-
公开(公告)号:US20130156754A1
公开(公告)日:2013-06-20
申请号:US13773485
申请日:2013-02-21
申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
IPC分类号: A61K39/395
CPC分类号: C07K16/283 , A61K39/395 , A61K39/3955 , A61K39/39566 , A61K2039/505 , C07K16/00 , C07K16/22 , C07K16/2863 , C07K16/2875 , C07K16/2887 , C07K16/2893 , C07K16/2896 , C07K16/32 , C07K16/4291 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/51 , C07K2317/52 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/56 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , C12P21/005 , C40B30/02 , G06F19/12 , G06F19/16 , G06F19/22
摘要: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
摘要翻译: 本发明涉及优化的Fc变体,其产生方法,以及包含优化的Fc变体的抗体和Fc融合体。
-
公开(公告)号:US20130156758A1
公开(公告)日:2013-06-20
申请号:US13773473
申请日:2013-02-21
申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
IPC分类号: A61K39/395
CPC分类号: C07K16/283 , A61K39/395 , A61K39/3955 , A61K39/39566 , A61K2039/505 , C07K16/00 , C07K16/22 , C07K16/2863 , C07K16/2875 , C07K16/2887 , C07K16/2893 , C07K16/2896 , C07K16/32 , C07K16/4291 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/51 , C07K2317/52 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/56 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , C12P21/005 , C40B30/02 , G06F19/12 , G06F19/16 , G06F19/22
摘要: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
-
公开(公告)号:US20130243762A1
公开(公告)日:2013-09-19
申请号:US13898386
申请日:2013-05-20
申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
CPC分类号: C07K16/283 , A61K39/395 , A61K39/3955 , A61K39/39566 , A61K2039/505 , C07K16/00 , C07K16/22 , C07K16/2863 , C07K16/2875 , C07K16/2887 , C07K16/2893 , C07K16/2896 , C07K16/32 , C07K16/4291 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/51 , C07K2317/52 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/56 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , C12P21/005 , C40B30/02 , G06F19/12 , G06F19/16 , G06F19/22
摘要: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
-
公开(公告)号:US20140370021A1
公开(公告)日:2014-12-18
申请号:US13918782
申请日:2013-06-14
申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
IPC分类号: C07K16/32
CPC分类号: C07K16/2893 , C07K16/2887 , C07K2317/41 , C07K2317/52 , C07K2317/732
摘要: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
摘要翻译: 本发明涉及优化的Fc变体,其产生方法,以及包含优化的Fc变体的抗体和Fc融合体。
-
公开(公告)号:US08734791B2
公开(公告)日:2014-05-27
申请号:US13406347
申请日:2012-02-27
申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
IPC分类号: A61K39/395 , A61K39/40 , C07K16/00
CPC分类号: C07K16/00 , A61K2039/505 , C07K16/22 , C07K16/283 , C07K16/2863 , C07K16/2887 , C07K16/2893 , C07K16/2896 , C07K16/30 , C07K16/3015 , C07K16/32 , C07K2317/34 , C07K2317/52 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/734 , C07K2317/77 , C07K2317/92
摘要: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
摘要翻译: 本发明涉及优化的Fc变体,其产生方法,以及包含优化的Fc变体的抗体和Fc融合体。
-
公开(公告)号:US08124731B2
公开(公告)日:2012-02-28
申请号:US11927444
申请日:2007-10-29
申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
CPC分类号: C07K16/00 , A61K2039/505 , C07K16/22 , C07K16/283 , C07K16/2863 , C07K16/2887 , C07K16/2893 , C07K16/2896 , C07K16/30 , C07K16/3015 , C07K16/32 , C07K2317/34 , C07K2317/52 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/734 , C07K2317/77 , C07K2317/92
摘要: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
摘要翻译: 本发明涉及优化的Fc变体,其产生方法,以及包含优化的Fc变体的抗体和Fc融合体。
-
公开(公告)号:US08383109B2
公开(公告)日:2013-02-26
申请号:US13346604
申请日:2012-01-09
申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
IPC分类号: A61K39/40 , A61K39/395 , C07K16/00
CPC分类号: C07K16/283 , A61K39/395 , A61K39/3955 , A61K39/39566 , A61K2039/505 , C07K16/00 , C07K16/22 , C07K16/2863 , C07K16/2875 , C07K16/2887 , C07K16/2893 , C07K16/2896 , C07K16/32 , C07K16/4291 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/51 , C07K2317/52 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/56 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , C12P21/005 , C40B30/02 , G06F19/12 , G06F19/16 , G06F19/22
摘要: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
-
公开(公告)号:US08093359B2
公开(公告)日:2012-01-10
申请号:US11981822
申请日:2007-10-31
申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
CPC分类号: C07K16/283 , A61K39/395 , A61K39/3955 , A61K39/39566 , A61K2039/505 , C07K16/00 , C07K16/22 , C07K16/2863 , C07K16/2875 , C07K16/2887 , C07K16/2893 , C07K16/2896 , C07K16/32 , C07K16/4291 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/51 , C07K2317/52 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/56 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , C12P21/005 , C40B30/02 , G06F19/12 , G06F19/16 , G06F19/22
摘要: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
-
公开(公告)号:US20140377256A1
公开(公告)日:2014-12-25
申请号:US14286825
申请日:2014-05-23
申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
IPC分类号: C07K16/00
CPC分类号: C07K16/00 , C07K16/2863 , C07K16/2887 , C07K16/2893 , C07K16/32 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/734 , C07K2317/92
摘要: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
摘要翻译: 本发明涉及优化的Fc变体,其产生方法,以及包含优化的Fc变体的抗体和Fc融合体。
-
公开(公告)号:US08039592B2
公开(公告)日:2011-10-18
申请号:US11981823
申请日:2007-10-31
申请人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John R. Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
IPC分类号: C07K17/00 , C07K16/00 , C12P21/08 , A61K39/395
CPC分类号: C07K16/283 , A61K39/395 , A61K39/3955 , A61K39/39566 , A61K2039/505 , C07K16/00 , C07K16/22 , C07K16/2863 , C07K16/2875 , C07K16/2887 , C07K16/2893 , C07K16/2896 , C07K16/32 , C07K16/4291 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/51 , C07K2317/52 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/56 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30 , C12P21/005 , C40B30/02 , G06F19/12 , G06F19/16 , G06F19/22
摘要: The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
摘要翻译: 本发明涉及优化的Fc变体,其产生方法,以及包含优化的Fc变体的抗体和Fc融合体。
-
-
-
-
-
-
-
-
-