公开(公告)号：US20180282398A1

公开(公告)日：2018-10-04

申请号：US15761887

申请日：2016-09-21

Applicant: Genentech, Inc.

Inventor： Benjamin HALEY ,  Zhilan HU ,  John C. JOLY ,  Amy Y. SHEN ,  Bradley Richard SNEDECOR

IPC: C07K16/00 ,  C12N15/113

Abstract: The present invention provides compositions comprising a Fc-containing protein wherein substantially all the Fc domains have a C-terminal lysine. Further provided are host cell for producing said compositions, methods of making said host cells and compositions, and method of use thereof.

公开(公告)号：US20230159625A1

公开(公告)日：2023-05-25

申请号：US18156215

申请日：2023-01-18

Applicant: Genentech, Inc.

Inventor： Benjamin HALEY ,  Zhilan HU ,  John C. JOLY ,  Amy Y. SHEN ,  Bradley Richard SNEDECOR

IPC: C07K16/00 ,  C12N15/113 ,  C12N15/85 ,  C12P21/02

CPC classification number: C07K16/00 ,  C12N15/1137 ,  C12N15/85 ,  C12P21/02 ,  C07K2317/14 ,  C07K2317/52 ,  C12N2310/14 ,  C12N2510/02 ,  C12N2510/00 ,  C12N2511/00 ,  C12N2310/20 ,  C07K2319/30

Abstract: The present invention provides compositions comprising a Fc-containing protein wherein substantially all the Fc domains have a C-terminal lysine. Further provided are host cell for producing said compositions, methods of making said host cells and compositions, and method of use thereof.