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公开(公告)号：US20230218925A1
公开(公告)日：2023-07-13
申请号：US18179246
申请日：2023-03-06
发明人： Peter Nakaji , David Brachman , Heyoung McBride , Emad Youssef , Theresa Thomas
IPC分类号： A61N5/10
CPC分类号： A61N5/1014 , A61N5/1027 , A61N5/1007 , A61N5/103 , A61N2005/101 , A61N2005/1009 , A61N2005/1023 , A61N2005/1024
摘要： Carriers for embodying radioactive seeds, as well as a device for loading and customizing brachytherapy carriers based on the principles of optimizing a more precise and predictable dosimetry, and adaptable to the geometric challenges of a tumor bed in a real-time setting. The present disclosure relates to a specialized loading device designed to enable a medical team to create a radionuclide carrier for each patient and tumor reliably, reproducibly and efficiently.
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公开(公告)号：US20230211176A1
公开(公告)日：2023-07-06
申请号：US17936149
申请日：2022-09-28
发明人： David Brachman , John Baker , Heidi Cole , Adam Turner
CPC分类号： A61N5/1007 , G21F3/00 , A61N5/1015 , A61N2005/1024 , A61N2005/1094
摘要： The disclosure is directed to devices for use in radiation therapy. Various configurations of shielding materials within shielding layers, such as for use in shielding radiation from radioactive sources within implanted radioactive carriers, are discussed herein.
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公开(公告)号：US10888710B1
公开(公告)日：2021-01-12
申请号：US15824182
申请日：2017-11-28
发明人： David Brachman , Emad Youssef , Peter Nakaji , Evan K. Fram
IPC分类号： A61N5/10
摘要： A transparent loading apparatus (also referred to herein as a “loader”) may partially or entirely comprise transparent material that allows light to pass through the loader and provides the viewer (whether manual or automated) a view of a radioactive seed, a seed carrier, a loading needle, etc. within the loader. In some embodiments, carrier material (e.g., collagen and/or other biocompatible material) and radioactive seeds (e.g., including a metal shielding and radioactive isotope) may transmit light to different degrees. For example, certain carriers, such as collagen carriers, may be translucent, while seeds may be opaque (or mostly opaque) to light. The systems discussed herein allow a viewer to detect location of a seed within a loader, and even within a carrier, because of these different light transmissivity characteristics.
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公开(公告)号：US10350431B2
公开(公告)日：2019-07-16
申请号：US15383724
申请日：2016-12-19
发明人： Peter Nakaji , David Brachman , Heyoung McBride , Emad Youssef , Theresa Thomas
IPC分类号： A61N5/10
摘要： Carriers for embodying radioactive seeds, as well as a device for loading and customizing brachytherapy carriers based on the principles of optimizing a more precise and predictable dosimetry, and adaptable to the geometric challenges of a tumor bed in a real-time setting. The present disclosure relates to a specialized loading device designed to enable a medical team to create a radionuclide carrier for each patient and tumor reliably, reproducibly and efficiently.
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公开(公告)号：US11673002B2
公开(公告)日：2023-06-13
申请号：US17114976
申请日：2020-12-08
发明人： David Brachman , Emad Youssef , Peter Nakaji , Evan K. Fram
IPC分类号： A61N5/10
CPC分类号： A61N5/1007 , A61N2005/101 , A61N2005/1009
摘要： A transparent loading apparatus (also referred to herein as a “loader”) may partially or entirely comprise transparent material that allows light to pass through the loader and provides the viewer (whether manual or automated) a view of a radioactive seed, a seed carrier, a loading needle, etc. within the loader. In some embodiments, carrier material (e.g., collagen and/or other biocompatible material) and radioactive seeds (e.g., including a metal shielding and radioactive isotope) may transmit light to different degrees. For example, certain carriers, such as collagen carriers, may be translucent, while seeds may be opaque (or mostly opaque) to light. The systems discussed herein allow a viewer to detect location of a seed within a loader, and even within a carrier, because of these different light transmissivity characteristics.
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6.发明授权公开(公告)号：US11278736B2
公开(公告)日：2022-03-22
申请号：US16388436
申请日：2019-04-18
发明人： David Brachman , Peter Nakaji , Heyoung McBride , Emad Youssef , Theresa Thomas
IPC分类号： A61N5/10
摘要： Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors.
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公开(公告)号：US20240066318A1
公开(公告)日：2024-02-29
申请号：US18143267
申请日：2023-05-04
发明人： David Brachman , Emad Youssef , Peter Nakaji , Evan K. Fram
IPC分类号： A61N5/10
CPC分类号： A61N5/1007 , A61N2005/1009 , A61N2005/101
摘要： A transparent loading apparatus (also referred to herein as a “loader”) may partially or entirely comprise transparent material that allows light to pass through the loader and provides the viewer (whether manual or automated) a view of a radioactive seed, a seed carrier, a loading needle, etc. within the loader. In some embodiments, carrier material (e.g., collagen and/or other biocompatible material) and radioactive seeds (e.g., including a metal shielding and radioactive isotope) may transmit light to different degrees. For example, certain carriers, such as collagen carriers, may be translucent, while seeds may be opaque (or mostly opaque) to light. The systems discussed herein allow a viewer to detect location of a seed within a loader, and even within a carrier, because of these different light transmissivity characteristics.
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公开(公告)号：US20210228905A1
公开(公告)日：2021-07-29
申请号：US17114976
申请日：2020-12-08
发明人： David Brachman , Emad Youssef , Peter Nakaji , Evan K. Fram
IPC分类号： A61N5/10
摘要： A transparent loading apparatus (also referred to herein as a “loader”) may partially or entirely comprise transparent material that allows light to pass through the loader and provides the viewer (whether manual or automated) a view of a radioactive seed, a seed carrier, a loading needle, etc. within the loader. In some embodiments, carrier material (e.g., collagen and/or other biocompatible material) and radioactive seeds (e.g., including a metal shielding and radioactive isotope) may transmit light to different degrees. For example, certain carriers, such as collagen carriers, may be translucent, while seeds may be opaque (or mostly opaque) to light. The systems discussed herein allow a viewer to detect location of a seed within a loader, and even within a carrier, because of these different light transmissivity characteristics.
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9.发明授权公开(公告)号：US10265542B2
公开(公告)日：2019-04-23
申请号：US15349455
申请日：2016-11-11
发明人： David Brachman , Peter Nakaji , Heyoung McBride , Emad Youssef , Theresa Thomas
摘要： Brachytherapy radioisotope carrier systems and methodology for providing real-time customized brachytherapy treatment to subjects with tumors difficult to control using conventional radiation therapy techniques. The invention generally relates to devices, methods and kits for providing customized radionuclide treatments, to help cure, slow progression or regrowth, or ameliorate the symptoms associated with tumors.
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公开(公告)号：US10080909B2
公开(公告)日：2018-09-25
申请号：US15223806
申请日：2016-07-29
发明人： David Brachman , Evan Fram , Heyoung McBride , Peter Nakaji , Theresa Thomas , Emad Youssef
IPC分类号： A61N5/10
CPC分类号： A61N5/1007 , A61N2005/1009 , A61N2005/101 , A61N2005/1024
摘要： An apparatus and method for loading brachytherapy carriers with radioactive seeds in order to implement brachytherapy treatment protocols with more precise and predictable dosimetry. These apparatuses and methods enable a medical team to create a radionuclide carrier for each patient and tumor reliably, reproducibly and efficiently.
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