公开(公告)号：US09625462B2

公开(公告)日：2017-04-18

申请号：US14814139

申请日：2015-07-30

Applicant: Genentech, Inc.

Inventor： Yu-Ju G. Meng ,  Kyu H. Hong ,  Johnny Gutierrez

IPC: A61K39/00 ,  C07K16/00 ,  G01N33/574 ,  C07K16/22 ,  G01N33/74

CPC classification number: G01N33/57496 ,  C07K16/22 ,  G01N33/74 ,  G01N2333/475

Abstract: The vascular endothelial growth factor (VEGF) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions, and other pathologies. Antibody-sandwich ELISA methods and kits for VEGF as an antigen are provided to detect types of VEGF levels in biological samples from animal models and human patients and can be used as a diagnostic/prognostic index.