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公开(公告)号：US07462639B2
公开(公告)日：2008-12-09
申请号：US11384052
申请日：2006-03-17
申请人： Guy Georges , Bernhard Goller , Klaus-Peter Kuenkele , Aude Lemarchand , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth
发明人： Guy Georges , Bernhard Goller , Klaus-Peter Kuenkele , Aude Lemarchand , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth
IPC分类号： A61K31/4155 , C07D487/04
CPC分类号： C07D487/04
摘要： The present invention relates to the compounds of formula I: their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of such compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明涉及式I化合物：其药学上可接受的盐或酯，对映体形式，非对映异构体和外消旋体，上述化合物的制备，含有它们的药物组合物及其制备，以及这些化合物的用途 控制或预防癌症等疾病。
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公开(公告)号：US20060235065A1
公开(公告)日：2006-10-19
申请号：US11384052
申请日：2006-03-17
申请人： Guy Georges , Bernhard Goller , Klaus-Peter Kuenkele , Aude Lemarchand , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth
发明人： Guy Georges , Bernhard Goller , Klaus-Peter Kuenkele , Aude Lemarchand , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth
IPC分类号： A61K31/4188 , C07D487/02
CPC分类号： C07D487/04
摘要： The present invention relates to the compounds of formula I: their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of such compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明涉及式I化合物：其药学上可接受的盐或酯，对映体形式，非对映异构体和外消旋体，上述化合物的制备，含有它们的药物组合物及其制备，以及这些化合物的用途 控制或预防癌症等疾病。
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公开(公告)号：US20060142247A1
公开(公告)日：2006-06-29
申请号：US11301993
申请日：2005-12-13
申请人： Guy Georges , Bernhard Goller , Klaus-Peter Kuenkele , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth , Christine Schuell
发明人： Guy Georges , Bernhard Goller , Klaus-Peter Kuenkele , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth , Christine Schuell
IPC分类号： C07F7/02 , A61K31/695 , A61K31/675 , C07D471/02
CPC分类号： C07D487/04 , C07D471/04
摘要： The present invention relates to the compounds of formula I their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing such compounds and their manufacture, as well as the use of such compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明涉及式I化合物其药学上可接受的盐或酯，对映体形式，非对映异构体和外消旋物，上述化合物的制备，含有这些化合物的药物组合物及其制备方法以及这些化合物的用途 控制或预防癌症等疾病。
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公开(公告)号：US20060235013A1
公开(公告)日：2006-10-19
申请号：US11384058
申请日：2006-03-17
申请人： Guy Georges , Bernhard Goller , Hans-Willi Krell , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth
发明人： Guy Georges , Bernhard Goller , Hans-Willi Krell , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth
IPC分类号： A61K31/5377 , A61K31/4745 , A61K31/4188 , C07D487/04
CPC分类号： C07D487/04 , C07D519/00
摘要： The present invention relates to the compounds of formula I: their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of such compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明涉及式I化合物：其药学上可接受的盐或酯，对映体形式，非对映异构体和外消旋体，上述化合物的制备，含有它们的药物组合物及其制备，以及这些化合物的用途 控制或预防癌症等疾病。
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5.发明申请Tricyclic Lactam Derivatives, Their Manufacture and Use as Pharmaceutical Agents 审中-公开三环内酰胺衍生物，其制造和用作药剂公开(公告)号：US20090143375A1
公开(公告)日：2009-06-04
申请号：US12084531
申请日：2006-12-13
申请人： Guy Georges , Bernhard Goller , Hans-Willi Krell , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth , Christine Schuell , Mark Stahl
发明人： Guy Georges , Bernhard Goller , Hans-Willi Krell , Anja Limberg , Ulrike Reiff , Petra Rueger , Matthias Rueth , Christine Schuell , Mark Stahl
IPC分类号： A61K31/4188 , C07D487/04 , A61P29/00 , A61P9/00 , A61P35/00 , A61P25/00 , A61K31/5377
CPC分类号： C07D487/04
摘要： Objects of the present invention are the compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明的目的是式I化合物，其药学上可接受的盐，对映体形式，非对映异构体和外消旋物，上述化合物的制备，含有它们的药物及其制备，以及上述化合物 控制或预防癌症等疾病。
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公开(公告)号：US07285569B2
公开(公告)日：2007-10-23
申请号：US11233408
申请日：2005-09-23
申请人： Georges Guy , Bernhard Goller , Hans-Willi Krell , Klaus-Peter Kuenkele , Anja Limberg , Petra Rueger , Matthias Rueth
发明人： Georges Guy , Bernhard Goller , Hans-Willi Krell , Klaus-Peter Kuenkele , Anja Limberg , Petra Rueger , Matthias Rueth
IPC分类号： A61K31/4184 , A61K31/4155 , C07D487/02 , C07D403/04
CPC分类号： A61K31/4184 , C07D487/04 , C07D487/10
摘要： The present invention relates to compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明涉及式I化合物的药学上可接受的盐，对映体形式，非对映异构体和外消旋体，上述化合物的制备，含有它们的药物及其制备，以及上述化合物在 控制或预防癌症等疾病。
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公开(公告)号：US20060069145A1
公开(公告)日：2006-03-30
申请号：US11233408
申请日：2005-09-23
申请人： Georges Guy , Bernhard Goller , Hans-Willi Krell , Klaus-Peter Kuenkele , Anja Limberg , Petra Rueger , Matthias Rueth
发明人： Georges Guy , Bernhard Goller , Hans-Willi Krell , Klaus-Peter Kuenkele , Anja Limberg , Petra Rueger , Matthias Rueth
IPC分类号： A61K31/4184 , C07D487/02
CPC分类号： A61K31/4184 , C07D487/04 , C07D487/10
摘要： The present invention relates to compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明涉及式I化合物
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8.发明申请SUBSTITUTED INDAZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS 审中-公开取代的吲哚衍生物，其制造和用作药物代理公开(公告)号：US20090291968A1
公开(公告)日：2009-11-26
申请号：US12293428
申请日：2007-03-21
申请人： Guy Georges , Bernhard Goller , Anja Limberg , Petra Rueger , Matthias Rueth , Christine Schuell , Mark Stahl
发明人： Guy Georges , Bernhard Goller , Anja Limberg , Petra Rueger , Matthias Rueth , Christine Schuell , Mark Stahl
IPC分类号： A61K31/4188 , C07D487/04 , A61K31/4196 , A61K31/4439 , A61K31/506
CPC分类号： C07D487/04
摘要： Objects of the present invention are the compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明的目的是式I化合物，其药学上可接受的盐，对映体形式，非对映异构体和外消旋物，上述化合物的制备，含有它们的药物及其制备，以及上述化合物 控制或预防癌症等疾病。
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9.发明申请PHTHALAZINONE PYRAZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS 审中-公开苯并噻唑酮衍生物及其制备方法及用作药物代理公开(公告)号：US20090221599A1
公开(公告)日：2009-09-03
申请号：US12279894
申请日：2007-03-16
申请人： Edward Boyd , Frederick Brookfield , Steve Courtney , Guy Georges , Bernhard Goller , Anja Limberg , Michael Prime , Petra Rueger , Matthias Rueth
发明人： Edward Boyd , Frederick Brookfield , Steve Courtney , Guy Georges , Bernhard Goller , Anja Limberg , Michael Prime , Petra Rueger , Matthias Rueth
IPC分类号： A61K31/501 , C07D403/12
CPC分类号： C07D403/12 , C07D401/14
摘要： Objects of the present invention are the compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
摘要翻译： 本发明的目的是式I化合物，其药学上可接受的盐，对映体形式，非对映异构体和外消旋物，上述化合物的制备，含有它们的药物及其制备，以及上述化合物 控制或预防癌症等疾病。
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公开(公告)号：US20060089359A1
公开(公告)日：2006-04-27
申请号：US11233311
申请日：2005-09-23
申请人： Edward Boyd , Frederick Brookfield , Guy Georges , Bernhard Goller , Sabine Huensch , Petra Rueger , Matthias Rueth , Stefan Scheiblich , Christine Schuell , Wolfgang von der Saal , Justin Warne , Stefan Weigand
发明人： Edward Boyd , Frederick Brookfield , Guy Georges , Bernhard Goller , Sabine Huensch , Petra Rueger , Matthias Rueth , Stefan Scheiblich , Christine Schuell , Wolfgang von der Saal , Justin Warne , Stefan Weigand
IPC分类号： A61K31/502 , C07D403/02
CPC分类号： C07D403/12
摘要： Compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates are disclosed. Also disclosed are methods for the preparation of the above-mentioned compounds, pharmaceutical compositions containing them, as well as the use of the above-mentioned compounds in the treatment, control or prevention of illnesses such as cancer.
摘要翻译： 公开了式I化合物的药学上可接受的盐，对映体形式，非对映异构体和外消旋体。 还公开了制备上述化合物的方法，含有它们的药物组合物，以及上述化合物在治疗，控制或预防诸如癌症等疾病中的用途。
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