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公开(公告)号：US20220226337A1
公开(公告)日：2022-07-21
申请号：US17550591
申请日：2021-12-14
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： A61K31/5377 , A61K31/343 , A61K31/353 , A61K31/357 , A61K31/416 , A61K31/4375 , A61K31/4709 , A61K31/513 , A61K31/519 , A61K31/538 , A61K31/541 , A61K45/06 , C07D295/00 , C07D307/87 , C07D319/18 , C07D405/10 , C07D407/10 , C07D413/14 , C07D471/04
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号：US20200155563A1
公开(公告)日：2020-05-21
申请号：US16667373
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： A61K31/5377 , A61K31/541 , A61K45/06 , C07D405/10 , A61K31/4709 , A61K31/357 , C07D319/18 , C07D413/14 , A61K31/513 , C07D307/87 , A61K31/343 , C07D295/00 , A61K31/538 , C07D407/10 , A61K31/353 , A61K31/416 , C07D471/04 , A61K31/4375 , A61K31/519
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号：US20200155538A1
公开(公告)日：2020-05-21
申请号：US16667306
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： A61K31/47 , A61K45/06 , C07D215/14 , C07D401/10 , A61K31/4709 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D401/14 , C07D407/14 , A61K31/506 , A61K31/501 , A61K31/5355 , C07D413/12 , C07D417/12 , A61K31/541 , A61K31/517 , A61K31/4375 , C07D471/04 , C07D487/04 , A61K31/519
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号：US10479770B2
公开(公告)日：2019-11-19
申请号：US15711875
申请日：2017-09-21
发明人： Jayaraman Chandrasekhar , Devan Naduthambi , Leena Patel , Stephane Perreault , Gary Phillips , Kassandra F. Sedillo , Nicholas Alexander Till , Jennifer Anne Treiberg , William J. Watkins , Julian A. Codelli , Joshua J. Van Veldhuizen
IPC分类号： C07D235/08 , C07D413/14 , C07D413/04 , A61K31/4184 , A61K31/5377 , A61P35/02 , A61P35/04 , A61K45/06
摘要： The present application provides the compounds of formula I or pharmaceutically acceptable salts, isomers, tautomer, or a mixture thereof, wherein t, R1, R2, R3, R4, and R6 are as described herein.
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公开(公告)号：US12053462B2
公开(公告)日：2024-08-06
申请号：US17379175
申请日：2021-07-19
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D215/02 , A61K31/4375 , A61K31/47 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D215/18 , C07D401/04 , C07D413/04 , C07D417/14 , C07D475/02 , C07D491/04 , C07D491/06 , C07D491/08 , C07D498/10 , C07D513/04
CPC分类号： A61K31/47 , A61K31/4375 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D215/18 , C07D401/04 , C07D413/04 , C07D417/14 , C07D475/02 , C07D491/04 , C07D491/06 , C07D491/08 , C07D498/10 , C07D513/04
摘要： The present disclosure provides a compound of Formula (I):
or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.-
公开(公告)号：US11174256B2
公开(公告)日：2021-11-16
申请号：US16667532
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D471/04 , A61K31/437 , A61K31/541
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号：US20200165248A1
公开(公告)日：2020-05-28
申请号：US16667532
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D471/04 , A61K31/541
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号：US20180086719A1
公开(公告)日：2018-03-29
申请号：US15711875
申请日：2017-09-21
发明人： Jayaraman Chandrasekhar , Devan Naduthambi , Leena Patel , Stephane Perreault , Gary Phillips , Kassandra F. Sedillo , Nicholas Alexander Till , Jennifer Anne Treiberg , William J. Watkins
IPC分类号： C07D235/08 , A61K31/4184
CPC分类号： C07D235/08 , A61K31/4184 , A61K31/5377 , A61K45/06 , A61K2300/00 , A61P35/02 , A61P35/04 , C07D413/04 , C07D413/14
摘要： The present application provides the compounds of formula I or pharmaceutically acceptable salts, isomers, tautomer, or a mixture thereof, wherein t, R1, R2, R3, R4, and R6 are as described herein.
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公开(公告)号：US20220152014A1
公开(公告)日：2022-05-19
申请号：US17508267
申请日：2021-10-22
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： A61K31/47 , A61K31/352 , A61K31/4709 , A61K31/497 , A61K31/501 , A61K31/513 , A61K31/5377 , A61K31/541 , C07D215/14 , C07D311/58 , C07D401/10 , C07D403/10 , C07D405/10 , C07D413/12 , C07D413/14 , C07D417/10 , C07D471/04 , C07D519/00
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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公开(公告)号：US20200163953A1
公开(公告)日：2020-05-28
申请号：US16667572
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： A61K31/47 , A61K31/541 , C07D215/14 , C07D413/12 , A61K31/5377 , A61K31/513 , C07D401/10 , A61K31/4709 , C07D417/10 , C07D403/10 , A61K31/497 , A61K31/501 , C07D405/10 , C07D413/14 , C07D471/04 , C07D519/00 , C07D311/58 , A61K31/352
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
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