Compositions and methods for inhibiting cell senescence and hyperproliferative disorders
    1.
    发明申请
    Compositions and methods for inhibiting cell senescence and hyperproliferative disorders 审中-公开
    用于抑制细胞衰老和过度增殖性疾病的组合物和方法

    公开(公告)号:US20060160732A1

    公开(公告)日:2006-07-20

    申请号:US10961824

    申请日:2004-10-08

    申请人: Gary Aronson

    发明人: Gary Aronson

    摘要: The present disclosure provides compositions and methods for inhibiting cell and/or organismic senescence by treating conditions associated with aging and preventing undesirable cell proliferation. Compositions provided in the present disclosure include a transport agent attached to a therapeutic agent portion, wherein the transport agent portion has a role in transporting the composition across one or more biological membranes and the therapeutic agent portion prolongs cell life by effects on the proliferative capacity of a cell. In particular, the therapeutic agent includes a first region having telomerase activity and a second region having tumor suppressor activity.

    摘要翻译: 本公开提供通过治疗与衰老相关的病症并预防不期望的细胞增殖来抑制细胞和/或生物衰老的组合物和方法。 在本公开中提供的组合物包括连接到治疗剂部分的运输剂,其中所述运输剂部分具有通过一种或多种生物膜运输所述组合物的作用,并且所述治疗剂部分通过对增殖能力的影响延长细胞寿命 一个单元格 特别地,治疗剂包括具有端粒酶活性的第一区域和具有肿瘤抑制活性的第二区域。