Systems and methods for multi-spectral bioluminescence tomography
    1.
    发明授权
    Systems and methods for multi-spectral bioluminescence tomography 有权
    多光谱生物发光断层扫描的系统和方法

    公开(公告)号:US08676302B2

    公开(公告)日:2014-03-18

    申请号:US11619495

    申请日:2007-01-03

    IPC分类号: A61B6/00

    摘要: Bioluminescent imaging has proven to be a valuable tool for monitoring physiological and pathological activities at cellular and molecular levels in living small animals. Using biological techniques, target cells can be tagged with reporters which generate characteristic photons in a wide spectrum covering the infra-red range. Part of the diffused light can reach the body surface of a subject/specimen (e.g., a small animal), be separated into several spectral bands using optical means, and collected by a sensitive camera. Systems and methods are disclosed herein for multi-spectral bioluminescence tomography (MBLT), in which an image of an underlying 3D bioluminescent source distribution is synergistically reconstructed from spectrally resolved datasets externally measured. This MBLT process involves two or multiple imaging modalities that produce structural information of the object and optical properties of the object as well to enable and improve the quality of MBLT.

    摘要翻译: 已经证明生物发光成像是监测活的小动物细胞和分子水平的生理和病理活动的有价值的工具。 使用生物学技术,靶细胞可以用记录器进行标记,记者在覆盖红外范围的广谱中产生特征光子。 扩散光的一部分可以到达对象/标本(例如,小动物)的身体表面,使用光学装置分离成若干光谱带,并由敏感摄像机收集。 本文公开了用于多光谱生物发光断层摄影(MBLT)的系统和方法,其中底层3D生物发光源分布的图像从外部测量的光谱解析数据集协同地重建。 该MBLT过程涉及产生物体的结构信息和对象的光学性质的两个或多个成像模态,以及实现和提高MBLT的质量。

    SYSTEMS AND METHODS FOR MULTI-SPECTRAL BIOLUMINESCENCE TOMOGRAPHY
    2.
    发明申请
    SYSTEMS AND METHODS FOR MULTI-SPECTRAL BIOLUMINESCENCE TOMOGRAPHY 有权
    多光谱生物荧光光谱的系统与方法

    公开(公告)号:US20070244395A1

    公开(公告)日:2007-10-18

    申请号:US11619495

    申请日:2007-01-03

    IPC分类号: A61B5/00

    摘要: Bioluminescent imaging has proven to be a valuable tool for monitoring physiological and pathological activities at cellular and molecular levels in living small animals. Using biological techniques, target cells can be tagged with reporters which generate characteristic photons in a wide spectrum covering the infra-red range. Part of the diffused light can reach the body surface of a subject/specimen (e.g., a small animal), be separated into several spectral bands using optical means, and collected by a sensitive camera. Systems and methods are disclosed herein for multi-spectral bioluminescence tomography (MBLT), in which an image of an underlying 3D bioluminescent source distribution is synergistically reconstructed from spectrally resolved datasets externally measured. This MBLT process involves two or multiple imaging modalities that produce structural information of the object and optical properties of the object as well to enable and improve the quality of MBLT.

    摘要翻译: 已经证明生物发光成像是监测活的小动物细胞和分子水平的生理和病理活动的有价值的工具。 使用生物学技术,靶细胞可以用记录器进行标记,记者在覆盖红外范围的广谱中产生特征光子。 扩散光的一部分可以到达对象/标本(例如,小动物)的身体表面,使用光学装置分离成若干光谱带,并由敏感摄像机收集。 本文公开了用于多光谱生物发光断层摄影(MBLT)的系统和方法,其中底层3D生物发光源分布的图像从外部测量的光谱解析数据集协同地重建。 该MBLT过程涉及产生物体的结构信息和对象的光学性质的两个或多个成像模态,以及实现和提高MBLT的质量。

    Computational optical biopsy
    3.
    发明申请
    Computational optical biopsy 审中-公开
    计算光学活检

    公开(公告)号:US20070093700A1

    公开(公告)日:2007-04-26

    申请号:US11444282

    申请日:2006-05-31

    IPC分类号: A61B5/00

    CPC分类号: A61B5/0059

    摘要: Methods, systems and apparatuses for reconstructing a light source distribution or estimating a light source feature within a subject include an optical data receiving mechanism that is positionable at least at one location within the subject and is configured to acquire signal data from a light source located within a subject. A computational device is configured to receive signal data acquired by the optical data receiving mechanism and to reconstruct the light source distribution or to estimate a light source feature from at least a portion of the received data.

    摘要翻译: 用于重建光源分布或估计对象内的光源特征的方法,系统和装置包括光学数据接收机构,该光学数据接收机构至少可位于对象内的一个位置,并被配置为从位于所述对象内的光源获取信号数据 课程。 计算设备被配置为接收由光学数据接收机构获取的信号数据,并重建光源分布或者从至少一部分接收到的数据估计光源特征。

    Methods for improved single photon emission computed tomography using exact and stable region of interest reconstructions
    4.
    发明授权
    Methods for improved single photon emission computed tomography using exact and stable region of interest reconstructions 有权
    使用精确和稳定的兴趣重建区域改进单光子发射计算机断层摄影的方法

    公开(公告)号:US08952333B2

    公开(公告)日:2015-02-10

    申请号:US12938303

    申请日:2010-11-02

    IPC分类号: G06T11/00 A61B6/03

    摘要: The present invention provides systems, methods, and devices for improved computed tomography (CT) and, more specifically, to methods for improved single photon computed tomography (SPECT) using exact and stable region of interest (ROI) reconstructions. This technology can be extended across all tomographic modalities. Embodiments provide a method and a system for reconstructing an image from projection data provided by a single photon emission computed tomography scanner comprising: identifying a region of interest in an object; defining an attenuation coefficient and object boundary; computing the generalized Hilbert transform of the data through the defined region of interest and a known subregion; and reconstructing the image with improved temporal resolution at lower radiation doses, wherein the reconstructing comprises performing a reconstruction method that yields an exact and stable reconstruction. Embodiments also provide a method and a system for reconstructing an image from projection data provided by a single photon emission computed tomography scanner comprising: identifying a region of interest in an object; defining an attenuation coefficient and object boundary; and reconstructing the images by minimizing the high order total variation while minimizing the data discrepancy.

    摘要翻译: 本发明提供用于改进计算机断层摄影(CT)的系统,方法和装置,更具体地,涉及使用精确和稳定的感兴趣区域(ROI)重建的改进的单光子计算机断层摄影(SPECT)的方法。 该技术可以跨越所有断层摄影模式进行扩展。 实施例提供了一种用于从由单个光子发射计算机断层摄影扫描仪提供的投影数据重建图像的方法和系统,包括:识别对象中的感兴趣区域; 定义衰减系数和物体边界; 通过所定义的感兴趣区域和已知子区域计算数据的广义希尔伯特变换; 以及在较低辐射剂量下以改进的时间分辨率重建图像,其中所述重建包括执行产生精确和稳定重建的重建方法。 实施例还提供了一种用于从由单个光子发射计算机断层摄影扫描仪提供的投影数据重建图像的方法和系统,包括:识别对象中的感兴趣区域; 定义衰减系数和物体边界; 并通过最小化高阶总变化同时最小化数据差异来重构图像。

    Mobile advertisement systems and mobile advertisement platforms using the same

    公开(公告)号:US11321739B2

    公开(公告)日:2022-05-03

    申请号:US17174361

    申请日:2021-02-12

    IPC分类号: G06Q30/00 G06Q30/02 G06V20/56

    摘要: A mobile advertisement system mounted on a back window of a vehicle using suction cups is presented according to aspects of present disclosure. In certain embodiments, the mobile advertisement system connects wirelessly to a mobile advertisement server, sends its GPS location updates periodically to mobile advertisement server, receives advertisements and delivery instructions from mobile advertisement server in response to the GPS location updates sent, displays advertisements on the display screen of the mobile advertisement system according to the corresponding delivery instructions when at least one automobile is detected, and transmits delivery confirmations to mobile advertisement server after each advertisement is displayed according to the corresponding delivery instructions. A video camera detects whether there are any automobile behind, and mobile advertisement system will not display advertisements when there is no automobile behind. brightness of advertisement display is in directly proportional to light intensity outside detected by a light sensor.

    Mobile advertisement systems and methods of using the same

    公开(公告)号:US10929887B2

    公开(公告)日:2021-02-23

    申请号:US15657196

    申请日:2017-07-23

    IPC分类号: G06Q30/02 H04W4/02 H04W4/21

    摘要: The present disclosure relates to a mobile advertisement system and a method of advertisement using the mobile advertisement system. In certain embodiments, mobile advertisement system includes: a mobile advertisement server and one or more mobile advertisement delivery systems. The mobile advertisement server registers many advertisers and subscribers, receives various advertisements and their corresponding delivery instructions from advertisers, and dispatch advertisements and delivery instructions to the subscribers. Each of mobile advertisement delivery systems corresponds to one of registered subscribers, and is connected to mobile advertisement server. Each mobile advertisement delivery systems receive advertisements and delivery instructions from mobile advertisement server, and displays advertisements on respective mobile advertisement display device according to corresponding delivery instructions. Each delivery instruction corresponds to an advertisement, and includes: delivery time and delivery location. Each mobile advertisement delivery systems displays advertisements when it is positioned in a region specified by delivery location and during delivery time.

    Method of forming a straight top main pole for PMR bevel writer
    7.
    发明授权
    Method of forming a straight top main pole for PMR bevel writer 有权
    形成用于PMR斜面写入器的直顶主极的方法

    公开(公告)号:US08893376B1

    公开(公告)日:2014-11-25

    申请号:US13568685

    申请日:2012-08-07

    IPC分类号: G11B5/127 H04R31/00

    CPC分类号: G11B5/3163 G11B5/3116

    摘要: A method of forming a magnetic recording head is provided. The method comprises the steps of forming a damascene trench comprising a lower region having a substantially trapezoidal cross-section and an upper region having a substantially rectangular cross-section, and providing a magnetic material within the damascene trench.

    摘要翻译: 提供一种形成磁记录头的方法。 该方法包括以下步骤:形成镶嵌沟槽,其包括具有基本上梯形横截面的下部区域和具有基本上矩形横截面的上部区域,以及在镶嵌槽内提供磁性材料。

    APPARATUS AND METHOD FOR AUTOMATIC WHITE BALANCE WITH SUPPLEMENTARY SENSORS
    8.
    发明申请
    APPARATUS AND METHOD FOR AUTOMATIC WHITE BALANCE WITH SUPPLEMENTARY SENSORS 有权
    具有补充传感器的自动白平衡的装置和方法

    公开(公告)号:US20130083216A1

    公开(公告)日:2013-04-04

    申请号:US13252457

    申请日:2011-10-04

    IPC分类号: H04N9/73

    CPC分类号: H04N9/735

    摘要: An apparatus and method for An image capture device for Automatic White Balance (AWB) are provided. The device includes a camera for capturing an image, a primary sensor for sensing environmental conditions of the image capture device and for generating data regarding the environmental conditions, a plurality of supplementary sensors for sensing the environmental conditions of the image capture device and for generating supplementary data regarding the environmental conditions, an AWB unit for performing an AWB operation on the captured image according to the generated data and the generated supplementary data, and a controller for controlling the camera, the primary sensor, the plurality of supplementary sensors and the AWB unit.

    摘要翻译: 提供了一种用于自动白平衡(AWB)的图像捕获装置的装置和方法。 该装置包括用于捕获图像的相机,用于感测图像捕获装置的环境条件并用于生成关于环境条件的数据的主传感器,用于感测图像捕获装置的环境条件并用于产生补充的多个辅助传感器 关于环境条件的数据,用于根据所生成的数据和所生成的补充数据对捕获的图像执行AWB操作的AWB单元,以及用于控制相机,主传感器,多个辅助传感器和AWB单元的控制器 。

    Perpendicular magnetic recording writer main pole having imbedded non-magnetic core and de-coupled pole tip
    9.
    发明授权
    Perpendicular magnetic recording writer main pole having imbedded non-magnetic core and de-coupled pole tip 有权
    垂直磁记录器主极嵌有非磁芯和脱耦极头

    公开(公告)号:US08179634B2

    公开(公告)日:2012-05-15

    申请号:US12005786

    申请日:2007-12-27

    IPC分类号: G11B5/127

    摘要: Methods and structures for the fabrication of a thin film, perpendicular recording write head are disclosed. The structure provides a pole tip separated from a rear pole by a non-magnetic separation layer located adjacent the flare point. The rear pole contains an imbedded non-magnetic layer. The separated pole tip and imbedded layer aid in the high data rate recording as well as the erasure performance of the write pole structure. The fabrication involves the deposition of two different oxide layers which have mutually high etch selectivities. This characteristic allows a write pole structure to be built wherein the track width is independent of the location of the flare point. The process also produces a structure wherein the placement of the throat height of the shield is self aligned to the flare point of the write pole.

    摘要翻译: 公开了用于制造薄膜垂直记录写头的方法和结构。 该结构提供了通过位于火炬点附近的非磁性分离层与后极分离的极尖。 后极包含嵌入的非磁性层。 分离的极尖和嵌入层有助于高数据速率记录以及写柱结构的擦除性能。 该制造涉及沉积具有相互高蚀刻选择性的两个不同的氧化物层。 该特征允许构建写极结构,其中轨道宽度独立于耀斑点的位置。 该过程还产生一种结构,其中屏蔽件的喉部高度的放置与写入极的扩张点自对准。

    Magnetic head for perpendicular recording having stepped wrap around shield with independent control of write pole track width and flare point dimensions
    10.
    发明授权
    Magnetic head for perpendicular recording having stepped wrap around shield with independent control of write pole track width and flare point dimensions 有权
    用于垂直记录的磁头,具有围绕屏蔽的台阶缠绕,独立控制写入磁极宽度和扩展点尺寸

    公开(公告)号:US08049989B2

    公开(公告)日:2011-11-01

    申请号:US12005557

    申请日:2007-12-26

    IPC分类号: G11B5/147

    摘要: Methods and structures for the fabrication of a thin film, perpendicular recording write head are disclosed. The fabrication involves the deposition of two different oxide layers which have mutually high etch selectivities. This characteristic allows a write pole structure to be built wherein the track width is independent of the location of the flare point. The process also produces a structure wherein the throat height of the shield is self aligned to the location of the flare point of the write pole.

    摘要翻译: 公开了用于制造薄膜垂直记录写头的方法和结构。 该制造涉及沉积具有相互高蚀刻选择性的两个不同的氧化物层。 该特征允许构建写极结构,其中轨道宽度独立于耀斑点的位置。 该过程还产生一种结构,其中屏蔽件的喉部高度自动对准写入磁极的扩张点的位置。