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    SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT
    1.
    发明申请
    SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT 有权
    用于递送治疗剂的系统和方法

    公开(公告)号：US20110275997A1

    公开(公告)日：2011-11-10

    申请号：US13101749

    申请日：2011-05-05

    申请人： Glenn R. Booma ,  Alessandro Pizzochero ,  J. Richard Gyory

    发明人： Glenn R. Booma ,  Alessandro Pizzochero ,  J. Richard Gyory

    IPC分类号： A61M37/00

    CPC分类号： A61M5/145 ,  A61M5/14248 ,  A61M31/00 ,  A61M35/00 ,  A61M37/00 ,  A61M2005/14506 ,  A61M2005/14513

    摘要： Devices, methods, and kits for delivering a therapeutic agent to a patient are disclosed herein. In one embodiment, an apparatus comprises a reservoir for containing a fluid, a first actuator, a transfer structure, and a second actuator. The first actuator has a first configuration and a second configuration and is configured to exert a first force on the reservoir when moved from its first configuration to its second configuration such that a first volume of fluid within the reservoir is communicated out of the fluid reservoir. The transfer structure is disposed between the first actuator and the reservoir and has a surface configured to engage the reservoir such that the first force exerted by the first actuator is distributed across a surface of the reservoir engaged by the transfer structure. The second actuator has a first configuration and a second configuration and is configured to exert a second force on the reservoir when the second actuator is moved from its first configuration to its second configuration such that a second volume of fluid within the reservoir is communication out of the fluid reservoir.

    摘要翻译： 本文公开了用于将治疗剂递送至患者的装置，方法和试剂盒。 在一个实施例中，装置包括用于容纳流体的储存器，第一致动器，转印结构和第二致动器。 第一致动器具有第一构造和第二构造，并且构造成当从其第一构型移动到其第二构造时在储存器上施加第一力，使得储存器内的第一体积的流体被连通出流体储存器。 转移结构设置在第一致动器和储存器之间，并且具有构造成与储存器接合的表面，使得由第一致动器施加的第一力分布在由传送结构接合的储存器的表面上。 第二致动器具有第一构造和第二构造，并且构造成当第二致动器从其第一构型移动到其第二构造时在储存器上施加第二力，使得储存器内的第二体积的流体从 流体储存器。

    Systems and methods for delivering a therapeutic agent
    2.
    发明授权
    Systems and methods for delivering a therapeutic agent 有权
    用于递送治疗剂的系统和方法

    公开(公告)号：US08337457B2

    公开(公告)日：2012-12-25

    申请号：US13101749

    申请日：2011-05-05

    申请人： Glenn R. Booma ,  Alessandro Pizzochero ,  J. Richard Gyory

    发明人： Glenn R. Booma ,  Alessandro Pizzochero ,  J. Richard Gyory

    IPC分类号： A61M37/00

    CPC分类号： A61M5/145 ,  A61M5/14248 ,  A61M31/00 ,  A61M35/00 ,  A61M37/00 ,  A61M2005/14506 ,  A61M2005/14513

    摘要： In one embodiment, an apparatus comprises a reservoir for containing a fluid, a first actuator, a transfer structure, and a second actuator. The first actuator is configured to exert a first force on the reservoir when moved from a first configuration to a second configuration such that a first volume of fluid within the reservoir is communicated out of the reservoir. The transfer structure is disposed between the first actuator and the reservoir and has a surface configured to engage the reservoir such that the first force exerted by the first actuator is distributed across a surface of the reservoir engaged by the transfer structure. The second actuator is configured to exert a second force on the reservoir when the second actuator is moved from a first configuration to a second configuration such that a second volume of fluid within the reservoir is communicated out of the fluid reservoir.

    摘要翻译： 在一个实施例中，装置包括用于容纳流体的储存器，第一致动器，转印结构和第二致动器。 第一致动器构造成当从第一构造移动到第二构造时在储存器上施加第一力，使得储存器内的第一体积的流体被传送出储存器。 转移结构设置在第一致动器和储存器之间，并且具有构造成与储存器接合的表面，使得由第一致动器施加的第一力分布在由传送结构接合的储存器的表面上。 第二致动器构造成当第二致动器从第一构造移动到第二构造时使第二压力在储存器上施加第二力，使得储存器内的第二体积的流体从流体储存器传出。

    SYSTEMS AND METHODS FOR DELIVERING A FLUID DRUG
    6.
    发明申请
    SYSTEMS AND METHODS FOR DELIVERING A FLUID DRUG 有权
    用于输送流体药物的系统和方法

    公开(公告)号：US20100240757A1

    公开(公告)日：2010-09-23

    申请号：US12594785

    申请日：2008-03-27

    申请人： Anthony Meehan ,  Glenn R. Booma ,  Gerd Schmieta ,  David L. Weissburg ,  Jonathan Belfort ,  Mekayla Beaver ,  Gary A. Meade

    发明人： Anthony Meehan ,  Glenn R. Booma ,  Gerd Schmieta ,  David L. Weissburg ,  Jonathan Belfort ,  Mekayla Beaver ,  Gary A. Meade

    IPC分类号： A61K31/195 ,  G01F11/00 ,  B65D47/08 ,  B65D37/00

    CPC分类号： A61M35/00 ,  G01F11/286

    摘要： Devices and methods for distributing a fluid, e.g., a fluid drug, are disclosed. Fluid-drug distribution can be advantageously utilized to help patients suffering from a disorder that affect fine motor skill usage, e.g., Parkinson's Disease. Some aspects are directed to dosing containers that are adapted to distribute one or more selected dosages of fluid from the container. In some instances, the containers are adapted to be operable by patients with hindered fingertip motor control to help dispense a fluid-drug, such as a fluid including carbidopa and levodopa. Other aspects are directed to a kit for distributing a fluid drug that can be stored with a longer shelf life in solid form. Also discussed herein are methods for distributing a fluid drug for treating a disorder such as Parkinson's Disease.

    摘要翻译： 公开了用于分配流体的装置和方法，例如流体药物。 流体药物分布可以有利地用于帮助患有影响精细运动技能使用的病症的患者，例如帕金森病。 一些方面针对适于从容器中分配一种或多种选定剂量的流体的剂量容器。 在一些情况下，容器适于由受阻指针马达控制的患者操作以帮助分配流体药物，例如包括卡比多巴和左旋多巴的流体。 其他方面涉及用于分配可以以更长的保质期储存的流体药物的固体形式的试剂盒。 本文还讨论了用于分配用于治疗诸如帕金森病之类疾病的流体药物的方法。

    Systems and methods for delivering a fluid drug
    7.
    发明授权
    Systems and methods for delivering a fluid drug 有权
    用于输送流体药物的系统和方法

    公开(公告)号：US08563013B2

    公开(公告)日：2013-10-22

    申请号：US12594785

    申请日：2008-03-27

    申请人： Anthony Meehan ,  Glenn R. Booma ,  Gerd Schmieta ,  David L. Weissburg ,  Jonathan Belfort ,  Mekayla Beaver ,  Gary A. Meade

    发明人： Anthony Meehan ,  Glenn R. Booma ,  Gerd Schmieta ,  David L. Weissburg ,  Jonathan Belfort ,  Mekayla Beaver ,  Gary A. Meade

    IPC分类号： A61K9/00

    CPC分类号： A61M35/00 ,  G01F11/286

    摘要： Devices and methods for distributing a fluid, e.g., a fluid drug, are disclosed. Fluid-drug distribution can be advantageously utilized to help patients suffering from a disorder that affect fine motor skill usage, e.g., Parkinson's Disease. Some aspects are directed to dosing containers that are adapted to distribute one or more selected dosages of fluid from the container. In some instances, the containers are adapted to be operable by patients with hindered fingertip motor control to help dispense a fluid-drug, such as a fluid including carbidopa and levodopa. Other aspects are directed to a kit for distributing a fluid drug that can be stored with a longer shelf life in solid form. Also discussed herein are methods for distributing a fluid drug for treating a disorder such as Parkinson's Disease.

    摘要翻译： 公开了用于分配流体的装置和方法，例如流体药物。 流体药物分布可以有利地用于帮助患有影响精细运动技能使用的病症的患者，例如帕金森病。 一些方面针对适于从容器中分配一种或多种选定剂量的流体的剂量容器。 在一些情况下，容器适于由受阻指针马达控制的患者操作以帮助分配流体药物，例如包括卡比多巴和左旋多巴的流体。 其他方面涉及用于分配可以以更长的保质期储存的流体药物的固体形式的试剂盒。 本文还讨论了用于分配用于治疗诸如帕金森病之类疾病的流体药物的方法。