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公开(公告)号：US5869084A
公开(公告)日：1999-02-09
申请号：US474071
申请日：1995-06-07
CPC分类号： A61K33/30 , A23L33/15 , A23L33/16 , A23V2002/00 , Y10S514/905
摘要： Multi-vitamin and mineral supplements for administration to lactating, non-lactating, and menopausal women, which comprise specific regimens of critical nutritional agents. The supplements are specifically tailored to meet nutritional requirements and maintain a woman's health during each stage of life.
摘要翻译： 用于哺乳期，非哺乳期和绝经期妇女的多种维生素和矿物质补充剂，其包括关键营养剂的特定方案。 补品是专门为满足营养需求量身定制，并在生命的每个阶段保持女性的健康。
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公开(公告)号：US06488956B1
公开(公告)日：2002-12-03
申请号：US09448744
申请日：1999-11-24
IPC分类号： A61K4700
CPC分类号： A61K33/30 , A23L33/15 , A23L33/16 , A23V2002/00 , A61K2300/00 , A23V2250/71 , A23V2250/211 , A23V2250/704 , A23V2250/712 , A23V2250/708 , A23V2250/702 , A23V2250/705 , A23V2250/1578 , A23V2250/1592 , A23V2250/1642 , A23V2250/1608 , A23V2250/1586 , A23V2250/16 , A23V2250/1588 , A23V2250/156 , A23V2250/70
摘要： Multi-vitamin and mineral supplements for administration to non-lactating women, which comprise specific regimens of vitamins and minerals tailored to meet the physiological needs of said women. Methods for optimizing the health of women by providing multi-vitamin and mineral supplements which are specifically tailored to achieve optimal regulation of growth, maintenance and repair of body tissue during specific stages of life with minimal side effects. Methods for formulating a multi-vitamin and mineral supplement that optimize the health of a woman and which comprise identifying life stages which correlate to specific nutritional requirements as a result of varying physiological conditions during a lifetime and selecting specific types and optimal amounts of vitamins and minerals for said life stages.
摘要翻译： 多种维生素和矿物质补充剂用于非哺乳妇女的管理，其中包括针对所述妇女的生理需要量身定制的维生素和矿物质的具体方案。 通过提供多种维生素和矿物质补充剂来优化妇女健康的方法，这些补充剂专门用于在生命的特定阶段实现人体组织的生长，维持和修复的最佳调节，并具有最小的副作用。 制备多种维生素和矿物质补充剂的方法，其优化女性的健康，其包括鉴定生命周期中与不同生理条件相关的特定营养需求的生命阶段，并选择特定类型和最佳量的维生素和矿物质 对于生命阶段
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公开(公告)号：US06352713B1
公开(公告)日：2002-03-05
申请号：US09451849
申请日：1999-12-01
IPC分类号： A61K928
CPC分类号： A61K33/30 , A23L33/15 , A23L33/16 , A23V2002/00 , A61K9/0056 , A23V2250/708 , A23V2250/7052 , A23V2250/7106 , A23V2250/712 , A23V2250/1592 , A23V2250/1588 , A23V2250/161 , A23V2250/71 , A23V2250/1642 , A61K2300/00 , A23V2250/211 , A23V2250/704 , A23V2250/702 , A23V2250/705 , A23V2250/156 , A23V2250/70 , A23V2250/1578 , A23V2250/1608 , A23V2250/1586 , A23V2250/16
摘要： The present inventive subject matter is directed to novel chewable prenatal nutritional supplements which contain vitamin C, as well as novel methods for providing optimal vitamin C supplementation to pregnant women. The present invention is also directed to novel compositions and methods for providing nutritional supplementation to individuals planning to conceive a child.
摘要翻译： 本发明主题涉及含有维生素C的新型咀嚼产前营养补充剂，以及用于向孕妇提供最佳维生素C的新方法。 本发明还涉及用于向计划设想孩子的个人提供营养补充的新型组合物和方法。
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公开(公告)号：US06696083B1
公开(公告)日：2004-02-24
申请号：US09016786
申请日：1998-01-30
IPC分类号： A61K952
CPC分类号： A61K31/714 , A61K31/01 , A61K31/015 , A61K31/355 , A61K31/375 , A61K31/4415 , A61K31/51 , A61K38/063 , A61K45/06
摘要： The efficacy of vitamins and other nutritional agents in treating and preventing various disease states is improved by administering therapeutically effective levels of these agents on a substantially continuous, 24-hour basis. The concentration of lipid peroxides formed by the autoxidation of lipids, and the concentration of oxygen free radicals, are reduced by continuously administering antioxidant agents. The regeneration of nerve tissue is improved by continuously administering at least one pharmaceutically-acceptable B complex vitamin.
摘要翻译： 通过在基本上连续的24小时的基础上施用治疗有效量的这些药剂来改善维生素和其它营养剂治疗和预防各种疾病状态的功效。 通过持续施用抗氧化剂，减少通过脂质的自动氧化形成的脂质过氧化物的浓度和氧自由基的浓度。 通过连续施用至少一种药学上可接受的B复合维生素来改善神经组织的再生。
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公开(公告)号：US5296232A
公开(公告)日：1994-03-22
申请号：US882537
申请日：1992-05-13
CPC分类号： A61K9/5084 , A61K9/5078 , Y10S514/929 , Y10S514/962 , Y10S514/963
摘要： A controlled-release organic nitrate formulation for once-per-day oral administration is provided by spheres having a core which includes an organic nitrate, and a membrane surrounding the core composed of a pharmaceutically acceptable, film forming polymer. The film forming polymer is effective to permit release of the organic nitrate from the spheres, over a daily dosing period, at a rate that achieves a therapeutically effective level of the organic nitrate, while effecting a drug holiday towards a latter portion of the daily dosing period so as not to induce tolerance.
摘要翻译： 用于每日一次口服给药的控释有机硝酸盐制剂由具有核心的球体提供，所述核心包括有机硝酸盐，以及围绕由药学上可接受的成膜聚合物构成的核心的膜。 成膜聚合物有效地允许有机硝酸盐在每天的给药期间以达到治疗有效水平的有机硝酸盐的速率从球体中释放，同时对日剂量的后一部分进行药物假期 期间不引起宽容。
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公开(公告)号：US5445829A
公开(公告)日：1995-08-29
申请号：US898539
申请日：1992-06-15
CPC分类号： A61K9/5084 , A61K9/5078 , Y10S514/96 , Y10S514/961 , Y10S514/962 , Y10S514/963 , Y10S514/964
摘要： An extended release pharmaceutical formulation adapted to approach zero order release of drug over a 12 to at least 24 hour period, comprised of a mixture of 0 to about 50% of an immediate release particle containing a drug, inert substrate and binder, coated with talc and up to 100% of an extended release particle comprising the immediate release particle coated with a dissolution modifying system containing plasticizers and a film forming agent.
摘要翻译： 适于在12至24小时内接近零级释放药物的延长释放药物制剂，其包含0至约50％的含有药物，惰性底物和粘合剂的即时释放颗粒的混合物，其中涂覆有滑石 和高达100％的包含立体释放颗粒的延长释放颗粒，其包被含有增塑剂和成膜剂的溶解改性体系。
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公开(公告)号：US5133974A
公开(公告)日：1992-07-28
申请号：US469210
申请日：1990-01-24
CPC分类号： A61K9/5084 , A61K9/5078 , Y10S514/96 , Y10S514/961 , Y10S514/962 , Y10S514/963 , Y10S514/964
摘要： An extended release pharmaceutical formulation adapted to approach zero order release of drug over a 12 to at least 24 hour period, comprised of a mixture of 0 to aobut 50% of an immediate release particle containing a drug, inert substrate and binder, coated with talc and up to 100% of an extended release particle comprising the immediate release particle coated with a dissolution modifying system containing plasticizers and a film forming agent.
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公开(公告)号：US4973480A
公开(公告)日：1990-11-27
申请号：US370875
申请日：1989-06-23
IPC分类号： A61K9/48
CPC分类号： A61K9/4891
摘要： A tamper evident pharmaceutical capsule which contains an active agent. The capsule is coated on its external surfaces to provide an indication of tampering.
摘要翻译： 一种含有活性剂的防篡改药物胶囊。 胶囊被涂在其外表面上以提供篡改的指示。
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9.发明授权Oral once-per-day organic nitrate formulation which does not induce tolerance 失效口服每日一次有机硝酸盐制剂，不诱导耐受
公开(公告)号：US5122384A
公开(公告)日：1992-06-16
申请号：US349533
申请日：1989-05-05
CPC分类号： A61K9/5084 , A61K9/5078 , Y10S514/929 , Y10S514/962 , Y10S514/963
摘要： A controlled-release organic nitrate formulation for once-per-day oral administration is provided by spheres having a core which includes an organic nitrate, and a membrane surrounding the core composed of a pharmaceutically acceptable, film forming polymer. The film forming polymer is effective to permit release of the organic nitrate from the spheres, over a daily dosing period, at a rate that achieves a therapeutically effective level of the organic nitrate, while effecting a drug holiday towards a latter portion of the daily dosing period so as not to induce tolerance.
摘要翻译： 用于每日一次口服给药的控释有机硝酸盐制剂由具有核心的球体提供，所述核心包括有机硝酸盐，以及围绕由药学上可接受的成膜聚合物构成的核心的膜。 成膜聚合物有效地允许有机硝酸盐在每天的给药期间以达到治疗有效水平的有机硝酸盐的速率从球体中释放，同时对日剂量的后一部分进行药物假期 期间不引起宽容。
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公开(公告)号：US4844906A
公开(公告)日：1989-07-04
申请号：US30465
申请日：1987-03-25
IPC分类号： A61K9/48
CPC分类号： A61K9/4891
摘要： A tamper evident pharmaceutical capsule which contains an active agent. The capsule is coated on its external surfaces to provide an indication of tampering.
摘要翻译： 一种含有活性剂的防篡改药物胶囊。 胶囊被涂在其外表面上以提供篡改的指示。
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