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公开(公告)号：US20080193431A1
公开(公告)日：2008-08-14
申请号：US11383487
申请日：2006-05-15
Applicant: Gang Zheng , Jerry D. Glickson , Britton Chance , Edward James Delikatny , Klara Stefflova , Juan Chen
Inventor： Gang Zheng , Jerry D. Glickson , Britton Chance , Edward James Delikatny , Klara Stefflova , Juan Chen
CPC classification number: A61K41/0071 , A61K38/00 , A61K41/0057 , A61K41/0076 , A61K47/544 , A61K47/549 , A61K47/64 , A61K47/65 , C07K5/1008 , C07K5/101 , C07K5/1021 , C07K5/1024 , C07K7/06
Abstract: The present invention relates to the field of conjugates comprising a substrate which is attached to at least one photoactivatable killing agent and at least one first quencher, and methods for their use. More particularly, the present invention relates to photodynamic therapy agents. The invention further relates to methods for decontaminating blood and methods for treating cancer or viral infection in a subject using the conjugates of the present invention.
Abstract translation: 本发明涉及包含与至少一种可光活化杀伤剂和至少一种第一猝灭剂连接的底物的缀合物领域及其使用方法。 更具体地说，本发明涉及光动力治疗剂。 本发明还涉及使用本发明的缀合物来净化血液的方法和用于治疗受试者的癌症或病毒感染的方法。
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公开(公告)号：US08133482B2
公开(公告)日：2012-03-13
申请号：US11383487
申请日：2006-05-15
Applicant: Gang Zheng , Jerry P. Glickson , Britton Chance , Edward James Delikatny , Klara Stefflova , Juan Chen
Inventor： Gang Zheng , Jerry P. Glickson , Britton Chance , Edward James Delikatny , Klara Stefflova , Juan Chen
CPC classification number: A61K41/0071 , A61K38/00 , A61K41/0057 , A61K41/0076 , A61K47/544 , A61K47/549 , A61K47/64 , A61K47/65 , C07K5/1008 , C07K5/101 , C07K5/1021 , C07K5/1024 , C07K7/06
Abstract: The present invention relates to the field of conjugates comprising a substrate which is attached to at least one photoactivatable killing agent and at least one first quencher, and methods for their use. More particularly, the present invention relates to photodynamic therapy agents. The invention further relates to methods for decontaminating blood and methods for treating cancer or viral infection in a subject using the conjugates of the present invention.
Abstract translation: 本发明涉及包含与至少一种可光活化杀伤剂和至少一种第一猝灭剂连接的底物的缀合物领域及其使用方法。 更具体地说，本发明涉及光动力治疗剂。 本发明还涉及使用本发明的缀合物来净化血液的方法和用于治疗受试者的癌症或病毒感染的方法。
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公开(公告)号：US20100075899A1
公开(公告)日：2010-03-25
申请号：US12443019
申请日：2007-09-28
Applicant: Gang Zheng , Klara Stefflova
Inventor： Gang Zheng , Klara Stefflova
IPC: A61K38/16 , C07K5/113 , C07K5/10 , C07K7/06 , C07K7/08 , C07K14/00 , C12N5/09 , A61K38/07 , A61K38/08 , A61K38/10 , A61P35/00
CPC classification number: C07K5/1021 , A61K38/00 , A61K41/0057 , A61K41/0066 , A61K41/0071 , A61K47/64 , A61K47/65 , A61K49/0036 , A61K49/0052 , A61K49/0056 , C07K5/101 , C07K5/1016 , C07K7/06
Abstract: The present invention relates to the field of conjugates comprising a substrate, a photosensitizer, and a targeting ligand, and methods for their use. More particularly, the invention further relates to methods for treating cancer in a subject using the conjugates of the present invention.
Abstract translation: 本发明涉及包含底物，光敏剂和靶向配体的缀合物领域及其使用方法。 更具体地，本发明还涉及使用本发明的缀合物治疗受试者的癌症的方法。
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