02
CPC分类号： C07K16/2863 , A61K9/0048 , A61K39/3955 , A61K45/06 , A61K47/60 , A61K47/6849 , A61P27/02 , A61K2039/505 , A61K2039/54 , C07K2317/24 , C07K2317/55 , C07K2317/565 , C07K2317/75 , C07K2317/92
摘要： The invention provides Tie-2 antibodies and fragments thereof and conjugates and methods of using the same.
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