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    Dual chamber pacemaker with safe airial pacing
    1.
    发明授权
    Dual chamber pacemaker with safe airial pacing 失效
    双室心脏起搏器，安全气道起搏

    公开(公告)号：US5273035A

    公开(公告)日：1993-12-28

    申请号：US829811

    申请日：1992-02-03

    申请人： H. Toby Markowitz ,  John C. Stroebel ,  Robert A. Betzold

    发明人： H. Toby Markowitz ,  John C. Stroebel ,  Robert A. Betzold

    IPC分类号： A61N1/362

    CPC分类号： A61N1/3622

    摘要： A dual chamber pacemaker is provided, preferably either DDDR or DDIR, having logic hardware and/or software for normally carrying out the DDIR or DDDR mode of operation, and further having means for carrying out a safe atrial pace method of operation in circumstances where normal atrial pacing could otherwise be competitive or result in loss of atrial capture. The pacemaker has means for detecting an atrial sense during PVARP, timing out a delay from the time of the early atrial sense, delivering a safe atrial pulse at the end of the delay, and controlling generation of a ventricular pace pulse in synchronous relation to the safe atrial pulse and with at least a minimum AV interval.

    摘要翻译： 提供双室起搏器，优选DDDR或DDIR，具有用于正常执行DDIR或DDDR操作模式的逻辑硬件和/或软件，并且还具有用于在正常情况下执行安全心房步速的操作方法的装置 心房起搏可能会有竞争力或导致心房骤停。 起搏器具有在PVARP期间检测心房感觉的手段，从早期心房感觉时刻延迟，在延迟结束时传送安全的心房脉搏，并且控制与心室起搏脉冲的产生同步关系 安全的心房脉搏和至少最小的AV间隔。

    Regularization of ventricular rate during atrial tachyarrhythmia
    2.
    发明授权
    Regularization of ventricular rate during atrial tachyarrhythmia 有权
    房性心律失常期心室率正常化

    公开(公告)号：US06434424B1

    公开(公告)日：2002-08-13

    申请号：US09470120

    申请日：1999-12-22

    申请人： David A. Igel ,  H. Toby Markowitz ,  Robert A. Betzold ,  Karen J. Kleckner ,  Jeremy A. Schroetter

    发明人： David A. Igel ,  H. Toby Markowitz ,  Robert A. Betzold ,  Karen J. Kleckner ,  Jeremy A. Schroetter

    IPC分类号： A61N1362

    CPC分类号： A61N1/3622

    摘要： A pacing system provided with a mode switching feature and ventricular rate regularization (VRR) function adapted to stabilize or regularize ventricular heart rate during chronic or paroxysmal atrial tachyarrhythmia. In a preferred embodiment, the pacing system nominally operates in an atrial synchronized pacing mode such as DDD or DDDR pacing mode. In response to detection of atrial rhythm characteristics consistent with an atrial tachyarrhythmia, e.g., atrial fibrillation, a mode switch into a non-atrial synchronized, ventricular rate regularization pacing mode, e.g. DDIR or VDIR pacing mode, is made. If the VRR function is programmed on, the ventricular pacing rate based upon a rate responsive sensor derived ventricular pacing rate modulated on a beat by beat basis by preceding intrinsic or paced ventricular events, the stability of the intrinsic ventricular heart rate, and any atrial pace events to regularize the ventricular pacing rate. The pacing system may also be permanently programmed to the DDIR pacing mode with the VRR feature functioning continuously. The pacing system may also be permanently programmed to the VVIR pacing mode with VRR function activated, but without consideration of atrial pace events.

    摘要翻译： 具有模式切换特征和心室率正常化（VRR）功能的起搏系统适于在慢性或阵发性房性快速性心律失常期间稳定或规范心室心率。 在优选实施例中，起搏系统名义地以心房同步起搏模式操作，例如DDD或DDDR起搏模式。 响应于检测与房性快速性心律失常（例如心房颤动）一致的心房节律特征，模式切换到非心房同步的心室速率正则化起搏模式，例如心房颤动。 DDIR或VDIR起搏模式。 如果VRR功能被编程，则基于速率响应传感器导出的心室起搏速率的心室起搏速率通过前进的内在或节奏心室事件，内部心室心率的稳定性和任何心房起搏 事件来规范心室起搏率。 起搏系统也可以永久编程到DDIR起搏模式，VRR功能连续工作。 起搏系统也可以被永久编程到VVIR起搏模式，VRR功能被激活，但不考虑心房速度事件。

    System and method for ventricular pacing with progressive conduction check interval
    3.
    发明授权
    System and method for ventricular pacing with progressive conduction check interval 有权
    具有渐进传导检查间隔的心室起搏的系统和方法

    公开(公告)号：US07881793B2

    公开(公告)日：2011-02-01

    申请号：US11096436

    申请日：2005-03-31

    申请人： Robert A. Betzold ,  David A. Casavant ,  Paul A. Belk ,  Thomas J. Mullen ,  John C. Stroebel

    发明人： Robert A. Betzold ,  David A. Casavant ,  Paul A. Belk ,  Thomas J. Mullen ,  John C. Stroebel

    IPC分类号： A61N1/368

    CPC分类号： A61N1/368 ,  A61N1/3688

    摘要： A pacing protocol is provided that reduces or minimizes ventricular pacing in favor of intrinsic conduction. When operating in a mode that provides ventricular pacing, a series of conduction checks are performed to determine if intrinsic conduction has returned. These conduction checks occur according to a predetermined pattern that general includes longer intervals between subsequent attempts. A maximum interval is provided such that conduction checks are not repeated sequentially at the same time of day when at this maximum interval.

    摘要翻译： 提供起搏方案，其减少或最小化心室起搏以有利于内在传导。 当以提供心室起搏的模式操作时，执行一系列导通检查以确定是否内部传导已经返回。 这些传导检查根据预定的模式进行，通常在后续尝试之间包括更长的间隔。 提供最大间隔，使得在该最大间隔的同一天的相同时间不顺序重复传导检查。

    System and method for ventricular pacing with AV interval modulation
    5.
    发明授权
    System and method for ventricular pacing with AV interval modulation 有权
    使用AV间期调制的心室起搏的系统和方法

    公开(公告)号：US07738955B2

    公开(公告)日：2010-06-15

    申请号：US11115605

    申请日：2005-04-27

    申请人： Michael O. Sweeney ,  David A. Casavant ,  Robert A. Betzold ,  Paul A. Belk ,  Thomas J. Mullen ,  John C. Stroebel

    发明人： Michael O. Sweeney ,  David A. Casavant ,  Robert A. Betzold ,  Paul A. Belk ,  Thomas J. Mullen ,  John C. Stroebel

    IPC分类号： A61N1/372

    CPC分类号： A61N1/368 ,  A61N1/3682

    摘要： A pacing protocol is provided that reduces or minimizes ventricular pacing in favor of intrinsic conduction. When operating in a mode that provides ventricular pacing, a series of conduction checks are performed to determine if intrinsic conduction has returned. These conduction checks occur according to a predetermined pattern that generally includes longer intervals between subsequent attempts. The AV interval provided for dual chamber based pacing is modulated and generally moves from a larger value to a nominal value as the interval between unsuccessful conduction checks increases.

    摘要翻译： 提供起搏方案，其减少或最小化心室起搏以有利于内在传导。 当以提供心室起搏的模式操作时，执行一系列导通检查以确定是否内部传导已经返回。 这些传导检查根据通常在后续尝试之间具有较长间隔的预定模式进行。 为双室起搏提供的AV间隔被调制，并且通常从较大的值移动到不成功的传导检查之间的间隔增加到标称值。

    Implantable medical device with adaptive operation
    10.
    发明授权
    Implantable medical device with adaptive operation 有权
    具有适应性操作的植入式医疗器械

    公开(公告)号：US09415227B2

    公开(公告)日：2016-08-16

    申请号：US13280918

    申请日：2011-10-25

    申请人： Robert A. Betzold

    发明人： Robert A. Betzold

    IPC分类号： A61N1/00 ,  A61N1/37 ,  A61N1/368

    CPC分类号： A61N1/37 ,  A61N1/368 ,  A61N1/3718

    摘要： An implantable medical device operates with an algorithm that promotes intrinsic conduction and reduces ventricular pacing. The IMD monitors the occurrence of necessary ventricular pacing and takes certain actions based upon whether this occurrence has been relatively high or relatively low. When noise is detected, asynchronous pacing is provided when the occurrence is relatively high and is not provided when relatively low. When atrial threshold testing is performed, the incidence will determine which methodology is utilized.

    摘要翻译： 可植入医疗装置利用促进内在传导并降低心室起搏的算法进行操作。 IMD监测必要的心室起搏的发生，并根据这种情况是否相对较高或相对较低来采取某些行动。 当检测到噪声时，当发生相对较高时提供异步起搏，并且当相对较低时不提供异步起搏。 当进行心房阈值测试时，发病率将决定哪种方法被利用。