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    BRAIDED IMPLANTABLE MEDICAL LEAD AND METHOD OF MAKING SAME
    1.
    发明申请
    BRAIDED IMPLANTABLE MEDICAL LEAD AND METHOD OF MAKING SAME 审中-公开
    可植入式医用引线及其制造方法

    公开(公告)号：US20110218602A1

    公开(公告)日：2011-09-08

    申请号：US12716519

    申请日：2010-03-03

    申请人： Greg Kampa ,  Dorab N. Sethna ,  Scott Salys ,  Keith Victorine

    发明人： Greg Kampa ,  Dorab N. Sethna ,  Scott Salys ,  Keith Victorine

    IPC分类号： A61N1/05 ,  H01R43/00

    CPC分类号： A61N1/05 ,  H01R43/00 ,  Y10T29/4921

    摘要： An implantable medical lead disclosed herein may include a longitudinally extending body, a helical anchor and a lead connector end. The longitudinally extending body may include a distal end, a proximal end, a braid-reinforced inner tubular layer extending between the proximal and distal ends, and an outer tubular layer extending between the proximal and distal ends. The braid-reinforced inner tubular layer may extend through the outer tubular layer in a coaxial arrangement. The helical anchor electrode may be operably coupled to a distal end of the braid-reinforced inner tubular layer. The lead connector end may be operably coupled to the proximal end of the body and include a pin contact operably coupled to a proximal end of the braid-reinforced tubular layer. Rotation of the pin contact relative to the lead connector end may cause rotation of the braid-reinforced inner tubular layer within the outer tubular layer, and the resulting rotation of the braid-reinforced inner tubular layer may cause rotation of the helical anchor electrode.

    摘要翻译： 本文公开的可植入医疗引线可以包括纵向延伸体，螺旋锚和引线连接器端。 纵向延伸体可以包括远端，近端，在近端和远端之间延伸的编织增强的内管状层，以及在近端和远端之间延伸的外管层。 编织增强的内部管状层可以以同轴布置延伸穿过外部管状层。 螺旋锚定电极可以可操作地联接到编织物增强的内部管状层的远端。 引导连接器端可以可操作地耦合到主体的近端，并且包括可操作地联接到编织增强管状层的近端的销接触。 销触点相对于引线连接器端部的旋转可能导致编织增强的内部管状层在外部管状层内的旋转，并且编织增强的内部管状层的最终旋转可能导致螺旋锚定电极的旋转。

    Implantable medical lead and method of making same
    3.
    发明授权
    Implantable medical lead and method of making same 有权
    可植入医用铅及其制作方法

    公开(公告)号：US08792996B2

    公开(公告)日：2014-07-29

    申请号：US12564518

    申请日：2009-09-22

    申请人： Dorab N. Sethna ,  Sean Matthew Desmond ,  Sergey Safarevich ,  Keith Victorine ,  Greg Kampa

    发明人： Dorab N. Sethna ,  Sean Matthew Desmond ,  Sergey Safarevich ,  Keith Victorine ,  Greg Kampa

    IPC分类号： A61N1/00 ,  A61N1/05

    CPC分类号： A61N1/05 ,  A61N1/056 ,  Y10T29/49117

    摘要： An implantable medical lead is disclosed herein. The lead may include a longitudinally extending body, an electrical conductor, a tube and an electrical component, such as, for example, an electrode for sensing or pacing, a defibrillation coil, a strain gage, a pressure sensor, a piezoelectric sensor, an integrated chip, an inductor, etc. The body may include a distal end and a proximal end. The electrical conductor may extend through the body between the proximal end and the distal end. The tube may be swaged about an outer circumferential portion of the electrical conductor. The electrical component may be on the body and electrically connected to the tube.

    摘要翻译： 本文公开了可植入医疗引线。 引线可以包括纵向延伸的主体，电导体，管和电部件，例如用于感测或起搏的电极，除颤线圈，应变计，压力传感器，压电传感器， 集成芯片，电感器等。主体可以包括远端和近端。 电导体可以在近端和远端之间延伸通过本体。 管可以围绕电导体的外周部分模锻。 电气部件可以在主体上并且电连接到管。

    IMPLANTABLE MEDICAL LEAD AND METHOD OF MAKING SAME
    5.
    发明申请
    IMPLANTABLE MEDICAL LEAD AND METHOD OF MAKING SAME 有权
    可植入医疗铅及其制造方法

    公开(公告)号：US20110071607A1

    公开(公告)日：2011-03-24

    申请号：US12564518

    申请日：2009-09-22

    申请人： Dorab N. Sethna ,  Sean Matthew Desmond ,  Sergey Safarevich ,  Keith Victorine ,  Greg Kampa

    发明人： Dorab N. Sethna ,  Sean Matthew Desmond ,  Sergey Safarevich ,  Keith Victorine ,  Greg Kampa

    IPC分类号： A61N1/05 ,  H01R43/00

    CPC分类号： A61N1/05 ,  A61N1/056 ,  Y10T29/49117

    摘要： An implantable medical lead is disclosed herein. The lead may include a longitudinally extending body, an electrical conductor, a tube and an electrical component, such as, for example, an electrode for sensing or pacing, a defibrillation coil, a strain gage, a pressure sensor, a piezoelectric sensor, an integrated chip, an inductor, etc. The body may include a distal end and a proximal end. The electrical conductor may extend through the body between the proximal end and the distal end. The tube may be swaged about an outer circumferential portion of the electrical conductor. The electrical component may be on the body and electrically connected to the tube.

    摘要翻译： 本文公开了可植入医疗引线。 引线可以包括纵向延伸的主体，电导体，管和电部件，例如用于感测或起搏的电极，除颤线圈，应变计，压力传感器，压电传感器， 集成芯片，电感器等。主体可以包括远端和近端。 电导体可以在近端和远端之间延伸通过本体。 管可以围绕电导体的外周部分模锻。 电气部件可以在主体上并且电连接到管。

    Implantable lead and method of making the same
    6.
    发明授权
    Implantable lead and method of making the same 有权
    可植入铅及其制作方法

    公开(公告)号：US08751018B1

    公开(公告)日：2014-06-10

    申请号：US11855064

    申请日：2007-09-13

    申请人： Dorab N. Sethna ,  Keith Victorine ,  Scott Salys

    发明人： Dorab N. Sethna ,  Keith Victorine ,  Scott Salys

    IPC分类号： A61N1/05

    CPC分类号： A61N1/05

    摘要： A method of manufacturing an implantable lead includes providing a core including at least one longitudinal lumen; providing a jacket comprising a reflowable material; positioning the core at least partially within the jacket; and, after positioning, applying heat to cause the material of the jacket to reflow and bond to the core. An implantable lead includes a core including at least one longitudinal lumen; and a jacket comprising a reflowable material. The core may be at least partially disposed within the jacket with the material of the jacket reflow-bonded to the core. The implantable lead may further include at least one lead component associated with at least one of the core and the jacket.

    摘要翻译： 制造可植入引线的方法包括提供包括至少一个纵向内腔的芯; 提供包括可回流材料的护套; 将芯部至少部分地定位在护套内; 并且在定位之后，施加热量以使夹套的材料回流并结合到芯部。 可植入引线包括：芯，其包括至少一个纵向内腔; 以及包括可回流材料的护套。 芯可以至少部分地设置在护套内，套管的材料回流焊接到芯上。 可植入引线还可以包括至少一个与芯和护套中的至少一个相关联的引线部件。

    CONNECTOR SLEEVE FOR A LEAD OF AN INTERNAL PULSE GENERATOR
    7.
    发明申请
    CONNECTOR SLEEVE FOR A LEAD OF AN INTERNAL PULSE GENERATOR 有权
    内部脉冲发生器引线的连接器套管

    公开(公告)号：US20130021040A1

    公开(公告)日：2013-01-24

    申请号：US13188116

    申请日：2011-07-21

    申请人： Li Jin ,  Hanson Chang ,  Keith Victorine ,  Tyler Strang ,  Armando M. Cappa

    发明人： Li Jin ,  Hanson Chang ,  Keith Victorine ,  Tyler Strang ,  Armando M. Cappa

    IPC分类号： G01R31/04 ,  H01R11/22

    CPC分类号： A61N1/3752 ,  H01R11/24 ,  H01R24/58

    摘要： Implementations of the present disclosure involve an internal pulse generator for administering electrotherapy via an implantable medical lead having a lead connector end on a proximal end of the lead. In addition, implementations involve testing of the medical lead at the proximal lead connector end to ensure proper placement of the lead, and an interface device for facilitating the connection of the proximal lead connector end to a testing device. The interface device may provide for one or more electrical connection points disposed on a connector sleeve. The connection points provide electrical communication between the lead connector end of the lead and one or more leads of a testing device in such a manner as to minimize potential damage to the lead connector end.

    摘要翻译： 本公开的实施方案涉及内部脉冲发生器，其用于通过在铅的近端具有引线连接器端的可植入医疗引线进行电疗。 此外，实施方案涉及在近端引线连接器端部处的医疗引线的测试，以确保引线的正确放置，以及用于便于将近端引线连接器端部连接到测试装置的接口装置。 接口装置可以提供设置在连接器套筒上的一个或多个电连接点。 连接点提供引线的引线连接器端与测试装置的一个或多个引线之间的电气连通，以便使对引线连接器端的潜在损害最小化。

    SYSTEM AND METHOD FOR DETECTION AND TREATMENT OF IRREGULAR METABOLIC FUNCTION
    8.
    发明申请
    SYSTEM AND METHOD FOR DETECTION AND TREATMENT OF IRREGULAR METABOLIC FUNCTION 审中-公开
    用于检测和治疗非正常代谢功能的系统和方法

    公开(公告)号：US20100298663A1

    公开(公告)日：2010-11-25

    申请号：US12469582

    申请日：2009-05-20

    申请人： Xiangqun Chen ,  Keith Victorine

    发明人： Xiangqun Chen ,  Keith Victorine

    IPC分类号： A61B5/00

    CPC分类号： A61B5/02055 ,  A61B5/0031 ,  A61B5/021 ,  A61B5/04001 ,  A61B5/0452 ,  A61B5/0456 ,  A61B5/0464 ,  A61B5/0816 ,  A61B5/11 ,  A61B5/14539 ,  A61B5/4035

    摘要： A system and method for detecting and treating irregular metabolic function. The systems and methods generally include an implantable medical device that measures various physiological parameters. Such physiological parameters generally provide an indication of the patient's metabolic rate, respiratory rate, and activity level. For example, the medical device may measure the patient's relative movement, or may measure the patient's oxygen consumption. These measures are then recorded, and the recorded data is used to determine the normal relationship between metabolic rate and other physiological parameters for that patient. The baseline relationship is then used to determine if the patient experiences an increase or decrease in metabolic rate that is not explained by changes in other physiological parameters. Further testing, and treatment if necessary, can be performed if the physiological parameters indicate irregular metabolic function.

    摘要翻译： 用于检测和治疗不规则代谢功能的系统和方法。 系统和方法通常包括测量各种生理参数的可植入医疗装置。 这种生理参数通常提供患者的代谢率，呼吸频率和活动水平的指示。 例如，医疗设备可以测量患者的相对运动，或者可以测量患者的氧气消耗。 然后记录这些措施，记录的数据用于确定该患者的代谢率与其他生理参数之间的正常关系。 然后使用基线关系来确定患者是否经历代谢率的增加或减少，这并不是通过其他生理参数的变化来解释的。 如果生理参数表示不规则的代谢功能，可以进行进一步的测试和必要时的治疗。

    Implantable lead/electrode delivery measurement and feedback system
    10.
    发明授权
    Implantable lead/electrode delivery measurement and feedback system 有权
    可植入铅/电极传输测量和反馈系统

    公开(公告)号：US08442620B2

    公开(公告)日：2013-05-14

    申请号：US12243674

    申请日：2008-10-01

    申请人： Enzo Silipo ,  Kyungmoo Ryu ,  Gene A. Bornzin ,  John W. Poore ,  Keith Victorine ,  Zoltan Somogyi ,  Nalin Perera

    发明人： Enzo Silipo ,  Kyungmoo Ryu ,  Gene A. Bornzin ,  John W. Poore ,  Keith Victorine ,  Zoltan Somogyi ,  Nalin Perera

    IPC分类号： A61B5/053 ,  A61B5/00

    CPC分类号： A61N1/05 ,  A61N1/08

    摘要： A lead implantation system with an introducer, a lead configured to engage with the introducer such that the introducer can convey the lead to a desired internal target location, and at least one sensor. The sensor is adapted to generate an indicator of desired engagement of the system with the desired target tissue location prior to engagement of the lead with the target tissue. Also a method of implanting an implantable patient lead including advancing a lead implantation assembly towards a desired target location along an introduction axis and monitoring at least one indicator of lead implantation assembly position along the lead introduction axis. At least one indicator can be generated by the lead implantation assembly. Advancing of the lead introduction assembly can be halted when the monitoring indicates contact with the desired target tissue. The patient lead can then be advanced towards the target tissue and fixed to the target tissue.

    摘要翻译： 一种具有引导器的引线植入系统，引线被构造成与导引器接合，使得导引器可将引线传送到期望的内部目标位置，以及至少一个传感器。 所述传感器适于在所述引线与所述目标组织接合之前产生具有期望的目标组织位置的所述系统期望接合的指示器。 还有一种植入可植入患者导线的方法，包括沿着引入轴线将引线植入组件推向所需目标位置，并且沿导线引入轴监测铅植入组件位置的至少一个指示器。 至少一个指示器可以由引线注入组件产生。 当监测指示与所需目标组织接触时，引导组件的推进可以停止。 然后可以将患者导线朝向目标组织推进并固定到靶组织。