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公开(公告)号：US11844952B2
公开(公告)日：2023-12-19
申请号：US17164350
申请日：2021-02-01
Applicant: Galvani Bioelectronics Limited
Inventor： Rizwan Bashirullah
CPC classification number: A61N1/3787 , A61B5/0026 , A61B5/0031 , A61N1/0556 , A61N1/3605 , A61N1/375 , A61N1/3754 , A61N1/3756 , A61N1/37223 , H04B5/0081 , A61B2560/0219 , A61M2205/3538 , A61M2205/3569 , H04B5/0075
Abstract: Implantable systems are described that include a stimulation device positionable in vivo and configured to communicatively couple to electrodes configured to stimulate or block body tissue and an auxiliary device positionable in vivo and including one or more coils configured to wirelessly couple, in vivo, to the stimulation device and to wirelessly couple to an ex vivo device. The auxiliary device may include a coil driver and a power source controlled by a processor and memory for storing data instructions for the coil driver and for storing data received from the stimulation device. The auxiliary device may also include a radio transceiver and an antenna. The stimulation device may include a housing, a coil, a power source and an integrated circuit for controlling the electrodes. The stimulation device may be coupled to a cuff via a lead and physically coupled to the auxiliary device.
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公开(公告)号：US11672972B2
公开(公告)日：2023-06-13
申请号：US15733276
申请日：2018-12-11
Applicant: Galvani Bioelectronics Limited , UCL Business PLC
Inventor： Rizwan Bashirullah , Gerald Edwin Hunsberger , Matteo Donega , Daniel Chew , David Holder , Kirill Aristovich
CPC classification number: A61N1/0556 , A61N1/36053 , A61N1/36182
Abstract: A nerve interface device including at least one cuff portion having an assembled position in which the cuff portion forms at least part of a passageway for receiving a nerve along a longitudinal axis passing through the passageway; and first and second rings of electrodes mounted on the at least one cuff portion, each ring of electrodes including a plurality of electrodes. Each electrode in the first ring has a corresponding longitudinally-aligned electrode in the second ring so as to form a plurality of pairs of electrodes spaced apart from each other along the longitudinal axis. The plurality of pairs of electrodes includes at least a first pair of electrodes, the first pair of electrodes mounted on the at least one cuff portion. The at least one cuff portion includes an asymmetric configuration about a central axis perpendicular to the longitudinal cuff axis.
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Patent Agency Ranking
3.发明申请公开(公告)号：US20230010306A1
公开(公告)日：2023-01-12
申请号：US17785374
申请日：2020-12-15
Applicant: Galvani Bioelectronics Limited
Inventor： Rizwan Bashirullah , Gerald Edwin Hunsberger
Abstract: A stent for intravascular stimulation comprises a scaffold comprising first and second scaffold structures, each scaffold structure comprising at least one substantially annular portion. The stent further comprises one or more anodal electrodes formed from or electrically coupled to at least a substantially annular portion of the first scaffold structure and one or more cathodal electrodes electrically formed from or coupled to at least a substantially annular portion of the second scaffold structure. The stent further comprises an anodal lead electrically coupled to the first scaffold structure to form a conductive path from the one or more anodal electrodes to a generator and a cathodal lead electrically coupled to the second scaffold structure to form a conductive path from the one or more cathodal electrodes to the generator. The stent further comprises a sleeve of insulating material, wherein the scaffold structures are attached to or formed on the sleeve of insulating material and are separated from each other by a distance such that the first and second scaffold structures are electrically insulated from each other.
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公开(公告)号：US20220054838A1
公开(公告)日：2022-02-24
申请号：US17415641
申请日：2019-12-13
Inventor： Michael John Carr , Rizwan Bashirullah , Kenichi Yoshida
IPC: A61N1/36
Abstract: An implantable neurostimulation system comprises at least one neural interface device for stimulating and/or inhibiting neural activity in a nerve such as the cervical vagus nerve. The device comprises first and second electrodes and at least one signal generator configured to generate first and second electrical signals that stimulate and/or inhibit neural activity in the nerve via the first and second electrodes. The first electrical signal is configured to stimulate neural activity in the nerve to cause at least one pre-determined physiological response; and the second electrical signal is configured to inhibit neural activity in the nerve to at least partially suppress the least one pre-determined physiological response.
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公开(公告)号：US20220296886A1
公开(公告)日：2022-09-22
申请号：US17619572
申请日：2020-06-17
Applicant: Galvani Bioelectronics Limited
Inventor： Rizwan Bashirullah , Gerald Edwin Hunsberger
Abstract: A neuromodulation device for measuring an evoked response comprising a first electrode; a second electrode, wherein the first and second electrodes are alternately configured as a stimulation electrode; a sensing electrode for sensing an evoked response to a stimulus pulse; and a controller configured to measure an evoked response at the sensing electrode after a stimulus pulse at a first stimulation electrode configuration and after a stimulus pulse at a second alternate stimulation electrode configuration, and to add said pair of measurements.
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公开(公告)号：US10933248B2
公开(公告)日：2021-03-02
申请号：US15803405
申请日：2017-11-03
Applicant: Galvani Bioelectronics Limited
Inventor： Rizwan Bashirullah
Abstract: Implantable systems are described that include a stimulation device positionable in vivo and configured to communicatively couple to electrodes configured to stimulate or block body tissue and an auxiliary device positionable in vivo and including one or more coils configured to wirelessly couple, in vivo, to the stimulation device and to wirelessly couple to an ex vivo device. The auxiliary device may include a coil driver and a power source controlled by a processor and memory for storing data instructions for the coil driver and for storing data received from the stimulation device. The auxiliary device may also include a radio transceiver and an antenna. The stimulation device may include a housing, a coil, a power source and an integrated circuit for controlling the electrodes. The stimulation device may be coupled to a cuff via a lead and physically coupled to the auxiliary device.
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公开(公告)号：US10576172B2
公开(公告)日：2020-03-03
申请号：US15803496
申请日：2017-11-03
Applicant: Galvani Bioelectronics Limited
Inventor： Rizwan Bashirullah
Abstract: An implantable system is disclosed that includes an encapsulated housing including a radioactive source. The encapsulated housing is internally coated with a light-generating coating that converts the radioactive energy to light, that is then output in vivo to a photodiode positioned proximate to at least part of the encapsulated housing in vivo. The photodiode is configured to generate electrical current from the light, which electrical current is output to a power conditioning circuit that is configured to use the electrical current as an input electrical current and to output power to a load in vivo. The encapsulated may also be internally coated, at least in part, with a light directing coating that causes light to be directed toward an optical lens that focuses the light on the photodiode. The radioactive source may be a gas having a low half-life and which poses no health risk to a patient if released.
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