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公开(公告)号:US11914012B2
公开(公告)日:2024-02-27
申请号:US17346468
申请日:2021-06-14
IPC分类号: A61B5/245 , A61B5/055 , G01R33/26 , G01R33/48 , G01R33/032 , G01R33/421 , A61B5/00 , G01R33/00
CPC分类号: G01R33/4806 , A61B5/0042 , A61B5/055 , A61B5/245 , A61B5/6803 , G01R33/0017 , G01R33/032 , G01R33/26 , G01R33/4215 , A61B2562/0223 , A61B2562/182 , G01R33/0076
摘要: A brain measurement apparatus includes: a magnetoencephalograph including optically pumped magnetometers, magnetic sensors for measuring a static magnetic field at positions of the optically pumped magnetometers, and a nulling coil for canceling the static magnetic field; an MRI apparatus including a permanent magnet, a gradient magnetic field coil, a transmission coil, and a receive coil for detecting a nuclear magnetic resonance signal; and a control device that, when measuring the brain's magnetic field, controls a current to be supplied to the nulling coil based on measured values of the magnetic sensors and operates so as to cancel a static magnetic field at the position of each of the optically pumped magnetometers and, when measuring an MR image, controls the gradient magnetic field by controlling a current to be supplied to the gradient magnetic field coil and generates an MR image based on an output of the receive coil.
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公开(公告)号:US11099245B2
公开(公告)日:2021-08-24
申请号:US16547772
申请日:2019-08-22
发明人: Tetsuo Kobayashi , Norihisa Kato , Motohiro Suyama
IPC分类号: G01R33/26 , G01R33/032 , G01N24/00 , H01S3/091
摘要: A cell for a optically pumped magnetic sensor measures magnetic field by setting alkali metal atoms to a predetermined excitation state by a pump beam and detecting the excitation state by a probe beam. The cell is provided with a glass substrate which seals the alkali metal atoms and an enclosing gas and transmits the pump beam and the probe beam and a coating layer provided on an inner surface of the glass substrate. The coating layer is made of an inorganic material.
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公开(公告)号:US11500043B2
公开(公告)日:2022-11-15
申请号:US17346551
申请日:2021-06-14
IPC分类号: G01R33/26
摘要: A magnetoencephalograph M1 includes: multiple pump-probe type optically pumped magnetometers 1A; a bias magnetic field forming coil 15 for applying a bias magnetic field in the same direction as a direction of pump light of each of the multiple pump-probe type optically pumped magnetometers 1A and in a direction approximately parallel to a scalp; a control device 5 that determines a current for the bias magnetic field forming coil and outputs a control signal corresponding to the determined current; and a coil power supply 6 that outputs a current to the bias magnetic field forming coil in response to the control signal output from the control device.
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公开(公告)号:US11835603B2
公开(公告)日:2023-12-05
申请号:US17829413
申请日:2022-06-01
IPC分类号: G01R33/26
CPC分类号: G01R33/26
摘要: An optically pumped magnetometer includes cells configured to form a first cell region and a second cell region on a measurement target, a pump laser, a probe laser, a first optical system configured to cause pump light to be incident on the first cell region, a second optical system configured to cause the pump light having passed through the first cell region to be incident on the second cell region, a third optical system configured to cause first probe light to be incident on the first cell region, a fourth optical system configured to cause second probe light to be incident on the second cell region, detection portions configured to detect the first probe light having passed through the first cell region and the second probe light having passed through the second cell region, and a deriving portion configured to derive an intensity of a magnetic field.
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公开(公告)号:US11957472B2
公开(公告)日:2024-04-16
申请号:US17346338
申请日:2021-06-14
IPC分类号: A61B5/055 , A61B5/00 , A61B5/245 , G01R33/00 , G01R33/26 , G01R33/34 , G01R33/421 , G01R33/54
CPC分类号: A61B5/245 , A61B5/055 , A61B5/6803 , G01R33/0017 , G01R33/26 , G01R33/34084 , G01R33/4215 , G01R33/543
摘要: A brain measurement apparatus includes: a magnetoencephalograph including optically pumped magnetometers, magnetic sensors for measuring geomagnetic field at positions of the optically pumped magnetometers, magnetic sensors for measuring a fluctuating magnetic field at the positions of the optically pumped magnetometers, nulling coils for cancelling the geomagnetic field, and an active shield coil for cancelling the fluctuating magnetic field; an MRI apparatus including nulling coils for applying a static magnetic field and a gradient magnetic field, a transmission coil, and a receive coil; and a control device that, when measuring a brain's magnetic field, controls currents supplied to the nulling coils and the active shield coil based on measured values of the magnetic sensors and, when measuring an MR image, controls the static magnetic field and the gradient magnetic field by controlling currents supplied to the nulling coils and generates an MR image from an output of the receive coil.
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公开(公告)号:US11874348B2
公开(公告)日:2024-01-16
申请号:US17891467
申请日:2022-08-19
IPC分类号: G01R33/3415 , A61B5/055 , G01R33/385
CPC分类号: G01R33/3415 , A61B5/055 , G01R33/385
摘要: Provided is a brain measurement system including: a geomagnetic correction coil; a geomagnetic gradient correction coil; a transmission coil; a receiving coil; a plurality of resonance adjustment circuits; a plurality of OPM modules provided corresponding to each of the plurality of resonance adjustment circuits for detecting a signal having a resonance frequency output from the resonance adjustment circuit; and a control device for generating an MR image based on the signal detected by the OPM module, wherein, when a direction parallel to a central axis of a head portion of a subject is defined as a Z-axis direction, the resonance frequency related to each of the plurality of resonance adjustment circuits is set according to a magnetic field gradient in the Z-axis direction generated by control of a position of the corresponding receiving coil in the Z-axis direction and a tilted magnetic field.
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公开(公告)号:US11619689B2
公开(公告)日:2023-04-04
申请号:US17346322
申请日:2021-06-14
IPC分类号: G01R33/26
摘要: An optically pumped magnetometer 1 includes: a cell 2; a pump laser 7 that emits pump light; one or more pump light mirrors that cause the pump light guided in a first direction; a probe laser 8 that emits probe light; a splitting unit 12 that splits the probe light into multiple light components; one or more probe light mirrors that cause each of the probe light components guided in a second direction, which is a direction perpendicular to the first direction; a detection unit that detects each of the probe light components perpendicular to the pump light inside the cell 2; and a derivation unit that derives a magnetic field corresponding to a region where each of the probe light components and the pump light are perpendicular to each other based on a detection result of the detection unit.
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