公开(公告)号：US09371303B2

公开(公告)日：2016-06-21

申请号：US14593071

申请日：2015-01-09

Applicant: GREEN CROSS CORPORATION

Inventor： Soongyu Choi ,  Kwang-Seop Song ,  Suk Ho Lee ,  Min Ju Kim ,  Hee Jeong Seo ,  Eun-Jung Park ,  Younggyu Kong ,  So Ok Park ,  Hyunku Kang ,  Myung Eun Jung ,  Kinam Lee ,  Hyun Jung Kim ,  Jun Sung Lee ,  Min Woo Lee ,  Mi-Soon Kim ,  Dong Ho Hong ,  Misuk Kang

IPC: A61K31/351 ,  C07D407/04 ,  C07D309/10 ,  C07D405/10 ,  C07D407/10 ,  C07D407/14 ,  C07D409/04 ,  C07D409/10 ,  C07D411/10 ,  C07D413/04 ,  C07D405/14 ,  C07D413/10 ,  C07D409/14 ,  C07D413/12 ,  C07D413/14

CPC classification number: C07D309/10 ,  C07D405/10 ,  C07D405/14 ,  C07D407/04 ,  C07D407/10 ,  C07D407/14 ,  C07D409/04 ,  C07D409/10 ,  C07D409/14 ,  C07D411/10 ,  C07D413/04 ,  C07D413/10 ,  C07D413/12 ,  C07D413/14

Abstract: A compound with a diphenylmethane moiety having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney is disclosed. A pharmaceutical composition including the compound as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes is disclosed. A method for preparing the compound, and a method for preventing or treating metabolic disorders, particularly diabetes, by using the compound is provided.