公开(公告)号：US20150119373A1

公开(公告)日：2015-04-30

申请号：US14395668

申请日：2013-04-19

Applicant: HETERO RESEARCH FOUNDATION

Inventor： Bandi Parthasaradhi Reddy ,  Vedula Manohar Sharma ,  Kura Rathnakar Reddy ,  Mamnoor Prem Kumar ,  Kasireddy Bhaskar Reddy ,  Mogili Narsingam ,  Mukkera Venkati ,  Lanka VL Subrahmanyam ,  Ravi Mallikarjun Reddy

IPC: C07J53/00

CPC classification number: C07J53/002 ,  C07J63/008

Abstract: The invention relates to novel betulinic acid derivatives and related compounds, and pharmaceutical compositions useful for therapeutic treatment of viral diseases and particularly HIV mediated diseases.

Abstract translation: 本发明涉及新颖的桦木酸衍生物和相关化合物，以及可用于治疗性治疗病毒性疾病，特别是HIV介导的疾病的药物组合物。

公开(公告)号：US20180148412A1

公开(公告)日：2018-05-31

申请号：US15882317

申请日：2018-01-29

Applicant: HETERO RESEARCH FOUNDATION

Inventor： Bandi Parthasaradhi Reddy ,  Kura Rathnakar Reddy ,  Dsari Muralidhara Reddy ,  Mogili Narsingam ,  Bandi Vamsi Krishna

IPC: C07D213/82 ,  C07D213/79 ,  C07C231/02 ,  C07D213/14

CPC classification number: C07D213/82 ,  C07C231/02 ,  C07D213/14 ,  C07D213/69 ,  C07D213/79 ,  C07D213/80 ,  C07D213/81 ,  C07D309/40 ,  C07D498/12

Abstract: The present invention provides a novel processes for preparation of methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyiridine-2-carboxylate using novel intermediates.

公开(公告)号：US20170334858A1

公开(公告)日：2017-11-23

申请号：US14968088

申请日：2015-12-14

Applicant: HETERO RESEARCH FOUNDATION

Inventor： Bandi Parthasaradhi Reddy ,  Kura Rathnakar Reddy ,  Dasari Muralidhara Reddy ,  Mogili Narsingam ,  Bandi Vamsi Krishna

IPC: C07D213/82 ,  C07C231/02 ,  C07D213/14 ,  C07D213/79

CPC classification number: C07D213/82 ,  C07C231/02 ,  C07D213/14 ,  C07D213/69 ,  C07D213/79 ,  C07D213/80 ,  C07D213/81 ,  C07D309/40 ,  C07D498/12

Abstract: The present invention provides a novel processes for preparation of methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyiridine-2-carboxylate using novel intermediates.

公开(公告)号：US10442769B2

公开(公告)日：2019-10-15

申请号：US15882317

申请日：2018-01-29

Applicant: HETERO RESEARCH FOUNDATION

Inventor： Bandi Parthasaradhi Reddy ,  Kura Rathnakar Reddy ,  Dsari Muralidhara Reddy ,  Mogili Narsingam ,  Bandi Vamsi Krishna

IPC: C07C231/02 ,  C07D213/14 ,  C07D213/69 ,  C07D213/79 ,  C07D213/80 ,  C07D213/81 ,  C07D213/82 ,  C07D309/40 ,  C07D498/12

Abstract: The present invention provides a novel processes for preparation of methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyiridine-2-carboxylate using novel intermediates.

公开(公告)号：US09963430B2

公开(公告)日：2018-05-08

申请号：US14968088

申请日：2015-12-14

Applicant: HETERO RESEARCH FOUNDATION

Inventor： Bandi Parthasaradhi Reddy ,  Kura Rathnakar Reddy ,  Dasari Muralidhara Reddy ,  Mogili Narsingam ,  Bandi Vamsi Krishna

IPC: C07D213/02 ,  C07D213/79 ,  C07D213/82 ,  C07C231/02 ,  C07D213/14

CPC classification number: C07D213/82 ,  C07C231/02 ,  C07D213/14 ,  C07D213/69 ,  C07D213/79 ,  C07D213/80 ,  C07D213/81 ,  C07D309/40 ,  C07D498/12

Abstract: The present invention provides a novel processes for preparation of methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyiridine-2-carboxylate using novel intermediates.