摘要:
The present disclosure provides compositions and methods for inhibiting cell and/or organismic senescence by treating conditions associated with aging and preventing undesirable cell proliferation. Compositions provided in the present disclosure include a transport agent attached to a therapeutic agent portion, wherein the transport agent portion has a role in transporting the composition across one or more biological membranes and the therapeutic agent portion prolongs cell life by effects on the proliferative capacity of a cell. In particular, the therapeutic agent includes a first region having telomerase activity and a second region having tumor suppressor activity.