公开(公告)号：US20160317465A1

公开(公告)日：2016-11-03

申请号：US15103768

申请日：2014-12-10

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Tomohiro SHINODA ,  Yasunari MICHINAKA

IPC: A61K9/70 ,  A61K31/137 ,  A61K31/551 ,  A61K31/27

CPC classification number: A61K9/7084 ,  A61K9/7053 ,  A61K9/7061 ,  A61K31/137 ,  A61K31/27 ,  A61K31/325 ,  A61K31/551 ,  A61K47/32

Abstract: A cover material-equipped patch comprising: a patch; and a cover material, wherein the patch comprises a support layer and a drug reservoir layer which is stacked on one surface of the support layer and which contains a drug and a drug reservoir base agent, the cover material comprises a cover layer and an adhesive layer which is stacked on one surface of the cover layer and which contains an adhesive base agent, the patch and the cover material are arranged in such a manner that the adhesive layer is stacked on another surface of the support layer, and a solubility parameter (SPa) of the drug, a solubility parameter (SPb) of the drug reservoir base agent, and a solubility parameter (SPc) of the adhesive base agent simultaneously satisfy conditions represented by the following formulae (1) to (3): 0≦|SPa−SPb|≦1.5  (1), 2.0≦(SPa−SPc)≦2.8  (2), and 1.0≦(SPb−SPc)≦2.8  (3).

Abstract translation: 一种装有覆盖材料的贴片，包括：贴片; 和覆盖材料，其中所述贴片包括支撑层和药物储存层，所述支撑层和药物储存层层叠在所述支撑层的一个表面上并且包含药物和药物储存剂基剂，所述覆盖材料包括覆盖层和粘合剂层 其叠层在覆盖层的一个表面上并且包含粘合剂基剂，贴片和覆盖材料以使得粘合剂层堆叠在支撑层的另一个表面上的方式布置，并且溶解度参数（SPa ），药物储库基剂的溶解度参数（SPb）和粘合剂基剂的溶解度参数（SPc）同时满足下述式（1）〜（3）所示的条件：0‰×SPa 'SPb‰¤1.5 2.0‰¤SPa'SPc‰2.8和1.0‰SPb'SPc‰2.8

公开(公告)号：US20160354322A1

公开(公告)日：2016-12-08

申请号：US15114979

申请日：2015-01-28

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Yasunari MICHINAKA ,  Tomohiro SHINODA ,  Kana IMAMURA

IPC: A61K9/70 ,  A61K47/18 ,  A61K31/551

CPC classification number: A61K9/7053 ,  A61K9/70 ,  A61K9/703 ,  A61K31/551 ,  A61K47/18 ,  A61K47/32 ,  A61K47/34

Abstract: Provided is an emedastine-containing tape preparation comprising a support film, and a pressure-sensitive adhesive layer laminated on the support film, wherein the pressure-sensitive adhesive layer comprises emedastine, a fumarate salt of an organic amine, and a pressure-sensitive adhesive.

Abstract translation: 本发明提供含有依托汀的胶带制剂，其包含支撑膜和层压在支持膜上的压敏粘合剂层，其中压敏粘合剂层包含依达斯汀，有机胺的富马酸盐和压敏粘合剂 。

公开(公告)号：US20140329063A1

公开(公告)日：2014-11-06

申请号：US14339487

申请日：2014-07-24

Applicant: HISAMITSU PHARMACEUTICAL CO., INC. ,  TOPPAN PRINTING CO., LTD. ,  MARUTO SANGYO CO., LTD.

Inventor： Tomohiro SHINODA ,  Hisaaki ISAJI ,  Yasunori TAKADA ,  Tsuguki NISHIHARA ,  Atsushi MATSUSHIMA ,  Chiaki YOSHIDA ,  Tsuyoshi TAKAMIYA

IPC: C09J7/02

CPC classification number: C09J7/0282 ,  B32B7/12 ,  B32B27/08 ,  B32B27/22 ,  B32B27/306 ,  B32B27/40 ,  B32B2255/10 ,  B32B2255/26 ,  B32B2307/728 ,  B32B2555/02 ,  C08J7/04 ,  C08J7/045 ,  C08J2375/04 ,  C08L75/04 ,  C09J7/25 ,  C09J7/29 ,  C09J2429/001 ,  C09J2475/006 ,  Y10T428/24851 ,  Y10T428/2848 ,  Y10T428/31551

Abstract: A support film for tape which is used for a tape includes a film-shaped support formed of polyurethane, a barrier layer which includes polyvinyl alcohol and a layered inorganic compound and is formed on a surface of the support, and an undercoat layer which is disposed between the support and the barrier layer, and which causes the support and the barrier layer to adhere to each other.

Abstract translation: 用于胶带的胶带用支撑膜包括由聚氨酯形成的膜状支撑体，包含聚乙烯醇和层状无机化合物的阻挡层，并且形成在载体的表面上，并且设置有底涂层 在支撑体和阻挡层之间，并且使得支撑体和阻挡层彼此粘附。

公开(公告)号：US20250161265A1

公开(公告)日：2025-05-22

申请号：US18839471

申请日：2023-02-15

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Kimiko KAWAI ,  Tomohiro SHINODA ,  Takao KUROKAWA

IPC: A61K31/381 ,  A61K47/14 ,  A61K47/20

Abstract: A rotigotine-containing patch including a backing layer and an adhesive agent layer, wherein the adhesive agent layer comprises at least one selected from the group consisting of rotigotine and a pharmaceutically acceptable salt of rotigotine, and the adhesive agent layer further comprises an adhesive base agent, and at least one selected from the group consisting of thioglycolic acid and a pharmaceutically acceptable salt of thioglycolic acid.

公开(公告)号：US20190161647A1

公开(公告)日：2019-05-30

申请号：US16263525

申请日：2019-01-31

Applicant: TOPPAN PRINTING CO., LTD. ,  HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Koji SAKAIRI ,  Atsushi MATSUSHIMA ,  Tomohiro SHINODA ,  Atsushi SONOBE

IPC: C09J7/29 ,  C09J201/02

Abstract: A support film for a tape material, includes a film-shaped support formed of polyurethane; and a barrier layer containing an aromatic isocyanate-based polyurethane and a layered inorganic compound and formed on one surface of the support.

公开(公告)号：US20160374956A1

公开(公告)日：2016-12-29

申请号：US15103449

申请日：2014-12-10

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Tomohiro SHINODA ,  Yasunari MICHINAKA

IPC: A61K9/70 ,  A61K47/32 ,  A61K31/325

CPC classification number: A61K9/7084 ,  A61K9/7053 ,  A61K9/7061 ,  A61K31/137 ,  A61K31/27 ,  A61K31/325 ,  A61K31/551 ,  A61K47/32

Abstract: A multilayer-type patch comprising: a support layer; a drug reservoir layer; and an adhesive layer, wherein the drug reservoir layer comprises at least one drug selected from the group consisting of rivastigmine and pharmaceutically acceptable salts thereof, and a hydroxy group-containing acrylic-based polymer (A), the adhesive layer comprises at least one acrylic-based polymer (B) selected from the group consisting of carboxy group-containing alkyl (meth)acrylate copolymer and acrylic acid homopolymer, and a rubber-based adhesive base agent, a content of the drug in the drug reservoir layer in terms of rivastigmine in free form is 15 to 45% by mass relative to a total mass of the drug reservoir layer, and a total content of the acrylic-based polymer (B) in the adhesive layer is 7 to 18% by mass relative to a total mass of the adhesive layer.

Abstract translation: 一种装有覆盖材料的贴片，包括：贴片; 和覆盖材料，其中所述贴片包括支撑层和药物储存层，所述支撑层和药物储存层层叠在所述支撑层的一个表面上并且包含药物和药物储存剂基剂，所述覆盖材料包括覆盖层和粘合剂层 其叠层在覆盖层的一个表面上并且包含粘合剂基剂，贴片和覆盖材料以使得粘合剂层堆叠在支撑层的另一个表面上的方式布置，并且溶解度参数（SPa ），药物储库基剂的溶解度参数（SPb）和粘合剂基剂的溶解度参数（SPc）同时满足下述式（1）〜（3）所示的条件：0‰×SPa 'SPb‰¤1.5 2.0‰¤SPa'SPc‰2.8和1.0‰SPb'SPc‰2.8

公开(公告)号：US20190160797A1

公开(公告)日：2019-05-30

申请号：US16263846

申请日：2019-01-31

Applicant: TOPPAN PRINTING CO., LTD. ,  HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Koji SAKAIRI ,  Atsushi MATSUSHIMA ,  Tomohiro SHINODA ,  Atsushi SONOBE

IPC: B32B27/28 ,  B32B27/30 ,  B32B27/40 ,  C09J201/00 ,  C08G18/28 ,  C08G18/70 ,  C09D175/04

Abstract: A support film for a tape material is provided that includes a film-shaped support formed of polyurethane, a barrier layer containing an aromatic isocyanate-based polyurethane and a layered inorganic compound and formed on one surface of the support, and an overcoat layer containing a polyvinyl alcohol or an ethylene-vinyl alcohol copolymer and an organometallic chelating agent.

公开(公告)号：US20180140704A1

公开(公告)日：2018-05-24

申请号：US15568432

申请日：2016-04-27

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Kana IMAMURA ,  Tomohiro SHINODA ,  Shingo SOMEKAWA ,  Yasunari MICHINAKA

IPC: A61K47/12 ,  A61K9/00 ,  A61P17/00 ,  A61K31/216

Abstract: The present invention provides a topical preparation for treating hyperhidrosis, comprising water, an anticholinergic drug, and one or more salts selected from the group consisting of lactate, tartrate, acetate and phosphate. Such a topical preparation comprises the above certain salt, thereby facilitating the accumulation of the anticholinergic drug in skin appendages.