公开(公告)号：US4274964A

公开(公告)日：1981-06-23

申请号：US65075

申请日：1979-08-09

申请人： Gerd Krick ,  Peter Konang ,  Jan-Erik Sigdell ,  Klaus Heilmann

发明人： Gerd Krick ,  Peter Konang ,  Jan-Erik Sigdell ,  Klaus Heilmann

IPC分类号： A61M1/22 ,  B01D63/00 ,  B01D63/14 ,  B01D31/00

CPC分类号： B01D61/28 ,  B01D63/06 ,  B01D63/14 ,  Y10T156/1015

摘要： A dialyzer is formed by first placing a film strip into a membrane hose and then simultaneously folding the hose and a netting intermediate layer so that the folds of the hose and the folds of the netting extend crosswise relative to each other in a mutually interlocking manner. The facing ends of the hose layers are then sealed with a curable sealing compound and severed. Then the film strips are withdrawn from the hoses in the so formed package. The resulting product is a dialyzer or hemofilter, depending on the type of membrane hose used, in which the facing ends of the membrane hoses are open for the passage of blood therethrough, after the withdrawal of the film, and in which the netting layers are located between adjacent hoses.

摘要翻译： 通过首先将膜条放置在膜软管中，然后同时折叠软管和网状中间层，使得软管的折叠和网的折叠以相互互锁的方式相对于彼此横向延伸，形成透析器。 然后将软管层的相对端用可固化的密封化合物密封并切断。 然后将薄膜条从如此形成的包装中的软管中取出。 所得到的产品是透析器或血液滤膜器，取决于所用的膜软管的类型，其中膜软管的面对端打开以使血液通过其中，在膜退出之后，其中网状层是 位于相邻软管之间。

公开(公告)号：US4345999A

公开(公告)日：1982-08-24

申请号：US191378

申请日：1980-09-29

申请人： Jan-Erik Sigdell ,  Gerd Krick

发明人： Jan-Erik Sigdell ,  Gerd Krick

IPC分类号： A61M1/14 ,  A61M1/16 ,  A61M1/18 ,  A61M1/36 ,  B01D61/20 ,  B01D61/30 ,  B01D63/02 ,  B01D65/00 ,  B01D19/00 ,  B01D31/00

CPC分类号： A61M1/3627 ,  B01D61/20 ,  B01D61/30 ,  B01D63/02 ,  B01D65/00 ,  A61M1/16 ,  B01D2313/10

摘要： Air or gas is prevented from entering into the exchange zone of an artificial organ such as an artificial kidney, dialyzer, or hemofilter. For this purpose a separating path is arranged in parallel with the artificial organ or with the exchange zone or other operative portion of the artificial organ between the liquid inflow and outflow conduits. This parallel path is provided with a high flow resistance for the liquid and with a low flow resistance for the air. Such differential flow resistance may, for example, be accomplished by apertures, gas permeable materials, and eddy chambers. The gas separating path is incorporated as an integral part of the artificial organ or as an integral part of the liquid inflow and outflow conduits. According to several embodiments, an enlargement is provided in the separating path or conduit in which the liquid may "rise and dwell" to enhance air separation before the liquid flows into the operative portion of the artificial organ.

摘要翻译： 防止空气或气体进入诸如人造肾脏，透析器或血液滤膜器的人造器官的交换区。 为此目的，分离路径与人造器官或人造器官的交换区域或其他操作部分平行布置在液体流入和流出管道之间。 该平行路径具有用于液体的高流动阻力并且具有用于空气的低流动阻力。 这种差动流动阻力可以例如通过孔，气体可渗透材料和涡流室来实现。 气体分离路径作为人造器官的整体部分或作为液体流入和流出管道的组成部分结合。 根据若干实施例，在液体流入人造器官的手术部分之前，液体可能在其中“上升和停留”的分离路径或导管中提供增大以增强空气分离。

公开(公告)号：US4172794A

公开(公告)日：1979-10-30

申请号：US900660

申请日：1978-04-27

申请人： Jan-Erik Sigdell

发明人： Jan-Erik Sigdell

IPC分类号： A61M1/18 ,  B01D63/02 ,  B01D31/00

CPC分类号： B01D63/02 ,  B01D63/022

摘要： A hollow fiber dialyser comprises a webbing of hollow fibers. A loose warphread at each end of a webbing wound on a core, acts as a wick barrier to prevent sealant from leaking into the interstices between the hollow fibers. A tight warp thread nearest the open ends of the fibers pinches off the free inner cross section of each hollow fiber to prevent sealant from penetrating into the hollow fibers.

摘要翻译： 中空纤维透析器包括中空纤维织带。 缠绕在芯上的织带的每个端部处的松散的经线用作灯芯屏障，以防止密封剂泄漏到中空纤维之间的间隙中。 最接近纤维的开口端的紧密经线夹住每个中空纤维的自由内部横截面，以防止密封剂渗入中空纤维。

公开(公告)号：US4141835A

公开(公告)日：1979-02-27

申请号：US840758

申请日：1977-10-11

申请人： Wilfried Schael ,  Jan-Erik Sigdell ,  Gerd E. Krick

发明人： Wilfried Schael ,  Jan-Erik Sigdell ,  Gerd E. Krick

IPC分类号： A61M1/18 ,  B01D63/02 ,  B01D31/00

CPC分类号： B01D63/02 ,  B01D2313/08 ,  B01D2313/21

摘要： The present mass transfer apparatus between two media is especially adapted to blood dialysis. To assure an undisturbed flow of the blood through the dialyser and to avoid coagulation all flow channels are shaped to avoid dead corners and choking zones so that the blood is prevented from forming wakes or so-called "dead waters" in its flow path. For this purpose a hollow space is formed adjacent to the open ends of the hollow fibers. The inlet and/or outlet to this hollow space may extend radially axially or tangentially.

摘要翻译： 两种介质之间的传质装置特别适用于血液透析。 为了确保血液通过透析器不受干扰地流动并避免凝结，所有流动通道被成形以避免死角和阻塞区域，从而防止血液在其流动路径中形成醒来或所谓的“死水”。 为此，在中空纤维的开口端附近形成中空空间。 该中空空间的入口和/或出口可径向轴向或切向延伸。