公开(公告)号：US06329148B1

公开(公告)日：2001-12-11

申请号：US09505250

申请日：2000-02-15

申请人： Glenn D. Rosen ,  Peter Kao

发明人： Glenn D. Rosen ,  Peter Kao

IPC分类号： C12Q168

CPC分类号： A61K38/177 ,  A61K31/365 ,  A61K38/191 ,  A61K2300/00

摘要： A synergistic combination of ligands that interact with death domain receptors, and diterpenoid triepoxides is used to increase tumor cell killing by induction of apoptosis. Ligands useful in the invention include TRAIL, TNF-&agr;, analogs thereof, stabilized multimers thereof, mimetics, etc. Of particular interest are combined therapy with the diterpenoid triepoxides triptolide and derivatives and analogs thereof.

摘要翻译： 与死亡域受体相互作用的配体和二萜类三环氧化物的协同组合用于通过诱导凋亡来增加肿瘤细胞杀伤。 可用于本发明的配体包括TRAIL，TNF-α，其类似物，稳定的多聚体，模拟物等。特别令人感兴趣的是与二萜类三环氧化物雷公藤内酯及其衍生物和类似物的组合治疗。

公开(公告)号：US20190209917A1

公开(公告)日：2019-07-11

申请号：US15867478

申请日：2018-01-10

申请人： Peter Kao

发明人： Peter Kao

IPC分类号： A63F9/20

CPC分类号： A63F9/20 ,  A63F2250/50

摘要： The present application discloses a domino structure system comprising a track, a plurality of rods, a plurality of dominoes, a plurality of stoppers and at least one stand. The track comprises a left rail and a right rail. Each of the rods is coupled to the left rail at rate end and to the right ail at another end. The plurality of dominoes is rotatably coupled to the plurality of rods. The plurality of stoppers is capable of stopping the plurality of dominoes when the plurality of dominoes is perpendicular to the track. The at least one stand comprises a base, a column and a supporter, the column is coupled to the base, the supporter is coupled to the column, wherein the supporter is capable of supporting the track. A domino structure is also disclosed.

公开(公告)号：US20110270149A1

公开(公告)日：2011-11-03

申请号：US13101240

申请日：2011-05-05

申请人： John Faul ,  Toshihiko Nishimura ,  Peter Kao ,  Ronald Pearl

发明人： John Faul ,  Toshihiko Nishimura ,  Peter Kao ,  Ronald Pearl

IPC分类号： A61M1/00

CPC分类号： A61F2/06 ,  A61B5/026 ,  A61B17/11 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2017/1139 ,  A61M1/3653 ,  A61M1/3655 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2230/06 ,  A61M2230/202 ,  A61M2230/205 ,  A61M2230/30

摘要： A long-term implantable arterio-venous shunt device or creation of a fistula is provided that can be used as a therapeutic method for treating chronic obstructive pulmonary disease (COPD). The shunt device is implanted between an artery and a vein, preferably between a peripheral artery and the inferior vena cava. The shunt device and method of creating a fistula increases cardiac output and decreases the systemic vascular resistance and allows a blood flow rate through the shunt device of at least 5 ml/min after the implantation. Based on the effects of the method and device to the respiratory, cardiac and circulatory system, the method and device are beneficial as a therapy to patients with problems or conditions related to these systems.

摘要翻译： 提供长期植入式动静脉分流装置或瘘管的产生，其可用作治疗慢性阻塞性肺病（COPD）的治疗方法。 分流装置植入动脉和静脉之间，优选植入外周动脉和下腔静脉之间。 创建瘘管的分流装置和方法增加心输出量并降低全身血管阻力，并且允许在植入后通过分流装置的血流速度至少为5ml / min。 基于方法和装置对呼吸，心脏和循环系统的影响，该方法和装置作为对与这些系统相关的问题或病症的患者的治疗是有益的。

公开(公告)号：US11462951B1

公开(公告)日：2022-10-04

申请号：US17405855

申请日：2021-08-18

申请人： Peter Kao

发明人： Peter Kao

IPC分类号： A47J36/24 ,  H02J50/60 ,  H02J50/10

摘要： A method for distinguishing metal objects from a heating cup and a wireless charging device using the method are disclosed. The wireless charging device includes a housing, a power unit, a power transmitter, a current measuring unit, a Q factor measuring unit, a controller, and a temperature detector. The wireless charging device can distinguish metal objects from a heating cup by both current in the power transmitter and the Q factor of the power transmitter. If the heating cup is confirmed, a higher power will be provided to a metal heating layer of the heating cup to heat the liquid in the heating cup; otherwise, a lower power will be provided to charge general electronic devices having a power receiving element.

公开(公告)号：US20170265631A1

公开(公告)日：2017-09-21

申请号：US15076622

申请日：2016-03-21

申请人： Peter Kao

发明人： Peter Kao

IPC分类号： A45F3/12 ,  A45F3/04

CPC分类号： A45F3/12 ,  A45F3/047 ,  A45F2003/122

摘要： A backpack includes a pack body, two length-adjustable shoulder straps extended from the pack body for allowing the wearer to wear the pack body at the wearer's back, and a suspension arrangement which includes a resilient unit provided between the pack body and the shoulder straps for absorbing a bounding force of the pack body. Therefore, the resilient unit allows a relative movement of the pack body with respect to each of the shoulder straps but minimizes the relative movement of the pack body by absorbing the bounding force of the pack body. The resilient unit is also arranged for evenly distributing a loading force of the pack body to each of the shoulder straps, such that the resilient unit absorbs the bounding force of the pack body at different directions so as to balance the uneven loading force at the pack body.

公开(公告)号：US08574185B2

公开(公告)日：2013-11-05

申请号：US13101240

申请日：2011-05-05

申请人： John Faul ,  Toshihiko Nishimura ,  Peter Kao ,  Ronald Pearl

发明人： John Faul ,  Toshihiko Nishimura ,  Peter Kao ,  Ronald Pearl

IPC分类号： A61M19/00

CPC分类号： A61F2/06 ,  A61B5/026 ,  A61B17/11 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2017/1139 ,  A61M1/3653 ,  A61M1/3655 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2230/06 ,  A61M2230/202 ,  A61M2230/205 ,  A61M2230/30

摘要： A long-term implantable arterio-venous shunt device or creation of a fistula is provided that can be used as a therapeutic method for treating chronic obstructive pulmonary disease (COPD). The shunt device is implanted between an artery and a vein, preferably between a peripheral artery and the inferior vena cava. The shunt device and method of creating a fistula increases cardiac output and decreases the systemic vascular resistance and allows a blood flow rate through the shunt device of at least 5 ml/min after the implantation. Based on the effects of the method and device to the respiratory, cardiac and circulatory system, the method and device are beneficial as a therapy to patients with problems or conditions related to these systems.

摘要翻译： 提供长期植入式动静脉分流装置或瘘管的产生，其可用作治疗慢性阻塞性肺病（COPD）的治疗方法。 分流装置植入动脉和静脉之间，优选植入外周动脉和下腔静脉之间。 创建瘘管的分流装置和方法增加心输出量并降低全身血管阻力，并且允许在植入后通过分流装置的血流速度至少为5ml / min。 基于方法和装置对呼吸，心脏和循环系统的影响，该方法和装置作为对与这些系统相关的问题或病症的患者的治疗是有益的。

公开(公告)号：US08551032B2

公开(公告)日：2013-10-08

申请号：US13654273

申请日：2012-10-17

申请人： John Faul ,  Toshihiko Nishimura ,  Peter Kao ,  Ronald Pearl

发明人： John Faul ,  Toshihiko Nishimura ,  Peter Kao ,  Ronald Pearl

IPC分类号： A61M19/00

CPC分类号： A61F2/06 ,  A61B5/026 ,  A61B17/11 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2017/1139 ,  A61M1/3653 ,  A61M1/3655 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2230/06 ,  A61M2230/202 ,  A61M2230/205 ,  A61M2230/30

摘要： A long-term implantable arterio-venous shunt device or creation of a fistula is provided that can be used as a therapeutic method for treating chronic obstructive pulmonary disease (COPD). The shunt device is implanted between an artery and a vein, preferably between a peripheral artery and the inferior vena cava. The shunt device and method of creating a fistula increases cardiac output and decreases the systemic vascular resistance and allows a blood flow rate through the shunt device of at least 5 ml/min after the implantation. Based on the effects of the method and device to the respiratory, cardiac and circulatory system, the method and device are beneficial as a therapy to patients with problems or conditions related to these systems.

摘要翻译： 提供长期植入式动静脉分流装置或瘘管的产生，其可用作治疗慢性阻塞性肺病（COPD）的治疗方法。 分流装置植入动脉和静脉之间，优选植入外周动脉和下腔静脉之间。 创建瘘管的分流装置和方法增加心输出量并降低全身血管阻力，并且允许在植入后通过分流装置的血流速度至少为5ml / min。 基于方法和装置对呼吸，心脏和循环系统的影响，该方法和装置作为对与这些系统相关的问题或病症的患者的治疗是有益的。

公开(公告)号：US20120010556A1

公开(公告)日：2012-01-12

申请号：US13241497

申请日：2011-09-23

申请人： John Faul ,  Toshihiko Nishimura ,  Peter Kao ,  Ronald Pearl

发明人： John Faul ,  Toshihiko Nishimura ,  Peter Kao ,  Ronald Pearl

IPC分类号： A61M1/00

CPC分类号： A61B17/11 ,  A61B5/026 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2017/1139 ,  A61F2/06 ,  A61M1/3653 ,  A61M1/3655 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2230/06 ,  A61M2230/202 ,  A61M2230/205 ,  A61M2230/30

摘要： A long-term implantable arterio-venous shunt device is provided that can be used as a therapeutic method. The shunt device is implanted between an artery and a vein, preferably between the aorta and the inferior vena cava. The shunt device decreases the systemic vascular resistance and allows a blood flow rate through the shunt device of at least 5 ml/min after the implantation. The blood flow rate could be controlled either via an open loop or a closed loop control means. The shunt device could also be a self-adjustable shunt device to self-adjust its structure to control the blood flow rate through its lumen. Based on the effects of the shunt device to the respiratory, cardiac and circulatory system, the implantable shunt device could be beneficial as a therapy to patients with problems or conditions related to these systems.

摘要翻译： 提供可用作治疗方法的长期可植入动静脉分流装置。 分流装置植入动脉和静脉之间，优选在主动脉和下腔静脉之间。 分流装置降低全身血管阻力，并允许植入后通过分流装置的血流速度至少为5ml / min。 可以通过开环或闭环控制装置来控制血液流量。 分流装置也可以是自调节分流装置，以自我调节其结构以控制通过其管腔的血液流速。 基于分流装置对呼吸，心脏和循环系统的影响，可植入分流装置可作为对与这些系统相关的问题或病症的患者的治疗有益。

公开(公告)号：US20170265630A1

公开(公告)日：2017-09-21

申请号：US15232772

申请日：2016-08-09

申请人： Peter Kao

发明人： Peter Kao

IPC分类号： A45F3/04

CPC分类号： A45F3/047 ,  A45C13/02 ,  A45F3/12

摘要： A backpack includes a pack body, two shoulder straps extended from the pack body for allowing the wearer to wear the pack body at the wearer's back, and a suspension arrangement which includes a resilient unit provided between the pack body and the shoulder straps for absorbing a bounding force of the pack body. Therefore, the resilient unit allows a relative movement of the pack body with respect to each of the shoulder straps but minimizes the relative movement of the pack body by absorbing the bounding force of the pack body. The resilient unit is also arranged for evenly distributing a loading force of the pack body to each of the shoulder straps, such that the resilient unit absorbs the bounding force of the pack body at different directions so as to balance the uneven loading force at the pack body.

公开(公告)号：US20130041306A1

公开(公告)日：2013-02-14

申请号：US13654273

申请日：2012-10-17

申请人： John Faul ,  Toshihiko Nishimura ,  Peter Kao ,  Ronald Pearl

发明人： John Faul ,  Toshihiko Nishimura ,  Peter Kao ,  Ronald Pearl

IPC分类号： A61M1/00

CPC分类号： A61F2/06 ,  A61B5/026 ,  A61B17/11 ,  A61B2017/00252 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2017/1139 ,  A61M1/3653 ,  A61M1/3655 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2230/06 ,  A61M2230/202 ,  A61M2230/205 ,  A61M2230/30

摘要： A long-term implantable arterio-venous shunt device or creation of a fistula is provided that can be used as a therapeutic method for treating chronic obstructive pulmonary disease (COPD). The shunt device is implanted between an artery and a vein, preferably between a peripheral artery and the inferior vena cava. The shunt device and method of creating a fistula increases cardiac output and decreases the systemic vascular resistance and allows a blood flow rate through the shunt device of at least 5 ml/min after the implantation. Based on the effects of the method and device to the respiratory, cardiac and circulatory system, the method and device are beneficial as a therapy to patients with problems or conditions related to these systems.