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公开(公告)号:US20190169667A1
公开(公告)日:2019-06-06
申请号:US16185369
申请日:2018-11-09
Applicant: GENENTECH, INC.
Inventor: Martin GAWLITZEK , Sven MARKERT , Oliver POPP , Masaru Ken SHIRATORI , Thomas TROEBS , Jessica WUU
Abstract: Provided herein are cell culture media and methods culturing host cells expressing polypeptides to reduce the level of trisulfide bonds in polypeptides produced by the host cells.