摘要:
An inhaler comprising a housing to receive a strip having a plurality of blisters, each blister having a puncturable lid and containing a dose of medicament for inhalation by a user, a mouthpiece through which a dose of medicament is inhaled by a user, a cap to cover the mouthpiece and, a blister piercing element to pierce the lid of a blister is disclosed. The cap is rotatable to drive the strip to sequentially move each blister into alignment with the blister piercing element and an actuator is operable in response to rotation of the cap to cause the blister piercing element to puncture the lid of an aligned blister such that, when a user inhales through the mouthpiece, an airflow through the blister is generated to entrain the dose contained therein and carry it out of the blister and via the mouthpiece into the user's airway.
摘要:
An inhaler (1) including a blister strip (2) is proposed. The unused blister strip is stored in a spiral (16). After use, the blister strip is conveyed into another spiral (17). Both spirals share a common space within the inhaler and may be separated by a loose guiding element (18). The spirals and the guiding element may comprise protrusions (19) to reduce sliding friction. Additionally or alternatively, a lubricant (31) may be used to reduce friction.
摘要:
An inhaler is disclosed. It comprises a housing to receive a strip having a plurality of blisters, each blister having a breachable lid and containing a dose of medicament for inhalation by a user, an indexing wheel mounted in the housing rotatable to drive a strip to sequentially move blisters into alignment with a blister piercing member, a control element pivotally mounted to the housing and a drive mechanism configured to couple the control element to the indexing wheel during part of the rotation of the control element by a user so that the indexing wheel rotates together with the control element.
摘要:
An inhaler is disclosed. It comprises a housing to receive a strip having a plurality of blisters, each blister having a breachable lid and containing a dose of medicament for inhalation by a user, an indexing wheel mounted in the housing rotatable to drive a strip to sequentially move blisters into alignment with a blister piercing member, a control element pivotally mounted to the housing and a drive mechanism configured to couple the control element to the indexing wheel during part of the rotation of the control element by a user so that the indexing wheel rotates together with the control element.
摘要:
A method of coiling a strip of blisters for insertion into an inhalation device is disclosed. The method includes the steps of taking a preformed strip of blisters in which each blister contains a dose of medicament for inhalation by a user, manipulating the strip to impart a continuous curvature or a series of discrete creases to the strip; that allow the strip to form into a coiled shape. A strip which has been coiled according to the method is also disclosed, as is an inhalation device incorporating means for coiling a strip of blisters according to the invention.
摘要:
An inhaler is disclosed. The inhaler has a housing to receive an elongate strip of blisters each containing a dose of medicament and being sequentially movable into alignment with means for breaching a blister to enable a user to inhale said dose contained therein. The device has a spiral wound element within the housing that receives and coils said strip of blisters that have been breached.
摘要:
An inhaler is disclosed. It comprises a housing to receive an elongate strip of blisters each containing a dose of medicament and being sequentially movable into alignment with means for breaching a blister to enable a user to inhale said dose contained therein. The device comprises a spiral wound element within the housing that receives and coils said strip of blisters that have been breached.
摘要:
An inhaler is disclosed. It comprises a housing to receive an elongate strip of blisters each containing a dose of medicament and being sequentially movable into alignment with means for breaching a blister to enable a user to inhale said dose contained therein. The device comprises a spiral wound element within the housing that receives and coils said strip of blisters that have been breached.
摘要:
A needle-free injector device comprising a latch having a safe position which disables the triggering of the device, and a ready position which restrains movement of a dispensing member but enables triggering and a triggered position which permits movement of the dispensing member is disclosed. An additional safety mechanism blocks the triggering of the device until removed. A cap is provided to maintain the sterility and stability of the drug formulation and is configured such that the cap removal is required prior to placing the device in a ready to trigger state.
摘要:
Sheets or moulded bodies, for example particle board, are manufactured by hot pressing a lignocellulosic material in contact with an organic polyisocyanate and a wax release agent which is a vegetable wax, a modified vegetable oil, a microcrystalline wax or a mineral wax, said wax release agent having a melting point of at least 70.degree. C. Preferably the wax release agent is applied to the lignocellulosic material in the form of a dispersion in an aqueous emulsion of the polyisocyanate. The process facilitates the release of the sheets or moulded bodies from the caul plates or platens of the press.