-
公开(公告)号：US07627665B2
公开(公告)日：2009-12-01
申请号：US09825506
申请日：2001-04-03
IPC分类号： G06F15/173
CPC分类号： H04L41/22 , H04L29/06 , H04L41/0893 , H04L41/18 , H04L43/00 , H04L43/10 , H04L63/0227 , H04L63/0263 , H04L63/10 , H04L63/1408 , H04L63/1416 , H04L67/02 , H04L67/025 , H04L67/08 , H04L67/34 , H04L67/36 , H04L69/329
摘要： A system and method for implementing an integrated information system are provided. A premises server is in communication with a variety of information sources that produce monitoring data for a premises. The premises server collects, presents, and transmits the monitoring device data to a central server capable of processing data from multiple premises servers. The central server receives the data and traverses one or more logical rule sets to determine whether the inputted data violates the rules. Based on an evaluation of the rules, the central server generates outputs in the form of communication to one or more authorized users via a variety of communication mediums and devices and/or the instigation of a variety of acts corresponding to the evaluation of the rules.
-
公开(公告)号：US08563009B2
公开(公告)日：2013-10-22
申请号：US12666102
申请日：2008-06-26
IPC分类号： A61K31/726
CPC分类号： A61K39/39 , A61K2039/55511 , A61K2039/55594 , Y02A50/412
摘要： Here we identify MMG and its alpha- and ketomycolic acid derivatives as highly bioactive lipids derived from M. bovis BCG (Copenhagen) capable of stimulating and activating human DC's at exceedingly low doses. In addition to their direct role as immunostimulators of human DC's we demonstrate their use in the development of a new generation of adjuvants suitable for human administration. We furthermore identify a number of highly active synthetic MMG analogues with great potential in cancer treatment, and for vaccine adjuvants against both infectious disease and disorders like Alzheimers disease.
摘要翻译： 在这里，我们将MMG及其α-和酮环酸衍生物鉴定为能够以极低剂量刺激和激活人类DC的牛分枝杆菌BCG（哥本哈根）的高度生物活性脂质。 除了它们作为人类DC的免疫刺激剂的直接作用之外，我们还展示了其在开发适合人类给药的新一代佐剂中的用途。 此外，我们还确定了一些在癌症治疗中具有巨大潜力的高活性合成MMG类似物，以及针对传染病和类似阿尔茨海默病的疾病的疫苗佐剂。
-
公开(公告)号：US20100310585A1
公开(公告)日：2010-12-09
申请号：US12666102
申请日：2008-06-26
IPC分类号： A61K39/00 , A61K39/395 , A61K39/40 , A61K39/118 , A61K39/015 , A61P35/00 , A61P11/06 , A61P31/00 , A61P27/14
CPC分类号： A61K39/39 , A61K2039/55511 , A61K2039/55594 , Y02A50/412
摘要： Here we identify MMG and its alpha- and ketomycolic acid derivatives as highly bioactive lipids derived from M. bovis BCG (Copenhagen) capable of stimulating and activating human DC's at exceedingly low doses. In addition to their direct role as immunostimulators of human DC's we demonstrate their use in the development of a new generation of adjuvants suitable for human administration. We furthermore identify a number of highly active synthetic MMG analogues with great potential in cancer treatment, and for vaccine adjuvants against both infectious disease and disorders like Alzheimers disease.
摘要翻译： 在这里，我们将MMG及其α-和酮环酸衍生物鉴定为能够以极低剂量刺激和激活人类DC的牛分枝杆菌BCG（哥本哈根）的高度生物活性脂质。 除了它们作为人类DC的免疫刺激剂的直接作用之外，我们还展示了其在开发适合人类给药的新一代佐剂中的用途。 此外，我们还确定了一些在癌症治疗中具有巨大潜力的高活性合成MMG类似物，以及针对传染病和类似阿尔茨海默病的疾病的疫苗佐剂。
-
-
搜索结果
3 条记录 (耗时 0.024 秒)
