公开(公告)号：US11607394B2

公开(公告)日：2023-03-21

申请号：US16954627

申请日：2018-12-14

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Hiroyuki Araki ,  Yuka Takagi ,  Yoko Fujiwara ,  Hiroaki Kobayashi ,  Takao Kurokawa

IPC: A61P25/16 ,  A61K47/32 ,  A61K31/381 ,  A61K9/70

Abstract: The present invention provides a rotigotine-containing patch comprising: a backing layer; and an adhesive agent layer, wherein the adhesive agent layer contains rotigotine and/or a pharmaceutically acceptable salt thereof,
the adhesive agent layer further contains a styrene-based thermoplastic elastomer, a petroleum-based resin and/or a terpene-based resin, an aliphatic alcohol, and a cross-linked polyvinylpyrrolidone, and
in the adhesive agent layer, a mass ratio of a content of the rotigotine and/or the pharmaceutically acceptable salt thereof in terms of rotigotine free form and a content of the cross-linked polyvinylpyrrolidone (content of the rotigotine and/or the pharmaceutically acceptable salt thereof in terms of rotigotine free form:content of the cross-linked polyvinylpyrrolidone) is 10:3 to 1:3.