Nanostructured separation and analysis devices for biological membranes
    1.
    发明授权
    Nanostructured separation and analysis devices for biological membranes 有权
    用于生物膜的纳米结构分离和分析装置

    公开(公告)号:US06913697B2

    公开(公告)日:2005-07-05

    申请号:US10338654

    申请日:2003-01-09

    IPC分类号: B01D11/00 B01D61/14

    摘要: The present invention provides a nanostructured device comprising a substrate including nanotroughs therein; and a lipid bilayer suspended on or supported in the substrate. A separation method is also provided comprising the steps of supporting or suspending a lipid bilayer on a substrate; wherein the substrate comprises nanostructures and wherein the lipid bilayer comprises at least one membrane associated biomolecule; and applying a driving force to the lipid bilayer to separate the membrane associated biomolecule from the lipid bilayer and to drive the membrane associated biomolecule into the nanostructures.

    摘要翻译: 本发明提供一种纳米结构装置,其包括其中包括纳沟的基板; 和悬浮在或支撑在基底中的脂质双层。 还提供了一种分离方法,包括以下步骤:在基质上支持或悬浮脂质双层; 其中所述底物包含纳米结构,并且其中所述脂质双层包含至少一个膜缔合的生物分子; 并将驱动力施加到脂质双层以将膜相关生物分子与脂质双层分离并将膜相关联的生物分子驱动到纳米结构中。