公开(公告)号：US10023914B2

公开(公告)日：2018-07-17

申请号：US14886463

申请日：2015-10-19

申请人： Gendiag.exe, S.L.

发明人： Eduardo Salas ,  José Manuel Soria ,  Miroslava Ogorelkova ,  Roberto Elosua ,  Joan S. Vila ,  Sergio Castillo

IPC分类号： C07H21/04 ,  C12Q1/68 ,  C12Q1/6883 ,  C12Q1/6827 ,  C12Q1/6837

摘要： The invention relates to a method for a more appropriate thromboembolic event risk assessment based on the presence of different genetic variant. The invention also relates to a method for determining the risk of suffering a thromboembolism disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with conventional risk factors for thromboembolism as well as computer-implemented means for carrying out said method.

公开(公告)号：US20160102355A1

公开(公告)日：2016-04-14

申请号：US14886463

申请日：2015-10-19

申请人： Gendiag.exe, S.L.

发明人： Eduardo Salas ,  José Manuel Soria ,  Miroslava Ogorelkova ,  Roberto Elosua Llanos ,  Joan Vila ,  Sergio Castillo Fernandez

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q1/6827 ,  C12Q1/6837 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/156 ,  C12Q2565/501 ,  C12Q2565/102 ,  C12Q2545/113 ,  C12Q2537/113 ,  C12Q2521/319 ,  C12Q2521/307

摘要： The invention relates to a method for a more appropriate thromboembolic event risk assessment based on the presence of different genetic variant. The invention also relates to a method for determining the risk of suffering a thromboembolism disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with conventional risk factors for thromboembolism as well as computer-implemented means for carrying out said method.

摘要翻译： 本发明涉及一种基于不同遗传变体存在的更合适的血栓栓塞事件风险评估方法。 本发明还涉及通过将来自受试者的样品中的一种或多种多态性标记物的不存在或存在与血栓栓塞的常规危险因素结合来确定患有血栓栓塞性疾病的风险的方法以及用于进行血栓栓塞的计算机实施的手段 说的方法。

公开(公告)号：US10557170B2

公开(公告)日：2020-02-11

申请号：US15651017

申请日：2017-07-17

申请人： Gendiag.exe, S.L.

发明人： Eduardo Salas ,  José Manuel Soria ,  Miroslava Ogorelkova ,  Roberto Elosua Llanos ,  Joan Vila ,  Sergio Castillo Fernandez

IPC分类号： C12Q1/68 ,  C07H21/04 ,  C12Q1/6883 ,  C12Q1/6837 ,  C12Q1/6827

摘要： The invention relates to a method for a more appropriate thromboembolic event risk assessment based on the presence of different genetic variant. The invention also relates to a method for determining the risk of suffering a thromboembolism disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with conventional risk factors for thromboembolism as well as computer-implemented means for carrying out said method.

公开(公告)号：US20180066313A1

公开(公告)日：2018-03-08

申请号：US15651017

申请日：2017-07-17

申请人： Gendiag.exe, S.L.

发明人： Eduardo Salas ,  José Manuel Soria ,  Miroslava Ogorelkova ,  Roberto Elosua Llanos ,  Joan Vila ,  Sergio Castillo Fernandez

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q1/6827 ,  C12Q1/6837 ,  C12Q2521/307 ,  C12Q2521/319 ,  C12Q2537/113 ,  C12Q2565/102 ,  C12Q2565/501 ,  C12Q2600/106 ,  C12Q2600/112 ,  C12Q2600/118 ,  C12Q2600/156

摘要： The invention relates to a method for a more appropriate thromboembolic event risk assessment based on the presence of different genetic variant. The invention also relates to a method for determining the risk of suffering a thromboembolism disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with conventional risk factors for thromboembolism as well as computer-implemented means for carrying out said method.

公开(公告)号：US20160215341A1

公开(公告)日：2016-07-28

申请号：US14914742

申请日：2014-08-29

申请人： GENDIAG.EXE, S.L.

发明人： Eduardo Salas ,  Sara Pich ,  Manuel Arias ,  Roberto Elosua ,  Sergio Castillo

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/118 ,  C12Q2600/156 ,  C12Q2600/172

摘要： The invention relates to a method for determining the risk of a subject suffering from chronic kidney disease of suffering a cardiovascular disease based on the presence of different polymorphisms as well as to kits for practicing the above method. The invention also relates to a method for determining the risk of suffering a cardiovascular disease by combining the absence or presence of one or more polymorphic markers in a sample from the subject with clinical/biochemical risk factors for CVD as well as computer-implemented means for carrying out said method.

摘要翻译： 本发明涉及一种基于不同多态性的存在确定患有心血管疾病的慢性肾脏病患者的风险的方法以及用于实施上述方法的试剂盒。 本发明还涉及通过将来自受试者的样品中的一种或多种多态性标记物的不存在或存在与CVD的临床/生物化学危险因素以及计算机实施的手段相结合来确定患有心血管疾病的风险的方法 执行所述方法。