公开(公告)号：US10245310B2

公开(公告)日：2019-04-02

申请号：US15501474

申请日：2015-08-05

Applicant: GLAXOSMITHKLINE BIOLOGICALS SA

Inventor： Francesco Berti ,  Roberta Cozzi ,  Domenico Maione ,  Cira Daniela Rinaudo ,  Immaculada Margarit Y Ros ,  Guido Grandi

IPC: A61K39/09 ,  A61K39/095 ,  A61K47/48

Abstract: The invention provides a conjugate comprising an antigen and a carrier molecule, wherein the carrier molecule comprises a BP-2a antigen and a spb1 antigen. BP-2a and spb1 are Streptococcus agalactiae antigens. The conjugate may be used in a method for raising an immune response in a mammal, the method comprising administering the conjugate to the mammal. Also provided are pharmaceutical compositions, particularly vaccines, comprising the conjugate.