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公开(公告)号:US20170158769A1
公开(公告)日:2017-06-08
申请号:US15266105
申请日:2016-09-15
Applicant: Genentech, Inc.
Inventor: Avi ASHKENAZI , Jing QING , Christian WIESMANN , Yan WU
IPC: C07K16/28 , C07K16/30 , A61K39/395
CPC classification number: C07K16/2863 , A61K39/395 , A61K39/3955 , A61K39/39558 , A61K2039/505 , C07K16/3038 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30
Abstract: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
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公开(公告)号:US20160250287A1
公开(公告)日:2016-09-01
申请号:US15029960
申请日:2014-03-06
Applicant: GENENTECH, INC.
Inventor: Robert L. YAUCH , Xiaofen YE , Avi ASHKENAZI
IPC: A61K38/17 , A61K45/06 , A61K31/5377 , A61K31/519 , A61K31/517
CPC classification number: A61K38/179 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K45/06 , A61K2300/00
Abstract: Provided herein are combination therapies for the treatment of pathological conditions, such as cancer, using an antagonist of FGFR signaling.
Abstract translation: 本文提供了使用FGFR信号传导的拮抗剂治疗病理状况如癌症的组合疗法。
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3.
公开(公告)号:US20160244525A1
公开(公告)日:2016-08-25
申请号:US14934059
申请日:2015-11-05
Applicant: GENENTECH, INC.
Inventor: Yiyuan YIN , Avi ASHKENAZI , Paul J. CARTER , Mark CHEN , Junichiro SONODA
CPC classification number: C07K16/2863 , A61K2039/505 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3069 , C07K16/40 , C07K2317/21 , C07K2317/31 , C07K2317/34 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C12P21/02
Abstract: The invention provides dual specific anti-FGFR2 and FGFR3 (FGFR2/3) antibodies, and compositions comprising and methods of using these antibodies.
Abstract translation: 本发明提供双重特异性抗FGFR2和FGFR3(FGFR2 / 3)抗体,以及包含使用这些抗体的组合物。
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公开(公告)号:US20190330355A1
公开(公告)日:2019-10-31
申请号:US16380865
申请日:2019-04-10
Applicant: GENENTECH, INC.
Inventor: Avi ASHKENAZI , Jing QING , Christian WIESMANN , Yan WU
IPC: C07K16/28 , A61K39/395 , C07K16/30
Abstract: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
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公开(公告)号:US20170204188A1
公开(公告)日:2017-07-20
申请号:US15356483
申请日:2016-11-18
Applicant: GENENTECH, INC.
Inventor: Avi ASHKENAZI , Jing QING , Christian WIESMANN , Yan WU
CPC classification number: C07K16/2863 , A61K39/395 , A61K39/3955 , A61K39/39558 , A61K2039/505 , C07K16/3038 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30
Abstract: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
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公开(公告)号:US20160168250A1
公开(公告)日:2016-06-16
申请号:US14887042
申请日:2015-10-19
Applicant: GENENTECH, INC.
Inventor: Avi ASHKENAZI , Jing QING , Christian WIESMANN , Yan WU
IPC: C07K16/28
CPC classification number: C07K16/2863 , A61K39/395 , A61K39/3955 , A61K39/39558 , A61K2039/505 , C07K16/3038 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30
Abstract: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
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