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公开(公告)号：US08221315B2
公开(公告)日：2012-07-17
申请号：US11115064
申请日：2005-04-26
摘要： The present invention discloses devices and methods for performing intravascular procedures with out cardiac bypass. The devices include various embodiments of temporary filter devices, temporary valves, and prosthetic valves.The temporary filter devices have one or more cannulae which provide access for surgical tools for effecting repair of the cardiac valves. A cannula may have filters of various configurations encircling the distal region of the cannula, which prevent embolitic material from entering the coronary arteries and aorta.The temporary valve devices may also have one or more cannulae which guide the insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve is a disc of flexible, porous, material that acts to filter blood passing therethrough. A set of valve leaflets extend peripherally from the disc. These leaflets can alternately collapse to prevent blood flow through the valve and extend to permit flow.The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. In one embodiment, the prosthetic valves have at least one substantially rigid strut, at least two expandable fixation rings located about the circumference of the base of the apex of the valve, and one or more commissures and leaflets. The prosthetic valves are introduced into the vascular system a compressed state, advanced to the site of implantation, expanded and secured to the vessel wall.
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公开(公告)号：US20130073036A1
公开(公告)日：2013-03-21
申请号：US13617989
申请日：2012-09-14
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： A method of treating a diseased cardiac valve can include implanting a valve prosthesis by compressing the valve prosthesis to a compressed state for delivery and expanding the valve prosthesis to an expanded state for deployment. The valve prosthesis can include a valve fixation device having a plurality of struts, a first circumferential row of cells coupled to the struts, and a second circumferential row of cells coupled to the struts. The struts are substantially rigid such that the struts do not change dimensions between the compressed state and the expanded state. The valve prosthesis can also include a plurality of leaflets and a plurality of commissures. The valve is coupled to the valve fixation device such that the commissures are radially aligned with respective struts of the plurality of struts.
摘要翻译： 治疗患病心脏瓣膜的方法可以包括通过将瓣膜假体压缩到压缩状态来植入瓣膜假体，用于输送和将瓣膜假体膨胀到展开状态以进行展开。 瓣膜假体可以包括具有多个支柱的瓣膜固定装置，联接到支柱的第一圆周排的细胞以及耦合到支柱的第二圆周排细胞。 支柱基本上是刚性的，使得支柱不会在压缩状态和膨胀状态之间改变尺寸。 瓣膜假体还可以包括多个小叶和多个连合。 阀联接到阀固定装置，使得连合件与多个支柱的相应支柱径向对准。
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公开(公告)号：US07470284B2
公开(公告)日：2008-12-30
申请号：US10787057
申请日：2004-02-25
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： The present invention discloses devices and methods for performing intravascular procedures with out cardiac bypass. The devices include various embodiments of temporary filter devices, temporary valves, and prosthetic valves. The temporary filter devices have one or more cannulae which provide access for surgical tools for effecting repair of the cardiac valves. A cannula may have filters of various configurations encircling the distal region of the cannula, which prevent embolitic material from entering the coronary arteries and aorta.The temporary valve devices may also have one or more cannulae which guide the insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve is a disc of flexible, porous, material that acts to filter blood passing therethrough. A set of valve leaflets extend peripherally from the disc. [These leaflets can alternately collapse to prevent blood flow through the valve and extend to permit flow.The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. In one embodiment, the prosthetic valves have at least one substantially rigid strut, at least two expandable fixation rings located about the circumference of the base of the apex of the valve, and one or more commissures and leaflets. The prosthetic valves are introduced into the vascular system a compressed state, advanced to the site of implantation, expanded and secured to the vessel wall.]
摘要翻译： 本发明公开了用心脏旁路进行血管内手术的装置和方法。 这些装置包括临时过滤装置，临时阀和假肢阀的各种实施例。 临时过滤器装置具有一个或多个套管，其提供用于外科手术工具的进入以实现心脏瓣膜的修复。 套管可以具有围绕套管的远侧区域的各种构造的过滤器，其防止栓塞材料进入冠状动脉和主动脉。 临时阀装置还可以具有一个或多个引导阀插入主动脉的套管。 瓣膜装置在主动脉中扩张以占据血管的整个流动路径。 在一个实施例中，临时阀是柔性多孔材料的盘，其用于过滤血液中的血液。 一组瓣叶从圆盘外围延伸。
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公开(公告)号：US09101470B2
公开(公告)日：2015-08-11
申请号：US11115064
申请日：2005-04-26
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： The present invention discloses devices and methods for performing intravascular procedures without cardiac bypass. The devices include various embodiments of temporary filter devices, temporary valves, and prosthetic valves.The temporary filter devices have one or more cannulae which provide access for surgical tools for effecting repair of the cardiac valves. A cannula may have filters of various configurations encircling the distal region of the cannula, which prevent embolitic material from entering the coronary arteries and aorta.The temporary valve devices may also have one or more cannulae which guide the insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve is a disc of flexible, porous, material that acts to filter blood passing therethrough. A set of valve leaflets extend peripherally from the disc. These leaflets can alternately collapse to prevent blood flow through the valve and extend to permit flow.The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. In one embodiment, the prosthetic valves have at least one substantially rigid strut, at least two expandable fixation rings located about the circumference of the base of the apex of the valve, and one or more commissures and leaflets. The prosthetic valves are introduced into the vascular system a compressed state, advanced to the site of implantation, expanded and secured to the vessel wall.
摘要翻译： 本发明公开了一种在没有心脏旁路的情况下执行血管内手术的装置和方法。 这些装置包括临时过滤装置，临时阀和假肢阀的各种实施例。 临时过滤器装置具有一个或多个套管，其提供用于外科手术工具的进入以实现心脏瓣膜的修复。 套管可以具有围绕套管的远侧区域的各种构造的过滤器，其防止栓塞材料进入冠状动脉和主动脉。 临时阀装置还可以具有一个或多个引导阀插入主动脉的套管。 瓣膜装置在主动脉中扩张以占据血管的整个流动路径。 在一个实施例中，临时阀是柔性多孔材料的盘，其用于过滤血液中的血液。 一组瓣叶从圆盘外围延伸。 这些传单可以交替塌缩，以防止血液流过阀门并延伸以允许流动。 假体瓣膜包括固定假体瓣膜至血管壁的瓣膜固定装置。 在一个实施例中，人造瓣膜具有至少一个基本上刚性的支柱，围绕阀的顶点的基部的圆周定位的至少两个可扩张的固定环，以及一个或多个连合和传单。 人造瓣膜被引入血管系统中的压缩状态，前进到植入部位，扩张并固定到血管壁。
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公开(公告)号：US08591574B2
公开(公告)日：2013-11-26
申请号：US13220179
申请日：2011-08-29
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： A method of performing an endovascular procedure within a patient can include inserting a filter into the patient's vascular system to restrict the passage of emboli through the filter while allowing blood to flow through the filter. The method can also include inserting a prosthetic valve into the patient's vascular system in a compressed state, and advancing the prosthetic valve to a site of implantation upstream of the filter. Additionally, the method includes implanting the prosthetic valve at the site of implantation by expanding at least a portion of the prosthetic value, and removing the filter from the patient's vascular system.
摘要翻译： 在患者体内执行血管内手术的方法可以包括将过滤器插入患者的血管系统中以限制栓塞通过过滤器，同时允许血液流过过滤器。 该方法还可以包括将假体瓣膜以压缩状态插入患者的血管系统中，并将人工瓣膜推进到过滤器上游的植入部位。 另外，该方法包括通过扩展假体值的至少一部分并从患者的血管系统移除过滤器来将植入瓣膜植入植入位置。
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公开(公告)号：US06896690B1
公开(公告)日：2005-05-24
申请号：US09700167
申请日：2000-01-27
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： The present invention discloses devices and methods for performing intravascular procedures with out cardiac bypass. The devices include various embodiments of temporary filter devices, temporary valves, and prosthetic valves.The temporary filter devices have one or more cannulae which provide access for surgical tools for effecting repair of the cardiac valves. A cannula may have filters of various configurations encircling the distal region of the cannula, which prevent embolitic material from entering the coronary arteries and aorta.The temporary valve devices may also have one or more cannulae which guide the insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve is a disc of flexible, porous, material that acts to filter blood passing therethrough. A set of valve leaflets extend peripherally from the disc. These leaflets can alternately collapse to prevent blood flow through the valve and extend to permit flow.The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. In one embodiment, the prosthetic valves have at least one substantially rigid strut, at least two expandable fixation rings located about the circumference of the base of the apex of the valve, and one or more commissures and leaflets. The prosthetic valves are introduced into the vascular system a compressed state, advanced to the site of implantation, expanded and secured to the vessel wall.
摘要翻译： 本发明公开了用心脏旁路进行血管内手术的装置和方法。 这些装置包括临时过滤装置，临时阀和假肢阀的各种实施例。 临时过滤器装置具有一个或多个套管，其提供用于外科手术工具的进入以实现心脏瓣膜的修复。 套管可以具有围绕套管的远侧区域的各种构造的过滤器，其防止栓塞材料进入冠状动脉和主动脉。 临时阀装置还可以具有一个或多个引导阀插入主动脉的套管。 瓣膜装置在主动脉中扩张以占据血管的整个流动路径。 在一个实施例中，临时阀是柔性多孔材料的盘，其用于过滤血液中的血液。 一组瓣叶从圆盘外围延伸。 这些传单可以交替塌缩，以防止血液流过阀门并延伸以允许流动。 假体瓣膜包括固定假体瓣膜至血管壁的瓣膜固定装置。 在一个实施例中，人造瓣膜具有至少一个基本上刚性的支柱，围绕阀的顶点的基部的圆周定位的至少两个可扩张的固定环，以及一个或多个连合和传单。 人造瓣膜被引入血管系统中的压缩状态，前进到植入部位，扩张并固定到血管壁。
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公开(公告)号：US08740974B2
公开(公告)日：2014-06-03
申请号：US13617989
申请日：2012-09-14
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： A method of treating a diseased cardiac valve can include implanting a valve prosthesis by compressing the valve prosthesis to a compressed state for delivery and expanding the valve prosthesis to an expanded state for deployment. The valve prosthesis can include a valve fixation device having a plurality of struts, a first circumferential row of cells coupled to the struts, and a second circumferential row of cells coupled to the struts. The struts are substantially rigid such that the struts do not change dimensions between the compressed state and the expanded state. The valve prosthesis can also include a plurality of leaflets and a plurality of commissures. The valve is coupled to the valve fixation device such that the commissures are radially aligned with respective struts of the plurality of struts.
摘要翻译： 治疗患病心脏瓣膜的方法可以包括通过将瓣膜假体压缩到压缩状态来植入瓣膜假体，用于输送和将瓣膜假体膨胀到展开状态以进行展开。 瓣膜假体可以包括具有多个支柱的瓣膜固定装置，耦合到支柱的第一圆周排的细胞以及耦合到支柱的第二圆周排细胞。 支柱基本上是刚性的，使得支柱不会在压缩状态和膨胀状态之间改变尺寸。 瓣膜假体还可以包括多个小叶和多个连合。 阀联接到阀固定装置，使得连合件与多个支柱的相应支柱径向对准。
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公开(公告)号：US20110313446A1
公开(公告)日：2011-12-22
申请号：US13220179
申请日：2011-08-29
IPC分类号： A61F2/01
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2/2427 , A61F2220/0016 , A61F2250/0059
摘要： A method of performing an endovascular procedure within a patient can include inserting a filter into the patient's vascular system to restrict the passage of emboli through the filter while allowing blood to flow through the filter. The method can also include inserting a prosthetic valve into the patient's vascular system in a compressed state, and advancing the prosthetic valve to a site of implantation upstream of the filter. Additionally, the method includes implanting the prosthetic valve at the site of implantation by expanding at least a portion of the prosthetic valve, and removing the filter from the patient's vascular system.
摘要翻译： 在患者体内执行血管内手术的方法可以包括将过滤器插入患者的血管系统中以限制栓塞通过过滤器，同时允许血液流过过滤器。 该方法还可以包括将假体瓣膜以压缩状态插入患者的血管系统中，并将人工瓣膜推进到过滤器上游的植入部位。 另外，该方法包括通过使至少一部分人工瓣膜膨胀并从患者血管系统中移除过滤器将植入假体瓣膜植入植入位置。
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公开(公告)号：US20060253129A1
公开(公告)日：2006-11-09
申请号：US11400714
申请日：2006-04-07
申请人： John Liddicoat , William Cohn
发明人： John Liddicoat , William Cohn
IPC分类号： A61B17/10
CPC分类号： A61B17/12013 , A61B17/00234 , A61B2017/00243
摘要： A novel catheter-based system that ligates the left atrial appendage (LAA) on the outside of the heart, preferably using a combination of catheters and/or instruments, e.g., a guide catheter inserted into the interior of the left atrial appendage that may assist in locating the left atrial appendage and/or assist in the optimal placement of a ligature or constricting element on the outside of the appendage, and a ligating catheter and/or instrument outside the heart in the pericardial space to set the ligature or constricting element at the neck of the left atrial appendage.
摘要翻译： 一种新颖的基于导管的系统，其将心脏外侧的左心耳（LAA）结合，优选地使用导管和/或器械的组合，例如插入左心耳内部的引导导管，其可以协助 在确定左心耳和/或协助在附件外侧的结扎或收缩元件的最佳放置以及在心包空间内的心脏外的结扎导管和/或器械以将结扎或收缩元件设置在 左心耳的颈部。
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10.发明申请Tissue annuloplasty band and apparatus and method for fashioning, sizing and implanting the same 有权组织瓣环成形术带及其形状，尺寸和植入方法公开(公告)号：US20060074486A1
公开(公告)日：2006-04-06
申请号：US11221393
申请日：2005-09-07
申请人： John Liddicoat , Brian Coppom , Richard Streeter
发明人： John Liddicoat , Brian Coppom , Richard Streeter
IPC分类号： A61F2/24 , A61B17/3205
CPC分类号： A61F2/2448 , A61F2/2445 , A61F2/2466 , A61F2/2496 , A61F2250/001
摘要： This invention relates to a system used to fashion, size, and implant a tissue annuloplasty band. This system comprises (1) a device to cut tissue; (2) a device to fashion (i.e., roll, fold, bunch, etc.) the tissue into a band (i.e., the tissue annuloplasty band); and (3) a sizer that comprises an mounting ring which allows for determining and maintaining the proper size and shape of the tissue annuloplasty band while it is attached to the annulus of a heart valve. These components can be used alone, together as a system, or in any combination to fashion, size, and/or implant the tissue annuloplasty band.
摘要翻译： 本发明涉及一种用于对组织瓣环成形术带进行时间，尺寸和植入的系统。 该系统包括（1）切割组织的装置; （2）将组织（即，组织瓣环成形术带）方向（即，卷起，折叠，束等）的装置; 以及（3）包括安装环的定径机，所述安装环允许当其连接到心脏瓣膜的环形空间时，确定和维持组织瓣环成形术带的适当尺寸和形状。 这些组分可以单独使用，一起用作系统，或以任何组合方式使用，尺寸和/或植入组织瓣环成形术带。
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