专利检索 ap:("GLAXO LAB LTD") AND inv:"ELKS J" 第 1 页

1.

发明授权
Novel process for the preparation of 17a-hydroxy-pregna-1,4,9(11)-triene-3,20-dione 失效
标题翻译：制备17A-羟基-PREGNA-1,4,9（11） - 三烯-3,20-二酮的新方法

公开(公告)号：US3715376A

公开(公告)日：1973-02-06

申请号：US3715376D

申请日：1970-05-25

申请人： GLAXO LAB LTD

发明人： ELKS J

IPC分类号： C07J5/00 , C07J75/00 , C07C169/32

CPC分类号： C07J5/00 , C07J75/00

摘要： This invention relates to a novel intermediate in the synthesis of steroids having hormonal activity and to processes for its preparation and further conversion.

摘要翻译： 本发明涉及具有激素活性的类固醇合成中的新中间体及其制备和进一步转化的方法。

2.

发明授权
21-phosphate esters of 17{60 -acyloxy-21 hydroxy steroids of the pregnane series 失效
标题翻译： 17种{60-氨基-21羟基类抗坏血酸类抗生素的21-磷酸酯

公开(公告)号：US3764616A

公开(公告)日：1973-10-09

申请号：US3764616D

申请日：1969-10-14

申请人： GLAXO LAB LTD

发明人： ELKS J , MAY P , PHILLIPPS G

IPC分类号： C07J51/00 , A61K31/573 , B23D33/00 , C07J5/00 , C07C169/30

CPC分类号： A61K31/573 , A61K9/0014 , A61K9/0043 , A61K9/0046 , A61K9/2018 , B23D33/00 , C07J5/00

摘要： This invention is concerned with novel 21-phosphate esters of 17 Alpha -acyloxy-21-hydroxy steroids of the pregane series and with methods of preparing such compounds. The compounds are useful as topical anti-inflamatory agents.

摘要翻译： 本发明涉及先天系列的17种α-酰氧基-21-羟基类固醇的新型21-磷酸酯及其制备方法。该化合物可用作局部抗炎剂。

3.

发明授权
Preparation of cephalosporins having a substituted methyl group at position-3 by reaction of a 3-halomethyl cephalosporin with an onium salt 失效
标题翻译：通过反应具有盐酸盐的3-甲基甲硅烷氧基磷酰胺在位置-3处制备具有取代的甲基的CEPHOROSPORIN

公开(公告)号：US3833572A

公开(公告)日：1974-09-03

申请号：US21985872

申请日：1972-01-21

申请人： GLAXO LAB LTD

发明人： CLARK J , ELKS J

IPC分类号： A61K31/545 , C07D501/04 , C07D501/14 , C07D501/24 , C07D99/24

CPC分类号： C07D501/04

摘要： A PROCESS FOR PREPARING CEPHALOSPORIN COMPOUNDS HAVING A SUBSTITUTED METHYL GROUP AT THE 3-POSITION WHICH COMPRISES REACTING A CORRESPONDING CEPHALOSPORIN COMPOUND HAVING A DIFFERENT SUBSTITUTED METHYL GROUP AT THE 3-POSITION WITH AN ONIUM SALT CORRESPONDING TO THE MEDIA, THE ANION OF THE ONIUM SALT CORRESPONDING TO THE DESIRED METHYL SUBSTITUENT.

4.

发明授权
3-keto-delta 4-9alpha-halo-11-oxygenated-16-methyl or methylene-17alpha-acyloxy-20-keto-21-halo pregnenes 失效
标题翻译： 3-乙酸乙酯4-9ALPHA-HALO-11-氧化-16-甲基或甲基-17α-丙氧基-20-酮二十二烷基丙酸酯

公开(公告)号：US3721687A

公开(公告)日：1973-03-20

申请号：US3721687D

申请日：1970-06-08

申请人： GLAXO LAB LTD

发明人： MAY P , ELKS J , PHILLIPPS G

IPC分类号： A61K31/573 , C07J5/00 , G02B7/22 , C07C169/34

CPC分类号： A61K31/573 , C07J5/00 , G02B7/22 , Y10S514/887

摘要： ANTI-INFLAMMATORY STERIODS OF THE FORMULA

9-Y,11-X,16-R3,17-(R2-O-),17-(R1-CH2-CO-)ANDROST-4-EN-

WHEREIN R1 IS A FLUORINE, CHLORINE, BROMINE OR IODINE ATOM, R2 IS AN ALKANOXY GROUP CONTAINING 1-4 CARBON ATOMS, R3 IS AN ALKYL GROUP CONTAINING 1-4 CARBON ATOMS OR A METHYLENE GROUP (=CH2), X IS A HYDROXY GROUP IN THE B-CONFIGURATION OR A KETO GROUP, Y IS A FLUORINE OR CHLORINE ATOM, AND = REPRESENTS A SINGLE OR DOUBLE BOND BETWEEN THE 1AND 2-POSITIONS OF THE MOLECULE.

3-ONE