摘要:
Methods for size fractionating nucleic acid molecules, using glass fiber filtration columns are described. The methods are useful in many downstream applications including array-based comparative genomic hybridization (aCGH), PCR-based sequencing, somatic genotypic with polymorphic markers, etc.
摘要:
This invention relates to methods and kits for collecting DNA from nucleic acid capture materials such as polymeric membranes at low ionic strength. The methods and kits can be used to obtain DNA for use in subsequent procedures, such as amplification and labeling reactions while reducing the co-purification of contaminants.
摘要:
Devices and methods for isolating nucleic acid are disclosed herein. In particular, the isolation of total cellular RNA is discussed. Additionally, devices and methods for reducing genomic DNA in a biological sample without introducing harmful contaminants, and without significantly increasing the time required for the overall procedure being performed on a sample are presented.
摘要:
This invention relates to methods and kits for collecting different biopolymers from a single sample, such as RNA and genomic DNA. The methods and kits can be used for generating targets for array-based assays such as gene expression assays and comparative genome hybridization assays which can be performed in parallel on the same or different arrays.
摘要:
Devices and methods for isolating nucleic acid are disclosed herein. In particular, the isolation of total cellular RNA is discussed. Additionally, devices and methods for reducing genomic DNA in a biological sample without introducing harmful contaminants, and without significantly increasing the time required for the overall procedure being performed on a sample are presented.
摘要:
This invention relates to devices, systems, methods, and kits for collecting subcellular components from a biological sample. In one aspect, invention pertains to the isolation of total cellular RNA from a biological material, such as plant tissue.