公开(公告)号：US3892678A

公开(公告)日：1975-07-01

申请号：US37970573

申请日：1973-07-16

Applicant: HALASZ ISTVAN

Inventor： HALASZ ISTVAN ,  BRUST OTTO-ERNST ,  SEBESTIAN IMRICH

IPC: B01J20/32 ,  B01J31/02

CPC classification number: B01J20/28069 ,  B01J20/103 ,  B01J20/28004 ,  B01J20/28057 ,  B01J20/28078 ,  B01J20/286 ,  B01J20/3204 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/3253 ,  B01J2220/54 ,  B01J2220/58

Abstract: The surfaces of porous silicon dioxide chromatographic adsorption means are altered by chemical reaction of silanol groups with primary or secondary aliphatic or araliphatic amines having at least two carbon atoms and containing no functional groups as substituents that might competitively react with respect to the amino groups. The amines are preferably substituted in the omega-position with at least one noncompetitive functional group. Such terminal functional groups may subsequently be reacted with compounds which further alter the surface to provide optimal surface groups in the stationary phase for given separation and chromatographic problems.

Abstract translation: 多孔二氧化硅色谱吸附装置的表面通过硅烷醇基团与具有至少两个碳原子的伯或仲脂族或芳脂族胺的化学反应而改变，并且不含作为相对于氨基竞争性反应的取代基的官能团。 胺优选在ω-位被至少一个非竞争性官能团取代。 随后可以使这样的末端官能团与进一步改变表面的化合物反应，以在固定相中提供用于给定分离和色谱问题的最佳表面基团。