公开(公告)号：US20220273603A1

公开(公告)日：2022-09-01

申请号：US17682205

申请日：2022-02-28

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Kana IMAMURA ,  Naoko FUJITA ,  Yasunari MICHINAKA

IPC: A61K31/222 ,  A61K9/00 ,  A61K47/10 ,  A61K47/02

Abstract: A method for treating hyperhidrosis is disclosed. The method comprises administering a liquid topical preparation to a patient in need thereof. The liquid topical preparation comprises water and oxybutynin or a pharmaceutically acceptable salt thereof. The oxybutynin or pharmaceutically acceptable salt thereof is present in a range of, for example, from 10 mass % to 20 mass % based on a total mass of the liquid topical preparation.

公开(公告)号：US20160354322A1

公开(公告)日：2016-12-08

申请号：US15114979

申请日：2015-01-28

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Yasunari MICHINAKA ,  Tomohiro SHINODA ,  Kana IMAMURA

IPC: A61K9/70 ,  A61K47/18 ,  A61K31/551

CPC classification number: A61K9/7053 ,  A61K9/70 ,  A61K9/703 ,  A61K31/551 ,  A61K47/18 ,  A61K47/32 ,  A61K47/34

Abstract: Provided is an emedastine-containing tape preparation comprising a support film, and a pressure-sensitive adhesive layer laminated on the support film, wherein the pressure-sensitive adhesive layer comprises emedastine, a fumarate salt of an organic amine, and a pressure-sensitive adhesive.

Abstract translation: 本发明提供含有依托汀的胶带制剂，其包含支撑膜和层压在支持膜上的压敏粘合剂层，其中压敏粘合剂层包含依达斯汀，有机胺的富马酸盐和压敏粘合剂 。

公开(公告)号：US20190046493A1

公开(公告)日：2019-02-14

申请号：US16079208

申请日：2016-10-26

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Kana IMAMURA ,  Naoko FUJITA ,  Yasunari MICHINAKA

IPC: A61K31/216 ,  A61K47/14 ,  A61K47/12 ,  A61K47/02 ,  A61K9/00 ,  A61P17/00

Abstract: The present invention provides a liquid topical preparation having low “stickiness” even when it contains a high concentration of an anticholinergic drug. The liquid topical preparation comprises water, an anticholinergic drug and dicarboxylic acid ester, and the content of the anticholinergic drug ranges from 10 mass % to 20 mass % based on the total mass of the liquid topical preparation.

公开(公告)号：US20180140704A1

公开(公告)日：2018-05-24

申请号：US15568432

申请日：2016-04-27

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Kana IMAMURA ,  Tomohiro SHINODA ,  Shingo SOMEKAWA ,  Yasunari MICHINAKA

IPC: A61K47/12 ,  A61K9/00 ,  A61P17/00 ,  A61K31/216

Abstract: The present invention provides a topical preparation for treating hyperhidrosis, comprising water, an anticholinergic drug, and one or more salts selected from the group consisting of lactate, tartrate, acetate and phosphate. Such a topical preparation comprises the above certain salt, thereby facilitating the accumulation of the anticholinergic drug in skin appendages.