公开(公告)号：US10017523B2

公开(公告)日：2018-07-10

申请号：US15312482

申请日：2015-05-22

申请人： Genzyme Corporation

发明人： Paul Mason ,  Kara Carter ,  Alexandra Joseph ,  Yiding Hu ,  Jill Gregory ,  Zhong Zhao ,  Christopher Yee ,  Mohamud Mohamud ,  Yibin Xiang ,  Sanjay Danthi ,  Yinyin Huang ,  Andrew Papoulis

IPC分类号： C07D498/10 ,  C07D491/107 ,  C07D491/20 ,  C12N5/0781 ,  G01N33/50 ,  G01N33/60

CPC分类号： C07D498/10 ,  C07D491/107 ,  C07D491/20 ,  C12N5/0635 ,  G01N33/5008 ,  G01N33/60

摘要： The invention features compounds of Formula (I), Formula (I)-A and Formula (I)-B as disclosed herein, as well as methods of synthesis, therapy, diagnostics, and assays.

公开(公告)号：US20170107231A1

公开(公告)日：2017-04-20

申请号：US15312482

申请日：2015-05-22

申请人： Genzyme Corporation

发明人： Paul Mason ,  Kara Carter ,  Alexandra Joseph ,  Yiding Hu ,  Jill Gregory ,  Zhong Zhao ,  Christopher Yee ,  Mohamud Mohamud ,  Yibin Xiang ,  Sanjay Danthi ,  Yinyin Huang ,  Andrew Papoulis

IPC分类号： C07D498/10 ,  G01N33/50 ,  C12N5/0781 ,  C07D491/107 ,  G01N33/60

CPC分类号： C07D498/10 ,  C07D491/107 ,  C07D491/20 ,  C12N5/0635 ,  G01N33/5008 ,  G01N33/60

摘要： The invention features compounds of Formula (I), Formula (I)-A and Formula (I)-B as disclosed herein, as well as methods of synthesis, therapy, diagnostics, and assays.

公开(公告)号：US20180312525A1

公开(公告)日：2018-11-01

申请号：US16026901

申请日：2018-07-03

申请人： Genzyme Corporation

发明人： Paul Mason ,  Kara Carter ,  Alexandra Joseph ,  Yiding Hu ,  Jill Gregory ,  Zhong Zhao ,  Christopher Yee ,  Mohamud Mohamud ,  Yibin Xiang ,  Sanjay Danthi ,  Yinyin Huang ,  Andrew Papoulis

IPC分类号： C07D498/10 ,  G01N33/60 ,  G01N33/50 ,  C07D491/107 ,  C07D491/20 ,  C12N5/0781

CPC分类号： C07D498/10 ,  C07D491/107 ,  C07D491/20 ,  C12N5/0635 ,  G01N33/5008 ,  G01N33/60

摘要： The invention features compounds of Formula (I), Formula (I)-A and Formula (I)-B as disclosed herein, as well as methods of synthesis, therapy, diagnostics, and assays.